{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T09:49:14Z","timestamp":1776937754334,"version":"3.51.4"},"reference-count":35,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T00:00:00Z","timestamp":1775865600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Background\/Objective: The parotid gland is the largest salivary gland, and tumors arising from it exhibit wide histopathological diversity. Management approaches vary according to tumor characteristics and carry a risk of postoperative complications, particularly facial nerve injury. However, local data remain limited. This study aimed to describe the clinicopathological characteristics, surgical approaches, and postoperative outcomes of patients undergoing parotidectomy. Method: A retrospective cohort study was conducted at a high-volume tertiary center in Saudi Arabia. All consecutive patients who underwent parotidectomy between June 2015 and January 2025 were included. Demographic data, histopathological diagnoses, surgical procedures and postoperative complications were extracted from electronic medical records. Statistical analyses were performed using SPSS version 26, with A p-value of &lt;0.05 considered statistically significant. Results: A total of 154 patients were included, with a mean age of 45.2 \u00b1 12.6 years; 61% were male. Benign lesions constituted 87% of cases, with pleomorphic adenoma being the most common histopathological diagnosis. Malignancies accounted for 13% of cases, most frequently mucoepidermoid carcinoma. The most common postoperative complications were facial nerve palsy, followed by sensory numbness. Conclusions: The majority of parotid gland tumors in this cohort were benign, with pleomorphic adenoma as the most common histological subtype. Facial nerve palsy and sensory disturbances were the most common postoperative complications. These findings provide valuable local data on parotid gland lesions in Saudi Arabia and support current surgical management practices.<\/jats:p>","DOI":"10.3390\/diseases14040143","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T07:29:29Z","timestamp":1776065369000},"page":"143","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinicopathological Characteristics and Postoperative Outcomes Following Parotidectomy: A Ten-Year Retrospective Study from a Tertiary Center"],"prefix":"10.3390","volume":"14","author":[{"given":"Mohammad","family":"Aljarba","sequence":"first","affiliation":[{"name":"College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mishari","family":"Alanezi","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majed A.","family":"Alali","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azzam","family":"Alotaibi","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-8361-7897","authenticated-orcid":false,"given":"Faisal","family":"Alkhunein","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University, Riyadh 11411, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid","family":"Alqahtani","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, College of Medicine, King Saud University, P.O. Box 245, Riyadh 11411, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,11]]},"reference":[{"key":"ref_1","first-page":"154","article-title":"Epidemiological and clinical characteristics of 705 salivary gland neoplasms","volume":"67","year":"2013","journal-title":"Otolaryngol. Pol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.mpdhp.2020.01.001","article-title":"Salivary gland tumours: Diagnostic challenges and an update on the latest WHO classification","volume":"26","author":"Speight","year":"2020","journal-title":"Diagn. Histopathol."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"AlMaden, N., AlYami, R., Almotairi, A., Alrasheed, R., Aldawasri, B., Alwhabi, M., Alrumeh, A., AlBishi, N., Alqarni, A., and Alghamdi, D. (2024). Relative frequency of primary salivary gland tumors: Multicenter study of 796 cases from Riyadh, Saudi Arabia. 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