{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:21:51Z","timestamp":1791645711508,"version":"4.3.4"},"reference-count":35,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Riga Stradins University"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Deproteinised bovine bone (DBB) is widely used as bone substitute in maxillary sinus floor augmentation (MSFA) surgery. No previous studies have shown the long-term volumetric changes in the augmented bone when using DBB. The selected patients had MFSA performed using a lateral window technique and a xenograft, alone or in combination with the patient\u2019s autologous bone from the mandible. Cone beam computed tomography (CBCT) images were used to compare the volumetric changes in the augmented bone for patients over a period of 6 or more years. No significant bone reduction was seen in the augmented bone region when comparing MSFA after 7 months and 6 or more years after dental implantation.<\/jats:p>","DOI":"10.3390\/dj12050121","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T03:56:31Z","timestamp":1713930991000},"page":"121","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Long-Term Volumetric Stability of Maxillary Sinus Floor Augmentation Using a Xenograft Bone Substitute and Its Combination with Autologous Bone: A 6+ Year Retrospective Follow-Up Study Using Cone Beam Computed Tomography"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8875-973X","authenticated-orcid":false,"given":"Liene","family":"Zamure-Damberga","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV-1007 Riga, Latvia"},{"name":"RSU Institute of Stomatology, LV-1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2443-9582","authenticated-orcid":false,"given":"Oskars","family":"Radzins","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV-1007 Riga, Latvia"},{"name":"RSU Institute of Stomatology, LV-1007 Riga, Latvia"},{"name":"Baltic Biomaterials Centre of Excellence, Headquarters at Riga Technical University, LV-1073 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girts","family":"Salms","sequence":"additional","affiliation":[{"name":"RSU Institute of Stomatology, LV-1007 Riga, Latvia"},{"name":"Department of Oral and Maxillofacial Surgery, Riga Stradins University, LV-1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9120-5869","authenticated-orcid":false,"given":"Maksims","family":"Zolovs","sequence":"additional","affiliation":[{"name":"Statistics Unit, Riga Stradins University, LV-1048 Riga, Latvia"},{"name":"Institute of Life Sciences and Technology, Daugavpils University, LV-5401 Daugavpils, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2021-5773","authenticated-orcid":false,"given":"Zanda","family":"Bokvalde","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV-1007 Riga, Latvia"},{"name":"RSU Institute of Stomatology, LV-1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5411-5810","authenticated-orcid":false,"given":"Laura","family":"Neimane","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Oral Health, Riga Stradins University, LV-1007 Riga, Latvia"},{"name":"RSU Institute of Stomatology, LV-1007 Riga, Latvia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/cid.12946","article-title":"Are <7-mm long implants in native bone as effective as longer implants in augmented bone for the rehabilitation of posterior atrophic jaws? A systematic review and meta-analysis","volume":"22","author":"Iezzi","year":"2020","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_2","first-page":"613","article-title":"Grafting of the maxillary sinus floor with autogenous marrow and bone","volume":"38","author":"Boyne","year":"1980","journal-title":"J. Oral Surg."},{"key":"ref_3","first-page":"e1","article-title":"Maxillary Sinus Floor Augmentation with Autogenous Bone Graft Compared with a Composite Grafting Material or Bone Substitute Alone: A Systematic Review and Meta-Analysis Assessing Volumetric Stability of the Grafting Material","volume":"12","author":"Deluiz","year":"2021","journal-title":"J. Oral Maxillofac. Res."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s40729-017-0084-4","article-title":"Autogenous bone grafts in oral implantology-is it still a \u201cgold standard\u201d? A consecutive review of 279 patients with 456 clinical procedures","volume":"3","author":"Sakkas","year":"2017","journal-title":"Int. J. Implant. Dent."