{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:27:15Z","timestamp":1792301235835,"version":"4.4.0"},"reference-count":45,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T00:00:00Z","timestamp":1705363200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Bronchiolitis is an acute viral infection of the lower respiratory tract that affects infants and young children. Respiratory syncytial virus (RSV) is the most common causative agent; however, other viruses can be involved in this disease. We retrospectively reviewed the clinical features of infants aged less than 12 months hospitalized for acute bronchiolitis in our Pediatric Units of Chivasso, Ciri\u00e9, and Ivrea in Piedmont, Northern Italy, over two consecutive bronchiolitis seasons (September 2021\u2013March 2022 and September 2022\u2013March 2023). Patient-, disease-, and treatment-related variables were analyzed. The probability of therapeutic success (discharge home) was 96% for all patients (93% for RSV vs. 98% for non-RSV patients, p &gt; 0.05). Among 192 patients, 42 infants (22%) underwent high-flow oxygen support (HFNC), and only 8 (4%) needed to be transferred to our hub referral hospital. Factors associated with hub hospital transfer were the age under 1 month and the failure of HFNC. The wide and increasing use of HFNC in pediatric inpatients improved the management of bronchiolitis in Spoke hospitals, reducing transfer to a hub hospital provided with Intensive Care Units.<\/jats:p>","DOI":"10.3390\/diseases12010025","type":"journal-article","created":{"date-parts":[[2024,1,16]],"date-time":"2024-01-16T11:37:18Z","timestamp":1705405038000},"page":"25","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Management of Acute Bronchiolitis in Spoke Hospitals in Northern Italy: Analysis and Outcome"],"prefix":"10.3390","volume":"12","author":[{"given":"Carla","family":"Guidi","sequence":"first","affiliation":[{"name":"Pediatrics Department, Ciri\u00e8 Hospital, 10073 Ciri\u00e8, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neftj","family":"Ragusa","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Ivrea Hospital, 10015 Ivrea, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilaria","family":"Mussinatto","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Chivasso Hospital, 10034 Chivasso, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Parola","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Ciri\u00e8 Hospital, 10073 Ciri\u00e8, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Luotti","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Ivrea Hospital, 10015 Ivrea, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Calosso","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Chivasso Hospital, 10034 Chivasso, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Rotondo","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Ciri\u00e8 Hospital, 10073 Ciri\u00e8, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Deut","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Ivrea Hospital, 10015 Ivrea, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Timeus","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Chivasso Hospital, 10034 Chivasso, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adalberto","family":"Brach del Prever","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Ciri\u00e8 Hospital, 10073 Ciri\u00e8, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3455-3802","authenticated-orcid":false,"given":"Massimo","family":"Berger","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Ivrea Hospital, 10015 Ivrea, TO, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,1,16]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1056\/NEJMra1413456","article-title":"Viral Bronchiolitis in Children","volume":"374","author":"Meissner","year":"2016","journal-title":"N. 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