{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:56:26Z","timestamp":1791222986212,"version":"4.1.0"},"reference-count":17,"publisher":"MDPI AG","issue":"19","license":[{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Background\/Objectives: Bowel resection is often required for complete cytoreduction in advanced ovarian cancer, and some units perform upper gastrointestinal endoscopy and colonoscopy beforehand. We compared the endoscopic biopsy findings with the histopathology of the resected bowel and examined determinants of survival. Methods: Eighty-three consecutive women with FIGO stage III\u2013IV serous ovarian cancer cytoreduced to no macroscopic residual disease between 2015 and 2021 were reviewed retrospectively; all had undergone both examinations and completed adjuvant carboplatin\u2013paclitaxel. Results: Bowel resection was performed in 20 women (24.1%). Serosal involvement was reported in 15 specimens and no tumour in four; mucosal invasion was reported in none (95% CI 0\u201316.8%). Eighteen patients (21.7%) were biopsied endoscopically; no biopsy was malignant. Over a median follow-up of 72 months, 50 women (60.2%) developed recurrence (28 confirmed histologically and 22 diagnosed from imaging and CA-125; recurrence was ascertained retrospectively, which limits the interpretation of disease-free survival) and 44 (53.0%) died. Recurrence was no more frequent in biopsied than in non-biopsied patients (8\/18 vs. 42\/65, p = 0.174) or after resection (10\/20 vs. 40\/63, p = 0.306). Age showed an exploratory association with disease-free (HR 1.03\/year, 95% CI 1.00\u20131.06) and overall survival (HR 1.04, 1.00\u20131.07). Conclusions: In this cohort, no preoperative endoscopic biopsy was malignant and no resected specimen was reported to show mucosal invasion, supporting a limited role for routine endoscopy in assessing bowel wall involvement; its diagnostic accuracy and its value for excluding a gastrointestinal primary could not be assessed.<\/jats:p>","DOI":"10.3390\/diagnostics16193221","type":"journal-article","created":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:30:07Z","timestamp":1791221407000},"page":"3221","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Can Routine Preoperative Endoscopy and Colonoscopy Be Meaningful for the Surgery and Postoperative Course of Patients with Advanced Ovarian Cancer? A Single-Centre Retrospective Cohort Study"],"prefix":"10.3390","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-6394-3638","authenticated-orcid":false,"given":"G\u00f6kt\u00fcrk Han","family":"Do\u011fan","sequence":"first","affiliation":[{"name":"Department of Gynecologic Oncology, \u0130zmir Tepecik Training and Research Hospital, University of Health Sciences, 35020 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0648-7767","authenticated-orcid":false,"given":"G\u00f6ksever","family":"Akp\u0131nar","sequence":"additional","affiliation":[{"name":"Department of General Surgery, \u0130zmir Tepecik Training and Research Hospital, University of Health Sciences, 35020 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6559-7002","authenticated-orcid":false,"given":"An\u0131l Do\u011fukan","family":"Tutal","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology, \u0130zmir Tepecik Training and Research Hospital, University of Health Sciences, 35020 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6013-6602","authenticated-orcid":false,"given":"Ceren","family":"Sa\u011flam Purut","sequence":"additional","affiliation":[{"name":"Department of Perinatology, \u0130zmir Atat\u00fcrk Training and Research Hospital, 35360 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ay\u015fe Berin","family":"Acar","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology, \u0130zmir Tepecik Training and Research Hospital, University of Health Sciences, 35020 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3187-2317","authenticated-orcid":false,"given":"Mehmet","family":"G\u00f6k\u00e7\u00fc","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology, Medical Point Hospital, \u0130zmir University of Economics, 35575 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-3593-6628","authenticated-orcid":false,"given":"Serhat","family":"Sar\u0131kaya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, \u0130zmir Tepecik Training and Research Hospital, University of Health Sciences, 35020 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunus Emre","family":"Purut","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology, \u0130zmir Tepecik Training and Research Hospital, University of Health Sciences, 35020 Izmir, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,10,5]]},"reference":[{"key":"ref_1","first-page":"e70090","article-title":"Global cancer statistics 2024: GLOBOCAN estimates of incidence and mortality worldwide for 34 cancers in 186 countries","volume":"76","author":"Sung","year":"2026","journal-title":"CA Cancer J. 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Cancer"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/19\/3221\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:30:22Z","timestamp":1791221422000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/16\/19\/3221"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,5]]},"references-count":17,"journal-issue":{"issue":"19","published-online":{"date-parts":[[2026,10]]}},"alternative-id":["diagnostics16193221"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics16193221","relation":{},"ISSN":["2075-4418"],"issn-type":[{"value":"2075-4418","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,5]]}}}