{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T11:06:50Z","timestamp":1790248010264,"version":"4.1.0"},"reference-count":56,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background and Clinical Significance: Mesonephric-like adenocarcinoma (MLA) of the ovary is a very rare entity that has only recently been recognized as a distinct subtype in the World Health Organization (WHO) classification. It is an aggressive tumor with a propensity for recurrence. The aim of this case report was to highlight the diagnostic challenges associated with MLA and the importance of immunohistochemical and molecular testing. Case Presentation: We report the case of a 59-year-old woman who presented with a left ovarian tumor. Histopathological examination led to an initial diagnosis of low-grade serous carcinoma, and the patient was treated accordingly. Five years later, the tumor recurred in the bladder wall and was initially interpreted as urothelial carcinoma. One year later, a further recurrence was identified at the vaginal cuff. Integrated review of the original ovarian tumor and recurrent lesions, together with immunohistochemical and molecular findings, supported the diagnosis of ovarian MLA with bladder and vaginal recurrences. Conclusions: Ovarian MLA is extremely rare and can mimic more common ovarian carcinoma subtypes. Awareness of its morphological and immunohistochemical features is essential to avoid misdiagnosis. MLA should be considered in recurrent gynecologic tumors with mesonephric morphology\/immunophenotype even when the recurrence occurs in an unusual site such as the bladder and mimics a primary urinary malignancy.<\/jats:p>","DOI":"10.3390\/diagnostics16193099","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:16:28Z","timestamp":1790244988000},"page":"3099","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Recurrent\u00a0Mesonephric-like Adenocarcinoma of the Ovary with Bladder and Vaginal Recurrences: A Diagnostic Challenge"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8407-4696","authenticated-orcid":false,"given":"Anca","family":"Evsei-Seceleanu","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"},{"name":"Department of Pathology, Saint Mary Clinical Hospital, 011192 Bucharest, Romania"},{"name":"Department of Pathology and Molecular Biology, Pathoteam Diagnostic, 051923 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tudor","family":"Turcu","sequence":"additional","affiliation":[{"name":"Department of Pathology and Molecular Biology, Pathoteam Diagnostic, 051923 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelian Mihai","family":"Ghita","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandu-Dumitru","family":"Ramboiu","sequence":"additional","affiliation":[{"name":"Department of Surgery I, Clinical County Hospital, 200642 Craiova, Romania"},{"name":"Faculty of Medicine, University of Medicine and Pharmacy, 200349 Craiova, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandru","family":"Ciobanu","sequence":"additional","affiliation":[{"name":"Department of Radiology, SPAD Imaging, 200352 Craiova, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Visan","sequence":"additional","affiliation":[{"name":"Medical Oncology Department, OncoClinic Consult, 200094 Craiova, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"101990","DOI":"10.1016\/j.ijgc.2025.101990","article-title":"Mesonephric-like Adenocarcinoma of the Ovary: Features of a Rare and Aggressive Entity Associated with Endometriosis","volume":"36","author":"Mezzapesa","year":"2026","journal-title":"Int. J. Gynecol. Cancer"},{"key":"ref_2","unstructured":"Organisation Mondiale de la Sant\u00e9, and Centre International de Recherche sur le Cancer (2020). Female Genital Tumours, International Agency for Research on Cancer. [5th ed.]."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/PGP.0000000000001150","article-title":"Mesonephric-like Adenocarcinoma (MLA) Diagnostic Criteria and Controversies: Perspectives and Guidance from Pathologists in the MLA Consortium","volume":"45","author":"Mills","year":"2026","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"156110","DOI":"10.1016\/j.prp.2025.156110","article-title":"Clinical and Pathological Analysis of 17 Cases of Mesonephric-like Adenocarcinoma","volume":"273","author":"Kang","year":"2025","journal-title":"Pathol.-Res. Pract."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1111\/his.12895","article-title":"Hormone Receptor-negative, Thyroid Transcription Factor 1-positive Uterine and Ovarian Adenocarcinomas: Report of a Series of Mesonephric-like Adenocarcinomas","volume":"68","author":"McFarland","year":"2016","journal-title":"Histopathology"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1177\/10668969251331186","article-title":"Ovarian Mesonephric-Like Adenocarcinoma Arising Within a Serous Borderline Tumor: Insights into the Implications of Cell Origin\u2014A Case Report and Review of the Literature","volume":"33","author":"Chang","year":"2025","journal-title":"Int. J. Surg. Pathol."