{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T11:16:47Z","timestamp":1780917407403,"version":"3.54.1"},"reference-count":24,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T00:00:00Z","timestamp":1780876800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Background\/Objectives: Parents of children with autism spectrum disorder (ASD) often face sustained emotional, practical, and social demands. However, evidence from Romania remains limited, particularly regarding the combined assessment of caregiver burden, emotional distress, and coping strategies of parents. This exploratory study compared these outcomes between parents of children\/adolescents with ASD and parents of typically developing children and examined whether coping patterns varied according to selected sociodemographic characteristics. Methods: We conducted a cross-sectional comparative study in T\u00e2rgu-Mure\u0219, Romania, between 2024 and 2025. The sample included 92 parents: 46 parents of children\/adolescents with clinician-confirmed ASD and 46 parents of typically developing children. Participants completed a demographic questionnaire, the Caregiver Burden Inventory (CBI), the Depression Anxiety Stress Scales-21 (DASS-21), and the Strategic Approach to Coping Scale (SACS). DASS-21 data were available for 44 ASD caregivers and 46 controls. Between-group comparisons were performed using t-tests, Mann\u2013Whitney U tests, chi-square tests, or Fisher\u2019s exact tests, as appropriate. Results: The groups were comparable in sex, age, residence, number of children, and household size, but differed significantly in marital status and educational level. Clinically relevant caregiver burden (CBI \u2265 36) was more frequent among parents of children with ASD than among controls (30% vs. 17%), although this difference was not statistically significant. Parents of children with ASD showed trend-level higher depressive and anxiety symptoms, with small effect sizes, whereas stress scores were similar between groups. Coping patterns varied according to sociodemographic characteristics. Marital status was associated with aggressive coping, urban residence was associated with indirect and aggressive coping, and number of children was associated with seeking social support. Conclusions: Parents of children with ASD showed a higher proportion of clinically relevant caregiver burden and trend-level elevations in depressive and anxiety symptoms, while stress scores were comparable between groups. Exploratory adjusted analyses suggested that ASD caregiver status remained associated with caregiver burden and depressive symptoms after controlling for educational level and marital status. Coping strategies appeared heterogeneous and context-dependent. Given the exploratory design, modest sample size, and multiple comparisons, these findings should be interpreted as preliminary and hypothesis-generating.<\/jats:p>","DOI":"10.3390\/diseases14060205","type":"journal-article","created":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T10:04:14Z","timestamp":1780913054000},"page":"205","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Caregiver Burden, Emotional Distress, and Coping Strategies in Romanian Parents of Children with Autism Spectrum Disorder: An Exploratory Cross-Sectional Comparative Study"],"prefix":"10.3390","volume":"14","author":[{"given":"Otilia-Rodica","family":"Butiu","sequence":"first","affiliation":[{"name":"Psychiatry Department, George Emil Palade University of Medicine, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"},{"name":"Neuropsychiatric Clinic, Mures County Hospital, 540005 Targu Mures, Romania"},{"name":"Institute of Psychotherapy and Personal Development, 540038 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ema","family":"Burlacu","sequence":"additional","affiliation":[{"name":"Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4856-2621","authenticated-orcid":false,"given":"Rebeca-Isabela","family":"Molnar","sequence":"additional","affiliation":[{"name":"Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"},{"name":"Psychiatric Clinic 1, Mures County Hospital, 540081 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Mihai","sequence":"additional","affiliation":[{"name":"Psychiatry Department, George Emil Palade University of Medicine, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"},{"name":"Institute of Psychotherapy and Personal Development, 540038 Targu Mures, Romania"},{"name":"Psychiatric Clinic 1, Mures County Hospital, 540081 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teodora","family":"Popescu","sequence":"additional","affiliation":[{"name":"Institute of Psychotherapy and Personal Development, 540038 Targu Mures, Romania"},{"name":"Doctoral School of Medicine and Pharmacy, George Emil Palade University of Medicine, Science, and Technology of Targu Mures, 540142 Targu Mures, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"43","DOI":"10.17159\/2310-3833\/2019\/vol49n1a7","article-title":"Parents\u2019 voices: Experiences and coping as a parent of a child with autism spectrum disorder","volume":"49","author":"Reddy","year":"2019","journal-title":"S. 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