{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T20:52:35Z","timestamp":1786481555751,"version":"build-2736575974"},"reference-count":123,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T00:00:00Z","timestamp":1673481600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology which affects the oral mucosa. OLP varies in its clinical features from a reticular form that is, in most cases, asymptomatic, to atrophic\u2013erosive, and is accompanied by symptoms of burning sensation and pain followed by difficulty in eating. Given the fact that OLP is a disease of unknown etiology, the treatment is symptomatic and involves suppressing the signs and symptoms of the disease using various topical and systemic drugs. The first line of therapy for treating symptomatic OLP is topical corticosteroids, whereas systemic corticosteroids are used for treating persistent lesions that do not respond to local treatment. However, the lack of convincing evidence on the efficacy of previous therapies, including topical corticosteroids, and numerous side effects that have appeared over recent years has resulted in the emergence and development of new therapeutic options. Some of the therapies mentioned are tacrolimus, efalizumab, dapson, interferon, retinoic acid, photochemotherapy with psoralen and ultraviolet A rays (PUVA), aloe vera, antimalarials, antibiotics and others. These therapies only partially meet the properties of efficacy and safety of use, thus justifying the continuous search and testing of new treatment methods.<\/jats:p>","DOI":"10.3390\/dj11010026","type":"journal-article","created":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T05:03:03Z","timestamp":1673499783000},"page":"26","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Different Treatment Modalities of Oral Lichen Planus\u2014A Narrative Review"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8369-1024","authenticated-orcid":false,"given":"Ana","family":"Andabak-Rogulj","sequence":"first","affiliation":[{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia"},{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Clinical Hospital Zagreb, 10000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ema","family":"Vindi\u0161","sequence":"additional","affiliation":[{"name":"Dental Practice at Healthcare Center Ormo\u017e, 2270 Ormo\u017e, Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9915-3354","authenticated-orcid":false,"given":"Lorena","family":"Aleksijevi\u0107","sequence":"additional","affiliation":[{"name":"Faculty of Dental Medicine and Health, University of Osijek, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8076-7591","authenticated-orcid":false,"given":"Ivana","family":"\u0160krinjar","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia"},{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Clinical Hospital Zagreb, 10000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7391-6114","authenticated-orcid":false,"given":"Danica","family":"Juras","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia"},{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Clinical Hospital Zagreb, 10000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anastazija","family":"A\u0161\u010di\u0107","sequence":"additional","affiliation":[{"name":"Private Dental Practice, 31000 Osijek, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6096-6796","authenticated-orcid":false,"given":"Bo\u017eana","family":"Brzak","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, 10000 Zagreb, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,1,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4103\/0019-5154.94276","article-title":"Prevalence of oral, skin, and oral and skin lesions of lichen planu sin patients visiting a dental school in southern India","volume":"57","author":"Omal","year":"2012","journal-title":"Indian J. 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