{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T05:05:45Z","timestamp":1779339945619,"version":"3.51.4"},"reference-count":20,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>The pancreatic pseudocyst is a collection of pancreatic fluid surrounded by a non-epithelialized wall comprising granulation tissue and fibrosis, occurring in approximately 10% of patients diagnosed with acute pancreatitis and in 20\u201338% of those with chronic pancreatitis. Most pseudocysts are situated in the pancreatic head and pancreatic body, but about 20% develop in extrapancreatic locations. We present the case of a 46-year-old male patient diagnosed with chronic alcohol pancreatitis with acute exacerbation, who developed a large pancreatic pseudocyst with subcapsular location in the right hepatic lobe; this was successfully treated by laparoscopic surgical drainage, with no postoperative complications and no recurrence of the pseudocyst. The computed tomography scan and postoperative biochemical analysis of the intracystic fluid played a key role in establishing the diagnosis of this rare condition. An intrahepatic pancreatic pseudocyst is a rare location for pancreatic pseudocysts, but one located in the right hepatic lobe is extremely rare. The treatment of intrahepatic pancreatic pseudocysts may be conservative, though endoscopic, percutaneous, or surgical drainage may be necessary. The presence of symptoms, signs of extrinsic compression, or complications require drainage of the pseudocyst. The \u201ctake-away\u201d lesson learned from this case: surgical treatment for pancreatic pseudocysts located subcapsularly in the liver may be considered when they are very large, or when minimally invasive treatment has not been effective.<\/jats:p>","DOI":"10.3390\/diseases14050174","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T14:19:29Z","timestamp":1778854769000},"page":"174","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Subcapsular Pancreatic Pseudocyst of the Right Hepatic Lobe: A Rare Case Report and Literature Review"],"prefix":"10.3390","volume":"14","author":[{"given":"Nutu","family":"Vlad","sequence":"first","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"},{"name":"Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurentiu","family":"Budaca","sequence":"additional","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2491-1661","authenticated-orcid":false,"given":"Alexandra","family":"Ciubotariu","sequence":"additional","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florina-Delia","family":"Andriesi-Rusu","sequence":"additional","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"},{"name":"Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mircea Florin","family":"Costache","sequence":"additional","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"},{"name":"Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gigel","family":"Sandu","sequence":"additional","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Cristea","sequence":"additional","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7074-5938","authenticated-orcid":false,"given":"C\u0103t\u0103lin","family":"Sfarti","sequence":"additional","affiliation":[{"name":"\u201dSaint Spiridon\u201d Hospital Iasi, 700111 Iasi, Romania"},{"name":"Faculty of Medicine, \u201cGrigore T. Popa\u201d University of Medicine and Pharmacy Iasi, 700115 Iasi, Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"616","DOI":"10.4321\/S1130-01082006000800007","article-title":"Pancreatic pseudocyst located in the liver","volume":"98","author":"Les","year":"2006","journal-title":"Rev. Esp. Enferm. Dig."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"4655","DOI":"10.3748\/wjg.v13.i34.4655","article-title":"Multiple intrahepatic pseudocysts in acute pancreatitis","volume":"13","author":"Casado","year":"2007","journal-title":"World J. Gastroenterol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"109125","DOI":"10.1016\/j.ijscr.2023.109125","article-title":"Intrahepatic pancreatic pseudocyst (wayward cyst): A rare presentation of traumatic pancreatitis","volume":"114","author":"Shrestha","year":"2024","journal-title":"Int. J. Surg. Case Rep."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"222","DOI":"10.15403\/jgld.2014.1121.263.pje","article-title":"Intrahepatic pancreatic pseudocyst: A rare case complication of pancreatitis","volume":"26","author":"Edmonds","year":"2017","journal-title":"J. Gastrointest. Liver Dis."