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1600-0501.2011.02168.x","article-title":"Maxillary sinus floor augmentation with Bio-Oss or Bio-Oss mixed with autogenous bone as graft: A systematic review","volume":"23","author":"Jensen","year":"2012","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_6","first-page":"e1","article-title":"Maxillary Sinus Floor Augmentation With or Without Barrier Membrane Coverage of the Lateral Window: A Systematic Review and Meta-Analysis","volume":"10","author":"Deluiz","year":"2019","journal-title":"J. Oral Maxillofac. Res."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jpor.2012.12.001","article-title":"Current barrier membranes: Titanium mesh and other membranes for guided bone regeneration in dental applications","volume":"57","author":"Rakhmatia","year":"2013","journal-title":"J. Prosthodont. Res."},{"key":"ref_8","doi-asserted-by":"crossref","unstructured":"Zhang, M., Zhou, Z., Yun, J., Liu, R., Li, J., Chen, Y., Cai, H., Jiang, H.B., Lee, E.S., and Han, J. (2022). Effect of Different Membranes on Vertical Bone Regeneration: A Systematic Review and Network Meta-Analysis. Biomed Res. Int., 2022.","DOI":"10.1155\/2022\/7742687"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1111\/clr.13019","article-title":"Quantitative evaluation of metal artifacts using different CBCT devices, high-density materials and field of views","volume":"28","author":"Codari","year":"2017","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"20140238","DOI":"10.1259\/dmfr.20140238","article-title":"CBCT-based bone quality assessment: Are Hounsfield units applicable?","volume":"44","author":"Pauwels","year":"2015","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"20180021","DOI":"10.1259\/dmfr.20180021","article-title":"Magnitude of cone beam CT image artifacts related to zirconium and titanium implants: Impact on image quality","volume":"47","author":"Fontenele","year":"2018","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects","volume":"310","author":"Association","year":"2013","journal-title":"Jama"},{"key":"ref_13","first-page":"49","article-title":"Maxillary sinus augmentation for endosteal implants: Organized alternative treatment plans","volume":"4","author":"Misch","year":"1987","journal-title":"Int. J. Oral Implantol."},{"key":"ref_14","unstructured":"(2023, December 01). The Jamovi Project (Version 2.3) [Computer Software]. Available online: https:\/\/www.jamovi.org."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"178","DOI":"10.11607\/jomi.3236","article-title":"Three-dimensional volume change of grafted bone in the maxillary sinus","volume":"29","author":"Mazzocco","year":"2014","journal-title":"Int. J. Oral Maxillofac. Implant."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"881","DOI":"10.11607\/jomi.3472","article-title":"Volume changes of maxillary sinus augmentations over time: A systematic review","volume":"29","author":"Shanbhag","year":"2014","journal-title":"Int. J. Oral Maxillofac. Implant."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ijom.2017.05.001","article-title":"A systematic review and meta-analysis of long-term studies (five or more years) assessing maxillary sinus floor augmentation","volume":"47","author":"Aludden","year":"2018","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/jcpe.13055","article-title":"Long-term effectiveness of maxillary sinus floor augmentation: A systematic review and meta-analysis","volume":"46","author":"Raghoebar","year":"2019","journal-title":"J. Clin. Periodontol."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/j.1600-0501.2009.01776.x","article-title":"Clinical outcomes of sinus floor augmentation for implant placement using autogenous bone or bone substitutes: A systematic review","volume":"20","author":"Nkenke","year":"2009","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Pesce, P., Menini, M., Canullo, L., Khijmatgar, S., Modenese, L., Gallifante, G., and Del Fabbro, M. (2021). Radiographic and Histomorphometric Evaluation of Biomaterials Used for Lateral Sinus Augmentation: A Systematic Review on the Effect of Residual Bone Height and Vertical Graft Size on New Bone Formation and Graft Shrinkage. J. Clin. Med., 10.","DOI":"10.3390\/jcm10214996"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1111\/j.1600-0501.2004.00996.x","article-title":"A clinical long-term radiographic evaluation of graft height changes after maxillary sinus floor augmentation with a 2:1 autogenous bone\/xenograft mixture and simultaneous placement of dental implants","volume":"15","author":"Hatano","year":"2004","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Park, W.B., Han, J.Y., and Kang, K.L. (2021). Long-Term Comparison of Survival and