{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T13:54:20Z","timestamp":1790171660835,"version":"4.1.0"},"reference-count":112,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2018,6,2]],"date-time":"2018-06-02T00:00:00Z","timestamp":1527897600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["14\/IA\/2646"],"award-info":[{"award-number":["14\/IA\/2646"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002081","name":"Irish Research Council","doi-asserted-by":"publisher","award":["GOIPG\/2014\/165"],"award-info":[{"award-number":["GOIPG\/2014\/165"]}],"id":[{"id":"10.13039\/501100002081","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Cancer is the cause of death for one in seven individuals worldwide. It is widely acknowledged that screening and early diagnosis are of vital importance for improving the likelihood of recovery. However, given the costly, time-consuming, and invasive nature of the many methods currently in use, patients often do not take advantage of the services available to them. Consequently, many researchers are exploring the possibility of developing fast, reliable, and non-invasive diagnostic tools that can be used directly or by local physicians at the point-of-care. Herein, we look at the use of established biomarkers in cancer therapy and investigate emerging biomarkers exhibiting future potential. The incorporation of these biomarkers into point-of-care devices could potentially reduce the strain currently experienced by screening programs in hospitals and healthcare systems. Results derived from point-of-care tests should be accurate, sensitive, and generated rapidly to assist in the selection of the best course of treatment for optimal patient care. Essentially, point-of-care diagnostics should enhance the well-being of patients and lead to a reduction in cancer-related deaths.<\/jats:p>","DOI":"10.3390\/diagnostics8020039","type":"journal-article","created":{"date-parts":[[2018,6,4]],"date-time":"2018-06-04T08:40:39Z","timestamp":1528101639000},"page":"39","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":95,"title":["Developments in Point-of-Care Diagnostic Technology for Cancer Detection"],"prefix":"10.3390","volume":"8","author":[{"given":"Bryony","family":"Hayes","sequence":"first","affiliation":[{"name":"Translational Health Sciences, Bristol Medical School, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0960-6677","authenticated-orcid":false,"given":"Caroline","family":"Murphy","sequence":"additional","affiliation":[{"name":"School of Biotechnology, Dublin City University, Collins Avenue, Glasnevin, Dublin D09 Y5N0, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aoife","family":"Crawley","sequence":"additional","affiliation":[{"name":"School of Biotechnology, Dublin City University, Collins Avenue, Glasnevin, Dublin D09 Y5N0, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"O\u2019Kennedy","sequence":"additional","affiliation":[{"name":"School of Biotechnology, Dublin City University, Collins Avenue, Glasnevin, Dublin D09 Y5N0, Ireland"},{"name":"Hamad Bin Khalifa University, Research Complex, P.O. Box 34110 Doha, Qatar"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,6,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.tibtech.2014.01.003","article-title":"Point-of-care technologies for molecular diagnostics using a drop of blood","volume":"32","author":"Song","year":"2014","journal-title":"Trends Biotechnol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"7775","DOI":"10.1007\/s00216-016-9879-z","article-title":"An integrated lab-on-a-chip-based electrochemical biosensor for rapid and sensitive detection of cancer biomarkers","volume":"408","author":"Uludag","year":"2016","journal-title":"Anal. Bioanal. 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