{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T13:59:00Z","timestamp":1762783140942,"version":"build-2065373602"},"reference-count":26,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universitas Indonesia Research Grant (Q2 International Indexed Publication)","award":["NKB-609\/UN2.RSt\/HKP.05.00\/2022"],"award-info":[{"award-number":["NKB-609\/UN2.RSt\/HKP.05.00\/2022"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Introduction: Chronic oral mucosal diseases (COMDs) can significantly impair the quality of life (QoL) of affected individuals. Monitoring the overall disease\u2019s impact and the efficacy of treatments requires the use of the Chronic Oral Mucosal Diseases Questionnaire-15 (COMDQ-15) as a standardized instrument for measuring QoL in these patients. Objective: This study aimed to assess QoL in patients with COMDs using an Indonesian version of the COMDQ-15. Methods: Seventy patients diagnosed with recurrent aphthous stomatitis (RAS), oral lichen planus, autoimmune blistering diseases (ABD), and cheilitis were included. Levels of QoL among different groups of disease were compared. Various potential factors influencing QoL were evaluated. Bivariate analysis was performed to identify factors associated with overall and specific aspects of QoL. Results: The mean total COMDQ-15 score was 20.83 \u00b1 10.07. The highest scores were in the physical discomfort domain (8.76 \u00b1 4.65), while the lowest was in the medication and treatment domain (2.13 \u00b1 1.99). Physical discomfort was significantly associated with gender, major RAS, and cheilitis. Social and emotional aspects were significantly associated with age and ABD, while patient support was linked to employment status, RAS types, and cheilitis. Conclusions: The Indonesian version of the COMDQ-15 is a valid and reliable tool for assessing QoL in patients with COMDs.<\/jats:p>","DOI":"10.3390\/dj12080258","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T03:46:36Z","timestamp":1723607196000},"page":"258","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of Quality of Life in Patients with Chronic Oral Mucosal Diseases Using the Indonesian Version of the Chronic Oral Mucosal Disease Questionnaire-15 (COMDQ-15)"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9918-1571","authenticated-orcid":false,"given":"Febrina","family":"Rahmayanti","sequence":"first","affiliation":[{"name":"Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6817-1410","authenticated-orcid":false,"given":"Ratna K.","family":"Indrastiti","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0217-291X","authenticated-orcid":false,"given":"Yuniardini S.","family":"Wimardhani","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherlyana","family":"Jozerizal","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dovian Emely","family":"Suteja","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rani","family":"Handayani","sequence":"additional","affiliation":[{"name":"Oral Medicine Specialist, Tangerang City Regional Public Hospital, Tangerang City 15117, Indonesia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paswach","family":"Wiriyakijja","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.det.2020.05.006","article-title":"Chronic Oral Lesions","volume":"38","author":"Bukhari","year":"2020","journal-title":"Dermatol. Clin."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"e123","DOI":"10.7812\/TPP\/13-095","article-title":"Assessment of Quality of Life in Patients with Chronic Oral Mucosal Diseases: A Questionnaire-Based Study","volume":"18","author":"Rajan","year":"2014","journal-title":"Perm. J."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Song, J.S., Hyun, H.K., Shin, T.J., and Kim, Y.J. (2018). Effects of Dental Treatment and Systemic Disease on Oral Health-Related Quality of Life in Korean Pediatric Patients. BMC Oral Health, 18.","DOI":"10.1186\/s12903-018-0552-0"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"29","DOI":"10.5005\/jp-journals-10029-1064","article-title":"Evaluation of Life Quality in Patients with Oral Mucosal Lesions","volume":"3","author":"Baharvand","year":"2014","journal-title":"Int. J. Exp. Dent. Sci."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"687","DOI":"10.17219\/dmp\/142871","article-title":"Dental Implants for Patients with Oral Mucosal Diseases: A Narrative Review and Clinical Guidance","volume":"60","author":"Lamfoon","year":"2023","journal-title":"Dent. Med. Probl."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/s41415-024-7080-x","article-title":"Oral Mucosal Disease: Dilemmas and Challenges in General Dental Practice","volume":"236","author":"Atkin","year":"2024","journal-title":"Br. Dent. J."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"e0092","DOI":"10.1590\/pboci.2021.018","article-title":"Quality of Life in Patients with Chronic Oral Mucosal Conditions: A Qualitative Research","volume":"21","author":"Nassab","year":"2021","journal-title":"Pesqui. Bras. Odontopediatria Cl\u00edn. Integr."},{"key":"ref_8","first-page":"e178","article-title":"Impact of Oral Mucosa Lesions on the Quality of Life Related to Oral Health. An Etiopathogenic Study","volume":"21","author":"Garcia","year":"2016","journal-title":"Med. Oral Patol. Oral Cir. Bucal"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/jop.12964","article-title":"Development and Validation of a Short Version of Chronic Oral Mucosal Disease Questionnaire (COMDQ-15)","volume":"49","author":"Wiriyakijja","year":"2020","journal-title":"J. Oral Pathol. Med."