},{"key":"ref_7","first-page":"53","article-title":"Mesonephric-like Adenocarcinoma with Borderline Tumor in Ovary: A Case Report and Literature Review","volume":"49","author":"Zhang","year":"2022","journal-title":"J. Int. Obstet. Gynecol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1097\/PGP.0000000000000573","article-title":"Ovarian Combined Low-Grade Serous and Mesonephric-like Adenocarcinoma: Further Evidence for A Mullerian Origin of Mesonephric-like Adenocarcinoma","volume":"39","author":"McCluggage","year":"2020","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/PGP.0000000000000868","article-title":"Ovarian Combined Serous Borderline Tumor\/Low-Grade Serous Carcinoma and Mesonephric-like Lesion: Report of 2 Cases with New Observations","volume":"42","author":"Nilforoushan","year":"2023","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"5107","DOI":"10.3390\/curroncol31090378","article-title":"Ovarian Mesonephric-like Adenocarcinoma: Its Prevalence in a Japanese High-Volume Cancer Center and a Literature Review on Therapeutic Targets","volume":"31","author":"Ogawa","year":"2024","journal-title":"Curr. Oncol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"e23450","DOI":"10.1097\/MD.0000000000023450","article-title":"Mesonephric-like Adenocarcinoma of the Ovary: A Case Report and a Review of the Literature","volume":"99","author":"Chen","year":"2020","journal-title":"Medicine"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"rjaf025","DOI":"10.1093\/jscr\/rjaf025","article-title":"Mesonephric-like Adenocarcinoma of the Ovary: A Case Study","volume":"2025","author":"Assila","year":"2024","journal-title":"J. Surg. Case Rep."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13048-024-01383-7","article-title":"Mesonephric-like Adenocarcinoma of the Ovary","volume":"17","author":"Yang","year":"2024","journal-title":"J. Ovarian Res."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/PGP.0000000000001154","article-title":"Expanded Histologic Lineage and Origin of Mesonephric-Like Adenocarcinoma: A Clinicopathologic Study of 9 Cases","volume":"45","author":"Shi","year":"2026","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Chandra, A., Crothers, B., Kurtycz, D., and Schmitt, F. (2020). Special Considerations for Peritoneal Washings. The International System for Serous Fluid Cytopathology, Springer International Publishing.","DOI":"10.1007\/978-3-030-53908-5"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"4490","DOI":"10.1111\/jog.15035","article-title":"Mesonephric-like Adenocarcinoma of the Ovary in an Elderly Woman: A Case Report and a Review of the Literature","volume":"47","author":"Ujita","year":"2021","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"ref_17","first-page":"e79780","article-title":"Diagnostic Imaging Characteristics of a Rare Primary Ovarian Mesonephric-Like Adenocarcinoma: A Case Report and Literature Review","volume":"17","author":"Suzuki","year":"2025","journal-title":"Cureus"},{"key":"ref_18","first-page":"e94394","article-title":"Two Cases of Mesonephric-Like Adenocarcinoma Arising from Ovary and Peritoneal and Literature Review","volume":"17","author":"Sano","year":"2025","journal-title":"Cureus"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e12389","DOI":"10.1002\/2056-4538.12389","article-title":"Mesonephric-type Adenocarcinomas of the Ovary: Prevalence, Diagnostic Reproducibility, Outcome, and Value of PAX2","volume":"10","author":"Kang","year":"2024","journal-title":"J. Pathol. Clin. Res."},{"key":"ref_20","first-page":"114","article-title":"Mesonephric Carcinoma and Mesonephric-like Adenocarcinoma of the Female Genital Tract","volume":"5","author":"Hou","year":"2025","journal-title":"J. Clin. Transl. Pathol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/his.15312","article-title":"Identifying Mesonephric-like Adenocarcinoma of the Endometrium by Combining SOX17 and PAX8 Immunohistochemistry","volume":"86","author":"Tahir","year":"2025","journal-title":"Histopathology"},{"key":"ref_22","first-page":"100355","article-title":"Mesonephric-like Adenocarcinoma of the Ovary: A Rare Case Report and Review of the Literature","volume":"17","author":"Hosseinirad","year":"2025","journal-title":"Curr. Probl. Cancer Case Rep."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"112106","DOI":"10.1016\/j.ijscr.2025.112106","article-title":"Ovarian Mesonephric-like Adenocarcinoma Mimicking Serous Carcinoma: A Case Report Integrating Cytologic, Frozen, Histological, Immunohistochemistry, and Molecular Analyses","volume":"137","author":"Lin","year":"2025","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1097\/PGP.0000000000001118","article-title":"Napsin-A Expression in Mesonephric and Mesonephric-like Adenocarcinomas: Implications for Distinction from Clear Cell Carcinoma","volume":"44","author":"Mirkovic","year":"2025","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_25","first-page":"593","article-title":"Napsin-A and AMACR Are Superior to HNF-1\u03b2 in Distinguishing Between Mesonephric