{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:31:03Z","timestamp":1787679063515,"version":"build-2784847793"},"reference-count":21,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T00:00:00Z","timestamp":1535673600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Diseases"],"abstract":"<jats:p>Cryptococcal meningitis is a life-threatening condition caused by a fungal pathogen, Cryptococcus neoformans, that can infect both immunosuppressed and immunocompetent hosts. It is an important cause of morbidity and mortality in severely immunodeficient patients. However, in an immunocompetent patient it represents a diagnostic challenge, mainly because it is extremely rare, but also because of its nonspecific clinical manifestation. Neurovascular involvement in cryptococcal meningitis is rare and not well known and only few reports have described this association. We describe a cryptococcal meningitis in an immunocompetent patient associated with central nervous system vasculitis.<\/jats:p>","DOI":"10.3390\/diseases6030075","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T10:57:52Z","timestamp":1535713072000},"page":"75","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Central Nervous System Vasculitis for Cryptococcosis in an Immunocompetent Patient"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8964-4328","authenticated-orcid":false,"given":"Dan","family":"Zimelewicz Oberman","sequence":"first","affiliation":[{"name":"University Institute, Hospital Italiano de Buenos Aires, Potos\u00ed 1199, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliana","family":"Patrucco","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital Italiano de Buenos Aires, Potos\u00ed 1199, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Cuello Oderiz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Hospital Italiano de Buenos Aires, Potos\u00ed 1199, Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2018,8,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S1473-3099(17)30243-8","article-title":"Global burden of disease of HIV-associated cryptococcal meningitis: An updated analysis","volume":"17","author":"Rajasingham","year":"2017","journal-title":"Lancet Infect Dis."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1046\/j.1524-4733.2002.51108.x","article-title":"The Direct Cost and Incidence of Systemic Fungal Infections","volume":"5","author":"Wilson","year":"2002","journal-title":"Value Health"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/qjmed\/hcl014","article-title":"Cryptococcosis in apparently immunocompetent patients","volume":"99","author":"Lui","year":"2006","journal-title":"QJM"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1385\/IR:35:3:191","article-title":"Immune response and immunotherapy to Cryptococcus infections","volume":"35","author":"Zhou","year":"2006","journal-title":"Immunol Res."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1259\/bjr.74.877.740083","article-title":"Cerebral cryptococcosis: Atypical appearances on CT","volume":"74","author":"Awasthi","year":"2001","journal-title":"Br. 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