{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T14:19:49Z","timestamp":1765808389300,"version":"build-2065373602"},"reference-count":18,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,8,17]],"date-time":"2024-08-17T00:00:00Z","timestamp":1723852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Background: developmental dysplasia of the hip (DDH) is a condition characterized by abnormal hip development in infancy. Early diagnosis allows for effective treatment, while late presentation often necessitates complex surgical interventions. Current recommendations advise screening between the 6th and 8th week postnatal using an ultrasound, typically employing the Graf method. However, there is no universal consensus on whether ultrasound screening significantly increases treatment likelihood compared to clinical examination-guided ultrasound. This study aims to explore the feasibility of prenatal ultrasound for the early identification of DDH risk. Methods: This prospective observational study involved 100 pregnant women undergoing fetal hip ultrasounds during the second and third trimesters. Using the modified Graf method, alpha and beta angles were calculated on the fetus. Postnatally, alpha and beta angles were compared with the prenatal values. Results: Prenatal ultrasound at the 24th week showed inconclusive results because of the difficulty in identification of Graf landmarks, while ultrasound at the 34th week proved to be a reliable and safe method for the quantitative determination of alpha and beta angles. Significant correlations were found between prenatal and postnatal alpha and beta angles. Moreover, significant differences in prenatal alpha and beta values were observed in patients developing mature\/immature hips postnatally. Conclusions: Prenatal diagnostics show promise for predicting infant hip development. Further research is warranted to validate correlation strength and clinical applicability.<\/jats:p>","DOI":"10.3390\/diseases12080188","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T03:43:28Z","timestamp":1724039008000},"page":"188","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Feasibility of Prenatal Ultrasonic Screening for Developmental Dysplasia of the Hip"],"prefix":"10.3390","volume":"12","author":[{"given":"Claudia","family":"Bevilacqua","sequence":"first","affiliation":[{"name":"Adult and Pediatric Orthopedic Clinic, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Via Conca 71, 60126 Torrette, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Boscarato","sequence":"additional","affiliation":[{"name":"Second-Level Prenatal Diagnosis, Ospedale di Comunit\u00e0 di Loreto, AST Ancona, Via F. D\u2019Assisi 1, 60025 Loreto, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Pieroni","sequence":"additional","affiliation":[{"name":"Radiological Sciences, SOD Radiologia Materno Infantile, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Via F. Corridoni 11, 60123 Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4838-3011","authenticated-orcid":false,"given":"Eva","family":"Fraternali","sequence":"additional","affiliation":[{"name":"Adult and Pediatric Orthopedic Clinic, Dip. Scienze Cliniche e Molecolari, Universit\u00e0 Politecnica delle Marche, Ancona, Via Conca 71, 60126 Torrette, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5742-8599","authenticated-orcid":false,"given":"Giuliano","family":"Lattanzi","sequence":"additional","affiliation":[{"name":"Adult and Pediatric Orthopedic Clinic, Dip. Scienze Cliniche e Molecolari, Universit\u00e0 Politecnica delle Marche, Ancona, Via Conca 71, 60126 Torrette, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone Domenico","family":"Aspriello","sequence":"additional","affiliation":[{"name":"ASD Dental Clinic, 61121 Pesaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio Pompilio","family":"Gigante","sequence":"additional","affiliation":[{"name":"Adult and Pediatric Orthopedic Clinic, Dip. Scienze Cliniche e Molecolari, Universit\u00e0 Politecnica delle Marche, Ancona, Via Conca 71, 60126 Torrette, Italy"},{"name":"INRCA, ICRS, via della Montagnola, 60127 Ancona, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Cecchi","sequence":"additional","affiliation":[{"name":"Second-Level Prenatal Diagnosis, Ospedale di Comunit\u00e0 di Loreto, AST Ancona, Via F. D\u2019Assisi 1, 60025 Loreto, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,17]]},"reference":[{"key":"ref_1","first-page":"CD012717","article-title":"Splinting for the non-operative management of developmental dysplasia of the hip (DDH) in children under six months of age","volume":"10","author":"Dwan","year":"2022","journal-title":"Cochrane Database Syst. Rev."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1136\/adc.60.5.407","article-title":"Congenital dislocation of the hip: Early and late diagnosis and management compared","volume":"60","author":"Dunn","year":"1985","journal-title":"Arch. Dis. Child."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Ning, B., Yuan, Y., Yao, J., Zhang, S., and Sun, J. (2014). Analyses of outcomes of one-stage operation for treatment of late-diagnosed developmental dislocation of the hip: 864 hips followed for 3.2 to 8.9 years. 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Turc."}],"container-title":["Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-9721\/12\/8\/188\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:38:16Z","timestamp":1760110696000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-9721\/12\/8\/188"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,17]]},"references-count":18,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["diseases12080188"],"URL":"https:\/\/doi.org\/10.3390\/diseases12080188","relation":{},"ISSN":["2079-9721"],"issn-type":[{"type":"electronic","value":"2079-9721"}],"subject":[],"published":{"date-parts":[[2024,8,17]]}}}