{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T18:20:42Z","timestamp":1789150842471,"version":"build-2803163510"},"reference-count":25,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T00:00:00Z","timestamp":1568764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad Cat\u00f3lica de Guayaquil, Ecuador","award":["grant No SIU- 319:"],"award-info":[{"award-number":["grant No SIU- 319:"]}]},{"name":"National Research Foundation of South Africa","award":["89230 and 98217"],"award-info":[{"award-number":["89230 and 98217"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diagnostics"],"abstract":"<jats:p>Somatosensory evoked potentials (SSEPs) are a valuable tool to assess functional integrity of the somatosensory pathways and for the prediction of sensorimotor outcome in perinatal injuries, such as perinatal hypoxia-ischemia (HI). In the present research, we studied the translational potential of SSEPs together with sensory function in the male adult rat with perinatal HI compared to the male healthy adult rat. Both somatosensory response and evoked potential were measured at 10-11 months after global perinatal HI. Clear evoked potentials were obtained, but there were no group differences in the amplitude or latency of the evoked potentials of the preceding sensory response. The bilateral tactile stimulation test was also normal in both groups. This lack of effect may be ascribed to the late age-of-testing and functional recovery of the rats.<\/jats:p>","DOI":"10.3390\/diagnostics9030123","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T04:26:46Z","timestamp":1568780806000},"page":"123","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Preterm Perinatal Hypoxia-Ischemia Does not Affect Somatosensory Evoked Potentials in Adult Rats"],"prefix":"10.3390","volume":"9","author":[{"given":"Melinda","family":"Barkhuizen","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Maastricht University Medical Centre (MUMC), 6229HX, Maastricht, The Netherlands"},{"name":"Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 HX, Maastricht, The Netherlands"},{"name":"DST\/NWU Preclinical Drug Development Platform, North-West University, Potchefstroom 2531, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan S.H.","family":"Vles","sequence":"additional","affiliation":[{"name":"Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 HX, Maastricht, The Netherlands"},{"name":"Child Neurology, Maastricht University Medical Centre, 6229 HX, Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"van Mechelen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Maastricht University Medical Centre (MUMC), 6229HX, Maastricht, The Netherlands"},{"name":"Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 HX, Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijne","family":"Vermeer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Maastricht University Medical Centre (MUMC), 6229HX, Maastricht, The Netherlands"},{"name":"Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 HX, Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris W.","family":"Kramer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Maastricht University Medical Centre (MUMC), 6229HX, Maastricht, The Netherlands"},{"name":"Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 HX, Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Chedraui","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n e Innovaci\u00f3n de Salud Integral, Facultad de Ciencias M\u00e9dicas, Universidad Cat\u00f3lica de Santiago de Guayaquil, Guayaquil 090615, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Bergs","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology, Maastricht University Medical Centre, 6229 HX Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivianne H.J.M.","family":"van Kranen-Mastenbroek","sequence":"additional","affiliation":[{"name":"Clinical Neurophysiology, Maastricht University Medical Centre, 6229 HX Maastricht, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio W.D.","family":"Gavilanes","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Maastricht University Medical Centre (MUMC), 6229HX, Maastricht, The Netherlands"},{"name":"Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNs), Maastricht University, 6229 HX, Maastricht, The Netherlands"},{"name":"Instituto de Investigaci\u00f3n e Innovaci\u00f3n de Salud Integral, Facultad de Ciencias M\u00e9dicas, Universidad Cat\u00f3lica de Santiago de Guayaquil, Guayaquil 090615, Ecuador"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.pediatrneurol.2009.12.007","article-title":"Neonatal Somatosensory Evoked Potentials: Maturational Aspects and Prognostic Value","volume":"42","author":"Trollmann","year":"2010","journal-title":"Pediatr. 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