Carcinomas and Clear Cell Carcinomas of the Gynecologic Tract","volume":"28","author":"Pors","year":"2020","journal-title":"Appl. Immunohistochem. Mol. Morphol. AIMM"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/PGP.0000000000000991","article-title":"Ovarian Mesonephric-like Adenocarcinoma Recurring with a Rhabdomyosarcoma Component: A Case Report","volume":"43","author":"Yamamoto","year":"2024","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/his.14892","article-title":"Mesonephric-like Adenocarcinoma of the Female Genital Tract: Novel Observations and Detailed Molecular Characterisation of Mixed Tumours and Mesonephric-like Carcinosarcomas","volume":"82","author":"Mirkovic","year":"2023","journal-title":"Histopathology"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/PGP.0000000000000997","article-title":"Synchronous Bilateral Ovarian Mesonephric-like Adenocarcinomas with Separate Origins from High-Grade Mullerian Adenosarcoma and Endometriosis: Report of a Rare Case","volume":"43","author":"Zhao","year":"2024","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1186\/s13000-020-01012-z","article-title":"Ovarian Mesonephric-like Adenocarcinoma Arising in Serous Borderline Tumor: A Case Report with Complex Morphological and Molecular Analysis","volume":"15","author":"Dundr","year":"2020","journal-title":"Diagn. Pathol."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1038\/s41379-021-00799-6","article-title":"Mesonephric and Mesonephric-like Carcinomas of the Female Genital Tract: Molecular Characterization Including Cases with Mixed Histology and Matched Metastases","volume":"34","author":"Fix","year":"2021","journal-title":"Mod. Pathol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/PGP.0000000000000444","article-title":"Lastra An Ovarian Adenocarcinoma with Combined Low-Grade Serous and Mesonephric Morphologies Suggests a M\u00fcllerian Origin for Some Mesonephric Carcinomas","volume":"37","author":"Chapel","year":"2018","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1097\/PAS.0000000000002573","article-title":"Ovarian Mucinous Neoplasms Associated with Mesonephric-like Lesions: An Updated Study with Novel Pathologic Features","volume":"50","author":"Smith","year":"2026","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/j.pathol.2026.01.154","article-title":"Mixed Ovarian Mesonephric-like Adenocarcinoma, Mucinous Carcinoma and Endometrioid Carcinoma: A Case Report","volume":"58","author":"Zhu","year":"2026","journal-title":"Pathology"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1111\/jog.15539","article-title":"Synchronous Ovarian and Uterine Mesonephric-like Carcinoma That Potentially Arose from Endometrioid Adenofibroma: A Case Report","volume":"49","author":"Ishida","year":"2023","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1177\/10668969251333437","article-title":"Ovarian Mesonephric-Like Adenocarcinoma Arising from an Endometriotic Cyst with an Identical KRAS Mutation in Both Components: A Case Report","volume":"33","author":"Eto","year":"2025","journal-title":"Int. J. Surg. Pathol."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"100856","DOI":"10.1016\/j.gore.2021.100856","article-title":"The Similarities and Differences between Mesonephric Carcinoma and Mesonephric-like Carcinoma: Two Cases","volume":"37","author":"Kulkarni","year":"2021","journal-title":"Gynecol. Oncol. Rep."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"100657","DOI":"10.1016\/j.gore.2020.100657","article-title":"Mesonephric-like Adenocarcinoma of the Ovary with Co-Existent Endometriosis: A Case Report and Review of the Literature","volume":"34","author":"Seay","year":"2020","journal-title":"Gynecol. Oncol. Rep."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1177\/10668969261437122","article-title":"Peritoneal Mesonephric-Like Adenocarcinoma Arising in Endometriosis: Case Report and Review of the Literature Expanding the Spectrum of Extrauterine Mesonephric-Like Adenocarcinomas","volume":"34","author":"Mohamed","year":"2026","journal-title":"Int. J. Surg. Pathol."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1177\/10668969231183631","article-title":"Ovarian Mesonephric-Like Adenocarcinoma with Recurrent Liver Metastases: A Case Report with Analysis of Therapeutic Molecular Targets","volume":"32","author":"Sugitani","year":"2024","journal-title":"Int. J. Surg. Pathol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1097\/PAS.0000000000002039","article-title":"Extrauterine Mesonephric-like Carcinoma: A Comprehensive Single Institution Study of 33 Cases","volume":"47","author":"Euscher","year":"2023","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"100652","DOI":"10.1016\/j.gore.2020.100652","article-title":"Molecular Profiling of Mesonephric and Mesonephric-like Carcinomas of Cervical, Endometrial and Ovarian Origin","volume":"34","author":"Lin","year":"2020","journal-title":"Gynecol. Oncol. Rep."