{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:54:32Z","timestamp":1777499672582,"version":"3.51.4"},"reference-count":25,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T00:00:00Z","timestamp":1693267200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"RAK College of Dental Sciences","award":["RAKMHSU-REC-036-2022\/23-UG-D"],"award-info":[{"award-number":["RAKMHSU-REC-036-2022\/23-UG-D"]}]},{"name":"RAK College of Dental Sciences","award":["RAK-REC-REF-12-2023-UG-D"],"award-info":[{"award-number":["RAK-REC-REF-12-2023-UG-D"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Aim: This study aimed to investigate the relationship between dental caries, dental anxiety, and salivary cortisol levels in children visiting pediatric dental clinics and their implications on pediatric oral health. Materials and Methods: A cross-sectional study was conducted at a dental university in the UAE. A total of 60 children, aged 4\u201312 years, were included. Salivary cortisol levels were measured using an Enzyme-Linked Immunosorbent Assay (ELISA) kit. Dental caries status was evaluated, and dental anxiety levels were assessed using the Modified Dental Anxiety Scale (MDAS). Statistical analyses, including Mann-Whitney U test and Pearson\u2019s correlation coefficient, were performed to determine significant differences and associations. Results: The study group showed significantly higher salivary cortisol levels compared to the control group (p &lt; 0.0001). A strong positive correlation was found between salivary cortisol levels and dental caries status (p &lt; 0.001). However, no significant difference in dental anxiety levels was observed between the study and control groups (p = 0.85). A strong positive correlation was found between dental anxiety levels and dental caries status (p &lt; 0.001). Conclusion: The findings indicate a significant association between salivary cortisol levels and dental caries, suggesting that higher cortisol levels are associated with active caries. Dental anxiety levels were positively correlated with dental caries. Understanding the relationship between these variables can contribute to better oral health strategies and interventions for children, emphasizing the importance of managing dental anxiety and stress in pediatric dental care. Clinical Significance: This study highlights the potential of salivary cortisol as a biomarker for assessing stress and its impact on oral health in children. By addressing dental anxiety and stress, dental professionals can provide child-friendly dental care, enhance preventive measures, and improve oral health outcomes in pediatric patients.<\/jats:p>","DOI":"10.3390\/dj11090205","type":"journal-article","created":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T10:47:26Z","timestamp":1693306046000},"page":"205","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Association between Salivary Cortisol Levels, Dental Anxiety, and Dental Caries in Children: A Cross-Sectional Study"],"prefix":"10.3390","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5331-0657","authenticated-orcid":false,"given":"Vivek","family":"Padmanabhan","sequence":"first","affiliation":[{"name":"RAK College of Dental Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0604-9553","authenticated-orcid":false,"given":"Md Sofiqul","family":"Islam","sequence":"additional","affiliation":[{"name":"RAK College of Dental Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muneera","family":"Habib","sequence":"additional","affiliation":[{"name":"RAK College of Dental Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zainab","family":"Abdulaziz","sequence":"additional","affiliation":[{"name":"RAK College of Dental Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manjunatha","family":"Goud","sequence":"additional","affiliation":[{"name":"RAK College of Medical Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nallan CSK","family":"Chaitanya","sequence":"additional","affiliation":[{"name":"RAK College of Dental Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheela","family":"Haridas","sequence":"additional","affiliation":[{"name":"RAK College of Medical Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammed Mustahsen","family":"Rahman","sequence":"additional","affiliation":[{"name":"RAK College of Dental Sciences, RAK Medical and Health Sciences University, Al Juwais, Al Qusaidat, Ras al Khaimah 11172, United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,8,29]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.physbeh.2017.03.021","article-title":"Long-term stability of diurnal salivary cortisol and alphaamylase secretion patterns","volume":"175","author":"Skoluda","year":"2017","journal-title":"Physiol. 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