{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:56:31Z","timestamp":1791849391614,"version":"4.3.4"},"reference-count":36,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T00:00:00Z","timestamp":1692316800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Diabetes mellitus (DM) is one of the world\u2019s most important health problems, affecting more than half a billion of the world\u2019s population today, with an ever-increasing prevalence. Among the most common manifestations of diabetes are skin manifestations, with 30\u201370% of patients experiencing skin complications during the course of the disease. Conditions such as acanthosis nigricans, diabetic dermopathy, necrobiosis lipoidica, bacterial infections, fungal infections, skin xerosis, and metabolic prurigo are often associated with diabetes and often precede its diagnosis. We conducted a retrospective study on a group of 103 patients hospitalized between January 2018 and December 2022, in a clinic of a county hospital, using as criteria the diagnosis of diabetes mellitus complicated by cutaneous manifestations frequently associated with diabetes. The aim was to observe which are the most common manifestations and whether they correlate with data in the research literature. In the present study, manifestations such as diabetic foot (20% of patients), bacterial (35%) and fungal infections, and cutaneous xerosis (45%) were predominant. Often, the integumentary involvement may precede the diagnosis of the underlying disease. It is therefore very important to recognize, investigate and treat these manifestations as soon as possible.<\/jats:p>","DOI":"10.3390\/diseases11030106","type":"journal-article","created":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T10:14:38Z","timestamp":1692353678000},"page":"106","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Cutaneous Manifestations Associated with Diabetes Mellitus\u2014A Retrospective Study"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2755-6004","authenticated-orcid":false,"given":"Dan","family":"V\u00e2\u021b\u0103","sequence":"first","affiliation":[{"name":"Department of Dermatology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"},{"name":"Dermatology Clinic, \u201cSt. Spiridon\u201d Emergency County Hospital, 700106 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana-Elena","family":"Stanciu","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, \u201cSt. Spiridon\u201d Emergency County Hospital, 700106 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doini\u021ba","family":"Temelie-Olinici","sequence":"additional","affiliation":[{"name":"Dermatology Clinic, \u201cSt. Spiridon\u201d Emergency County Hospital, 700106 Iasi, Romania"},{"name":"Department of Cell Biology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2859-2066","authenticated-orcid":false,"given":"Elena","family":"Porumb-Andrese","sequence":"additional","affiliation":[{"name":"Department of Dermatology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4075-5451","authenticated-orcid":false,"given":"Bogdan-Marian","family":"Tarc\u0103u","sequence":"additional","affiliation":[{"name":"Department of Dermatology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"},{"name":"Dermatology Clinic, \u201cSt. Spiridon\u201d Emergency County Hospital, 700106 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasile-Bogdan","family":"Grecu","sequence":"additional","affiliation":[{"name":"Department of Cell Biology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Gheuc\u0103-Solov\u0103stru","sequence":"additional","affiliation":[{"name":"Department of Dermatology, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy, 700115 Ia\u0219i, Romania"},{"name":"Dermatology Clinic, \u201cSt. Spiridon\u201d Emergency County Hospital, 700106 Iasi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,18]]},"reference":[{"key":"ref_1","doi-asserted-by":"publisher","first-page":"869","DOI":"10.1016\/j.ecl.2013.07.004","article-title":"Dermatologic manifestations of diabetes mellitus","volume":"42","author":"Han","year":"2013","journal-title":"Endocrinol. Metab. Clin."},{"key":"ref_2","doi-asserted-by":"publisher","first-page":"40","DOI":"10.2337\/diaclin.33.1.40","article-title":"Cutaneous manifestations of diabetes mellitus","volume":"33","author":"Duff","year":"2015","journal-title":"Clin. Diabetes"},{"key":"ref_3","first-page":"100","article-title":"Cutaneous Manifestation of Diabetes mellitus","volume":"9","author":"Garg","year":"2021","journal-title":"J. Adv. Med. Dent. Scie. 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