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"101049","DOI":"10.1016\/j.gore.2022.101049","article-title":"Somatic Mutation Analysis of Mesonephric-Like Adenocarcinoma and Associated Putative Precursor Lesions: Insight into Pathogenesis and Potential Molecular Treatment Targets","volume":"42","author":"Arslanian","year":"2022","journal-title":"Gynecol. Oncol. Rep."},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Koh, H.H., Park, E., and Kim, H.-S. (2022). Mesonephric-like Adenocarcinoma of the Ovary: Clinicopathological and Molecular Characteristics. Diagnostics, 12.","DOI":"10.3390\/diagnostics12020326"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"15727","DOI":"10.1007\/s00432-023-05306-9","article-title":"Mesonephric-like Adenocarcinoma of the Female Genital Tract: Possible Role of KRAS-Targeted Treatment\u2014Detailed Molecular Analysis of a Case Series and Review of the Literature for Targetable Somatic KRAS-Mutations","volume":"149","author":"Brambs","year":"2023","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/PAS.0000000000000958","article-title":"Targeted Genomic Profiling Reveals Recurrent KRAS Mutations in Mesonephric-like Adenocarcinomas of the Female Genital Tract","volume":"42","author":"Mirkovic","year":"2018","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.ygyno.2024.01.015","article-title":"Mesonephric and Mesonephric-like Adenocarcinomas of Gynecologic Origin: A Single-Center Experience with Molecular Characterization, Treatment, and Oncologic Outcomes","volume":"182","author":"Praiss","year":"2024","journal-title":"Gynecol. Oncol."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Qin, L., Lin, W., Zhou, X., Li, J., Zheng, W., Wang, Y., and Zhou, F. (2025). Cytopathologic Features of Mesonephric-like Adenocarcinoma in the Endometrium and Ovary: Eight Cases and Literature Review. Virchows Arch., 1\u201313.","DOI":"10.1007\/s00428-025-04353-6"},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"e27174","DOI":"10.1097\/MD.0000000000027174","article-title":"Mesonephric Adenocarcinomas in Female Genital Tract: A Case Series","volume":"100","author":"Xie","year":"2021","journal-title":"Medicine"},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"101638","DOI":"10.1016\/j.ijgc.2025.101638","article-title":"Controversies in the Management of Mesonephric and Mesonephric-Like Adenocarcinomas of the Female Genital Tract","volume":"35","author":"Praiss","year":"2025","journal-title":"Int. J. Gynecol. Cancer"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.yao.2023.01.004","article-title":"Mitogen-Activated Protein Kinase Driven Rare Gynecologic Cancers and Evolving Therapeutic Targets","volume":"3","author":"Grisham","year":"2023","journal-title":"Adv. Oncol."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s00432-019-03123-7","article-title":"Mesonephric-like Adenocarcinomas of the Uterine Corpus: Report of a Case Series and Review of the Literature Indicating Poor Prognosis for This Subtype of Endometrial Adenocarcinoma","volume":"146","author":"Horn","year":"2020","journal-title":"J. Cancer Res. Clin. Oncol."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/PGP.0000000000001187","article-title":"HER2 and FOLR1 Expression in Mesonephric and Mesonephric-Like Adenocarcinomas in the Gynecologic Tract","volume":"45","author":"Alzayadneh","year":"2026","journal-title":"Int. J. Gynecol. Pathol."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"101670","DOI":"10.1016\/j.gore.2024.101670","article-title":"Molecular Characterization of Ovarian Mesonephric-like Adenocarcinoma: Insights from Single-Cell RNA Sequencing and Mitochondrial Metabolism","volume":"57","author":"Han","year":"2025","journal-title":"Gynecol. Oncol. Rep."},{"key":"ref_54","first-page":"e95530","article-title":"Patient-Derived Xenograft Mouse Model of a Rare Gynecologic Malignancy: Personalized Medicine for the Treatment of Mesonephric-Like Adenocarcinoma","volume":"17","author":"Kasuya","year":"2025","journal-title":"Cureus"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/PAS.0000000000001612","article-title":"Clinicopathologic Characteristics of Mesonephric Adenocarcinomas and Mesonephric-like Adenocarcinomas in the Gynecologic Tract: A Multi-Institutional Study","volume":"45","author":"Pors","year":"2021","journal-title":"Am. J. Surg. Pathol."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1177\/10668969251382744","article-title":"Lung Metastatic Recurrence as Carcinosarcoma from Ovarian Mesonephric-Like Adenocarcinoma: A Case Report","volume":"34","author":"Nakama","year":"2026","journal-title":"Int. J. Surg. Pathol."}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/19\/3099\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:29:22Z","timestamp":1790245762000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/19\/3099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,24]]},"references-count":56,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2026,10]]}},"alternative-id":["diagnostics16193099"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics16193099","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,24]]}}}