Marginal Bone of Implants with and without Sinus Augmentation in Maxillary Molars within the Same Patients: A 5.8- to 22-Year Retrospective Study. J. Clin. Med., 10.","DOI":"10.3390\/jcm10071360"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1111\/clr.12222","article-title":"A 5-year clinical and computerized tomographic implant follow-up in sinus-lifted maxillae and native bone","volume":"25","author":"Sbordone","year":"2014","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1563\/AAID-JOI-D-13-00278","article-title":"A 5-Year Implant Follow-Up in Maxillary and Mandibular Horizontal Osseous Onlay Grafts and Native Bone","volume":"41","author":"Sbordone","year":"2015","journal-title":"J. Oral Implantol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/j.1708-8208.2004.tb00030.x","article-title":"A 5-year prospective follow-up study of implant-supported fixed prostheses in patients subjected to maxillary sinus floor augmentation with an 80:20 mixture of bovine hydroxyapatite and autogenous bone","volume":"6","author":"Hallman","year":"2004","journal-title":"Clin. Implant. Dent. Relat. Res."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1006\/ijom.2003.0512","article-title":"10-year follow-up of onlay bone grafts and implants in severely resorbed maxillae","volume":"33","author":"Ahlqvist","year":"2004","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1054\/ijom.2001.0197","article-title":"Bone graft remodelling and implant success rate in the treatment of the severely resorbed maxilla: A 5-year longitudinal study","volume":"31","author":"Ahlqvist","year":"2002","journal-title":"Int. J. Oral Maxillofac. Surg."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1016\/j.joms.2012.07.040","article-title":"Volume changes of iliac crest autogenous bone grafts after vertical and horizontal alveolar ridge augmentation of atrophic maxillas and mandibles: A 6-year computerized tomographic follow-up","volume":"70","author":"Sbordone","year":"2012","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.jormas.2019.11.004","article-title":"Long-term evaluation of three-dimensional volumetric changes of augmented severely atrophic maxilla by anterior iliac crest bone grafting","volume":"121","author":"Cansiz","year":"2020","journal-title":"J. Stomatol. Oral Maxillofac. Surg."},{"key":"ref_30","first-page":"201","article-title":"BIO-OSS\u2014A resorbable bone substitute?","volume":"8","author":"Schlegel","year":"1998","journal-title":"J. Long Term Eff. Med. Implant."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1902\/jop.2007.070062","article-title":"Anorganic bone matrix retrieved 14 years after a sinus augmentation procedure: A histologic and histomorphometric evaluation","volume":"78","author":"Iezzi","year":"2007","journal-title":"J. Periodontol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1902\/jop.2009.090263","article-title":"A clinical study of 406 sinus augmentations with 100% anorganic bovine bone","volume":"80","author":"Ferreira","year":"2009","journal-title":"J. Periodontol."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Imai, H., Prati, C., Zamparini, F., Iezzi, G., Botticelli, D., Gandolfi, M.G., and Baba, S. (2023). ESEM-EDX Mineralization and Morphological Analysis of Human Retrieved Maxillary Sinus Bone Graft Biopsies before Loading. J. Funct. Biomater., 14.","DOI":"10.3390\/jfb14070391"},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"20210092","DOI":"10.1259\/dmfr.20210092","article-title":"CBCT image artefacts generated by implants located inside the field of view or in the exomass","volume":"51","author":"Koenig","year":"2022","journal-title":"Dentomaxillofac. Radiol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"20140197","DOI":"10.1259\/dmfr.20140197","article-title":"Effective dose of dental CBCT-a meta analysis of published data and additional data for nine CBCT units","volume":"44","author":"Ludlow","year":"2015","journal-title":"Dentomaxillofac. Radiol."}],"container-title":["Dentistry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-6767\/12\/5\/121\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T14:32:59Z","timestamp":1760106779000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-6767\/12\/5\/121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":35,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,5]]}},"alternative-id":["dj12050121"],"URL":"https:\/\/doi.org\/10.3390\/dj12050121","relation":{},"ISSN":["2304-6767"],"issn-type":[{"value":"2304-6767","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]}}}