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1601-0825.2011.01844.x","article-title":"Further Reliability and Responsiveness of the Chronic Oral Mucosal Diseases Questionnaire: Quality of Life Questionnaire Testing","volume":"18","author":"Mccreary","year":"2012","journal-title":"Oral Dis."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/idj.12607","article-title":"Health-Related Quality of Life and Its Associated Predictors in Patients with Oral Lichen Planus: A Cross-Sectional Study","volume":"71","author":"Wiriyakijja","year":"2021","journal-title":"Int. Dent. J."},{"key":"ref_12","first-page":"127","article-title":"Validity and Reliability of the Persian Version of the Chronic Oral Mucosal Diseases Questionnaire","volume":"9","author":"Shirzad","year":"2018","journal-title":"Casp. J. Intern. Med."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"573","DOI":"10.17219\/dmp\/146195","article-title":"Oral Heatlh-Related Quality of Life (Ohrqol) in Polish Adults with Periodontal Diseases, Oral Mucosal Diseases and Dental Caries","volume":"59","author":"Wasacz","year":"2022","journal-title":"Dent. Med. Probl."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"100004","DOI":"10.1016\/j.xjidi.2021.100004","article-title":"Epidemiology of Pemphigus","volume":"20","author":"Kridin","year":"2021","journal-title":"JID Innov."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1001\/jamadermatol.2019.3797","article-title":"Global Prevalence and Incidence Estimates of Oral Lichen Planus","volume":"156","author":"Li","year":"2020","journal-title":"JAMA Dermatol."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"893","DOI":"10.5005\/jp-journals-10024-2630","article-title":"Prevalence of Recurrent Aphthous Stomatitis among Dental Students: A Cross Sectional Study","volume":"20","year":"2019","journal-title":"J. Contemp. Dent. Pract."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Radwan-Oczko, M., Sok\u00f3\u0142, I., Babu\u015bka, K., and Owczarek-Drabi\u0144ska, J.E. (2022). Prevalence and Characteristic of Oral Mucosa Lesions. Symmetry, 14.","DOI":"10.3390\/sym14020307"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e832","DOI":"10.1002\/hsr2.832","article-title":"A Clinical and Demographic Analysis of Oral Pemphigus Vulgaris: A Retrospective Cross-Sectional Study from 2001 To 2021","volume":"5","author":"Alshami","year":"2022","journal-title":"Health Sci. Rep."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.clindermatol.2011.03.016","article-title":"Quality of Life in Patients with Bullous Dermatoses","volume":"30","author":"Sebaratnam","year":"2012","journal-title":"Clin. Dermatol."},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"De Abreu, M.H.N.G., Cruz, A.J.S., Borges-Oliveira, A.C., Martins, R.D.C., and Mattos, F.D.F. (2021). Perspectives on Social and Environmental Determinants of Oral Health. Int. J. Environ. Res. Public Health, 20.","DOI":"10.3390\/ijerph182413429"},{"key":"ref_21","first-page":"e2023043","article-title":"Does Pemphigus Vulgaris Affect Oral Health Related Quality of Life?","volume":"22","author":"Salehi","year":"2023","journal-title":"Nat. Life Sci. Commun."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1590\/abd1806-4841.20186228","article-title":"Recurrent Aphthous Ulceration: An Epidemiological Study of Etiological Factors, Treatment and Differential Diagnosis","volume":"93","author":"Siml","year":"2018","journal-title":"An. Bras. Dermatol."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"217","DOI":"10.2147\/CCIDE.S369481","article-title":"Recurrent Aphthous Stomatitis Affects Quality of Life. A Case-Control Study","volume":"14","author":"Rivera","year":"2022","journal-title":"Clin. Cosm. Investig. Dent."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"e2021099","DOI":"10.5826\/dpc.1104a99","article-title":"Recurrent Aphthous Stomatitis: Treatment and Management","volume":"28","author":"Manfredini","year":"2021","journal-title":"Dermatol. Pract. Concept."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"55","DOI":"10.4103\/1735-3327.351344","article-title":"Oral Health-Related Quality of Life in Erosive\/Ulcerative Oral Lichen Planus Patients","volume":"19","author":"Saberi","year":"2022","journal-title":"Dent. Res. J."},{"key":"ref_26","first-page":"342","article-title":"Differential Diagnosis of Cheilitis\u2014How to Classify Cheilitis?","volume":"57","year":"2018","journal-title":"Acta Clin. Croat."}],"container-title":["Dentistry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-6767\/12\/8\/258\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T15:36:19Z","timestamp":1760110579000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-6767\/12\/8\/258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,14]]},"references-count":26,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2024,8]]}},"alternative-id":["dj12080258"],"URL":"https:\/\/doi.org\/10.3390\/dj12080258","relation":{},"ISSN":["2304-6767"],"issn-type":[{"type":"electronic","value":"2304-6767"}],"subject":[],"published":{"date-parts":[[2024,8,14]]}}}