{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T04:34:44Z","timestamp":1760243684997,"version":"build-2065373602"},"reference-count":13,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T00:00:00Z","timestamp":1663804800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Facial hemiplegia happens when the seventh cranial nerve is inflamed, causing a dysfunction of the facial nerve in specific regions. This case report brings a complex case of facial hemiplegia, a non-temporary lesion caused by a traumatic accident, which had a more conservative approach, treating the patient with botulinum toxin. After explanation of treatment outcomes, the patient favored treatment on a unilateral side with botulinum toxin applied locally to the muscles. It was applied on her left side, in order to change the muscles tonus and improve the esthetic. The patient adhered to immediate and short-term instructions following the procedure, including movement limitation and skin exposure avoidance. At 2 weeks, the patient returned to follow-up, and the result was checked. After around 6-month follow-up, the patient was reassessed, and a new application was done. The patient tried to contract the procerus and corrugator muscles which were treated, and periorbicular region that was corrected. After contracting the frontal muscle, a satisfactory result was also seen in the frontal area. While limited to a single case presentation, botulinum toxin may be an effective short-term tool for treatment of facial hemiplegia to establish an effective esthetic result.<\/jats:p>","DOI":"10.3390\/diseases10040067","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T21:10:05Z","timestamp":1663881005000},"page":"67","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Facial Hemiplegia Treated with Botulinum Toxin: A Case Report"],"prefix":"10.3390","volume":"10","author":[{"given":"Dem\u00e9trio","family":"Ajuz","sequence":"first","affiliation":[{"name":"Implant Dentistry, Rio de Janeiro 22031-071, Brazil"},{"name":"Brazilian Academy of Dentistry (AcBO), Rio de Janeiro 22031-071, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro D.","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Department of Physiology, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Ribeir\u00e3o Preto 21710-232, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7603-3544","authenticated-orcid":false,"given":"Juliana Campos Hasse","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Private Office, Ann Arbor, MI 48109, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3022-4390","authenticated-orcid":false,"given":"Gustavo Vicentis de Oliveira","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Brazilian Academy of Dentistry (AcBO), Rio de Janeiro 22031-071, Brazil"},{"name":"Periodontics and Oral Medicine Department, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,9,22]]},"reference":[{"key":"ref_1","unstructured":"Blumenfeld, H. 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Surg."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.fsc.2004.04.008","article-title":"Complications of botulinum toxin A use in facial rejuvenation","volume":"13","author":"Vartanian","year":"2005","journal-title":"Facial Plast Surg. Clin. North. Am."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1038\/jid.2012.60","article-title":"Botulinum neurotoxin A decreases infiltrating cutaneous lymphocytes and improves acanthosis in the KC-Tie2 mouse model","volume":"137","author":"Ward","year":"2012","journal-title":"J. Investig. Dermatol."},{"key":"ref_13","first-page":"168","article-title":"Botulinum toxin injection for facial wrinkles","volume":"90","author":"Small","year":"2014","journal-title":"Am. Fam. Physician"}],"container-title":["Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-9721\/10\/4\/67\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:37:26Z","timestamp":1760143046000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-9721\/10\/4\/67"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,22]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["diseases10040067"],"URL":"https:\/\/doi.org\/10.3390\/diseases10040067","relation":{},"ISSN":["2079-9721"],"issn-type":[{"type":"electronic","value":"2079-9721"}],"subject":[],"published":{"date-parts":[[2022,9,22]]}}}