{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T16:13:17Z","timestamp":1761581597629,"version":"build-2065373602"},"reference-count":5,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T00:00:00Z","timestamp":1503619200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>We present a case demonstrating the diagnostic work-up and follow-up of a patient with Chikungunya infection. An 18F-FDG PET\/CT performed four weeks after debut of symptoms revealed pathological 18F-FDG uptake in enlarged lymph nodes on both side of the diaphragm, and inflammation of both shoulder and hip joints. Lymphoma and infection were the main differential diagnoses. Follow-up 18F-FDG PET\/CT scan in the patient performed 14 weeks after the abnormal scan, revealed almost complete resolution of the metabolically active disease. This case is to our knowledge the first to demonstrate sequential 18F-FDG PET\/CT scan results in a patient with Chikungunya virus infection.<\/jats:p>","DOI":"10.3390\/diagnostics7030049","type":"journal-article","created":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T11:03:17Z","timestamp":1503658997000},"page":"49","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["18F-FDG PET\/CT Findings in a Patient with Chikungunya Virus Infection"],"prefix":"10.3390","volume":"7","author":[{"given":"Michala","family":"Rose","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Copenhagen University Hospital Hvidovre, Kettegaard All\u00e9 30, Hvidovre DK-2650, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3623-7635","authenticated-orcid":false,"given":"Anna","family":"Kjaer","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Copenhagen University Hospital Hvidovre, Kettegaard All\u00e9 30, Hvidovre DK-2650, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Markova","sequence":"additional","affiliation":[{"name":"Department of Radiology, Copenhagen University Hospital Hvidovre, Kettegaard All\u00e9 30, Hvidovre DK-2650, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesper","family":"Graff","sequence":"additional","affiliation":[{"name":"Department of Clinical Physiology & Nuclear Medicine, Copenhagen University Hospital Hvidovre, Kettegaard All\u00e9 30, Hvidovre DK-2650, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2017,8,25]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1089\/vbz.2014.1680","article-title":"Updates on Chikungunya epidemiology, clinical disease, and diagnostics","volume":"15","author":"Sam","year":"2015","journal-title":"Vector Borne Zoonotic Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1172\/JCI84417","article-title":"Chikungunya virus: Epidemiology, replication, disease mechanisms, and prospective intervention strategies","volume":"127","author":"Silva","year":"2017","journal-title":"J. Clin. Investig."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1080\/02841860802637773","article-title":"A suspicion of Chikungunya leading to a diagnosis of angioimmunoblastic T-cell lymphoma","volume":"48","author":"Braiteh","year":"2009","journal-title":"Acta Oncol."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1097\/RLU.0000000000001110","article-title":"Increased 18F-FDG Uptake in the Spleen and Multiple Lymph Nodes in Dengue Fever","volume":"41","author":"Jinguji","year":"2016","journal-title":"Clin. Nucl. Med."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"e93474","DOI":"10.1172\/jci.insight.93474","article-title":"18F-FDG as an inflammation biomarker for imaging dengue virus infection and treatment response","volume":"4","author":"Chacko","year":"2017","journal-title":"JCI Insight"}],"container-title":["Diagnostics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2075-4418\/7\/3\/49\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T18:43:18Z","timestamp":1760208198000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2075-4418\/7\/3\/49"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,25]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,9]]}},"alternative-id":["diagnostics7030049"],"URL":"https:\/\/doi.org\/10.3390\/diagnostics7030049","relation":{},"ISSN":["2075-4418"],"issn-type":[{"type":"electronic","value":"2075-4418"}],"subject":[],"published":{"date-parts":[[2017,8,25]]}}}