},{"key":"ref_5","first-page":"801","article-title":"Pancreatic pseudocysts located in the liver: A systematic review of the literature","volume":"87","author":"Guesmi","year":"2009","journal-title":"Tunis. Medicale"},{"key":"ref_6","first-page":"225","article-title":"Spontaneous rupture of intrahepatic pseudocyst into the inferior vena cava","volume":"6","author":"Patidar","year":"2018","journal-title":"Gastroenterol. Rep."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"8476","DOI":"10.12998\/wjcc.v9.i28.8476","article-title":"Percutaneous drainage in the treatment of intrahepatic pancreatic pseudocyst with Budd-Chiari syndrome: A case report","volume":"9","author":"Zhu","year":"2021","journal-title":"World J. Clin. Cases"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s13256-023-03957-3","article-title":"Pancreatic pseudocyst mimicking a left kidney abscess: A case report","volume":"17","author":"Madani","year":"2023","journal-title":"J. Med. Case Rep."},{"key":"ref_9","first-page":"263","article-title":"Multiple intrahepatic pancreatic pseudocyst (MIHPPs): An overlooked and misdiagnosed entity","volume":"12","author":"Tomar","year":"2019","journal-title":"Gastroenterol. Hepatol. Bed Bench"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.4254\/wjh.v8.i35.1576","article-title":"Intrahepatic pancreatic pseudocyst: A review of the world literature","volume":"8","author":"Demeusy","year":"2016","journal-title":"World J. Hepatol."},{"key":"ref_11","first-page":"PD18","article-title":"A rare case report of a hepatic subcapsular pseudocyst of pancreas","volume":"10","author":"Topno","year":"2016","journal-title":"J. Clin. Diagn. Res."},{"key":"ref_12","first-page":"593","article-title":"An intra-hepatic pancreatic pseudocyst successfully treated endoscopic transpapillary drainage ale","volume":"6","author":"Bhasin","year":"2005","journal-title":"JOP"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e00507","DOI":"10.1016\/j.idcr.2019.e00507","article-title":"ERCP-associated infected intrahepatic pancreatic pseudocyst","volume":"15","author":"Angsubhakorn","year":"2019","journal-title":"IDCases"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1097\/00004836-200001000-00016","article-title":"Pancreatic pseudocyst located in the liver: A case report and literature review","volume":"30","author":"Mofredj","year":"2000","journal-title":"J. Clin. Gastroenterol."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","article-title":"Acute Pancreatitis Classification Working Group. Classification of acute pancreatitis\u20142012: Revision of the Atlanta classification and definitions by international consensus","volume":"62","author":"Banks","year":"2013","journal-title":"Gut"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"643","DOI":"10.2214\/AJR.07.2761","article-title":"MDCT of acute mild (nonnecrotizing) pancreatitis: Abdominal complications and fate of fluid collections","volume":"190","author":"Lenhart","year":"2008","journal-title":"Am. J. Roentgenol."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1053\/gast.1996.v111.pm8780582","article-title":"Endoscopic therapy for organized pancreatic necrosis","volume":"111","author":"Baron","year":"1996","journal-title":"Gastroenterology"},{"key":"ref_18","first-page":"178","article-title":"Pseudocyst drainage predisposes to infection when pancreatic necrosis is unrecognized","volume":"89","author":"Hariri","year":"1994","journal-title":"Am. J. Cholest."},{"key":"ref_19","first-page":"279","article-title":"Subacute pancreatic necrosis","volume":"42","author":"Petrakis","year":"2000","journal-title":"Panminerva Med."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/00006676-200303000-00001","article-title":"Atlanta redux","volume":"26","author":"Bradley","year":"2003","journal-title":"Pancreas"}],"container-title":["Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2079-9721\/14\/5\/174\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T04:11:31Z","timestamp":1779336691000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2079-9721\/14\/5\/174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,15]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2026,5]]}},"alternative-id":["diseases14050174"],"URL":"https:\/\/doi.org\/10.3390\/diseases14050174","relation":{},"ISSN":["2079-9721"],"issn-type":[{"value":"2079-9721","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,15]]}}}