{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:39:04Z","timestamp":1787027944319,"version":"build-2736575974"},"reference-count":27,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:00:00Z","timestamp":1781481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Background: Hydatid disease, caused primarily by Echinococcus granulosus, remains a significant public health challenge in endemic regions. While hepatic (80\u201385%) and pulmonary (15\u201320%) involvements are common, multi-organ dissemination involving rare sites such as the pericardium, diaphragm, and mediastinum occurs in less than 0.1\u20132% of cases. Case presentation: We present a rare case of a 26-year-old male, a farmer for 10 years, with occupational exposure to dogs and horses, with a personal history of multiple surgically treated abdominal cysts in 2016, admitted after abdominal computed tomography revealed liver cysts greater than 5 cm, as well as mediastinal and diaphragmatic cysts. Histopathological examination of the surgically resected hepatic cyst material confirmed echinococcosis. Serology was also positive for echinococcosis. Echocardiography revealed a pericardial cyst, posterior to the left atrium. Under these circumstances, antiparasitic treatment was initiated by an infectious disease specialist, followed by surgical treatment of the abdominal cysts, confirming the final diagnosis of hydatid disease, and subsequently, surgical treatment of the thoracic hydatid cysts was performed. The postoperative course was complicated by bronchial superinfection with Stenotrophomonas maltophilia, identified from bronchial aspirate culture after extended incubation and managed with trimethoprim\u2013sulfamethoxazole. Conclusions: This case underscores the necessity of lifelong surveillance in hydatid disease, the potential role of postoperative antiparasitic therapy in preventing long-term recurrence, and the vital role of a multidisciplinary team in managing complex, disseminated relapses.<\/jats:p>","DOI":"10.3390\/diseases14060215","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T08:57:58Z","timestamp":1781513878000},"page":"215","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Rare Case of Extensive Relapsing Disseminated Hydatid Disease with Multi-Organ Involvement: A Case Report"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3856-7917","authenticated-orcid":false,"given":"Silviu Gabriel","family":"Vl\u0103sceanu","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2334-9352","authenticated-orcid":false,"given":"Radu \u0218erban","family":"Matache","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"},{"name":"Thoracic Surgery I, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9240-922X","authenticated-orcid":false,"given":"Beatrice","family":"Mahler","sequence":"additional","affiliation":[{"name":"Department of Pneumology, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"},{"name":"Pneumoftisiology II Discipline, Faculty of Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9982-2618","authenticated-orcid":false,"given":"Alexandru","family":"Stoichi\u021b\u0103","sequence":"additional","affiliation":[{"name":"Department of Pneumology, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"},{"name":"Pneumoftisiology II Discipline, Faculty of Medicine, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6256-6312","authenticated-orcid":false,"given":"Camelia Alexandra","family":"Paruschi","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina Elena","family":"Tucana","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei Cristian","family":"Bobocea","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6419-7805","authenticated-orcid":false,"given":"Cornel Florentin","family":"Savu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, \u201cMarius Nasta\u201d National Institute of Pneumology, 050150 Bucharest, Romania"},{"name":"Thoracic Surgery I, University of Medicine and Pharmacy \u201cCarol Davila\u201d, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"8859116","DOI":"10.1155\/2020\/8859116","article-title":"Review on Epidemiology and Public Health Significance of Hydatidosis","volume":"2020","author":"Gessese","year":"2020","journal-title":"Vet. 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