{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:37:06Z","timestamp":1760146626297,"version":"build-2065373602"},"reference-count":24,"publisher":"MDPI AG","issue":"12","license":[{"start":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T00:00:00Z","timestamp":1732492800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Italian Ministry of Health\u2014Current research IRCCS"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background: Dental implants are commonly employed to address edentulism, while orthodontic treatments often incorporate mini-screws to enhance tooth movement and provide stable anchorage. Both procedures are integral to modern dental practice and frequently interact in comprehensive care scenarios. While oral health professionals routinely assess patients\u2019 medical histories before procedures, undiagnosed coagulopathies, such as Von Willebrand Disease (VWD), can present significant challenges when invasive procedures are carried out, such as the insertion of implants or mini-implants. Case description: This case report discusses the surgical placement of dental implants and orthodontic mini-screws in a patient with previously undiagnosed VWD, underscoring the potential complications and the importance of recognizing bleeding disorders in clinical practice, and provides some advice on the management of patients with previously undiagnosed VWD after\/during surgical procedures. Conclusions: To prevent the risk of excessive bleeding, before surgery, all patients should be screened through precise questions on bleeding history.<\/jats:p>","DOI":"10.3390\/dj12120381","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T06:25:19Z","timestamp":1732515919000},"page":"381","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dental Implants and Orthodontic Mini-Screws in a Patient with Undiagnosed Von Willebrand\u2019s Disease: A Case Report"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6476-1357","authenticated-orcid":false,"given":"Alessandro","family":"Bruni","sequence":"first","affiliation":[{"name":"Surgical, Medical and Dental Department, University of Modena and Reggio Emilia, 41121 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4138-0607","authenticated-orcid":false,"given":"Francesca Giulia","family":"Serra","sequence":"additional","affiliation":[{"name":"Private Practice, 10019 Strambino, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3170-521X","authenticated-orcid":false,"given":"Andrea","family":"Abate","sequence":"additional","affiliation":[{"name":"Department of Sciences Integrated Surgical and Diagnostic, University of Genova, 16126 Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2062-6014","authenticated-orcid":false,"given":"Alessandro","family":"Ugolini","sequence":"additional","affiliation":[{"name":"Department of Sciences Integrated Surgical and Diagnostic, University of Genova, 16126 Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5930-1698","authenticated-orcid":false,"given":"Cinzia","family":"Maspero","sequence":"additional","affiliation":[{"name":"Fondazione IRCCS C\u00e0 Granda, Ospedale Maggiore Policlinico, 20122 Milan, Italy"},{"name":"Department of Biomedical Surgical and Dental Sciences, University of Milan, 20122 Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2899-8450","authenticated-orcid":false,"given":"Francesca","family":"Silvestrini Biavati","sequence":"additional","affiliation":[{"name":"Department of Sciences Integrated Surgical and Diagnostic, University of Genova, 16126 Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2191-8673","authenticated-orcid":false,"given":"Valentina","family":"Lanteri","sequence":"additional","affiliation":[{"name":"Surgical, Medical and Dental Department, University of Modena and Reggio Emilia, 41121 Modena, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,25]]},"reference":[{"key":"ref_1","first-page":"3735","article-title":"von Willebrand disease: Advances in pathogenetic understanding, diagnosis, and therapy","volume":"122","author":"Lillicrap","year":"2013","journal-title":"Blood J. 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Haemost."}],"container-title":["Dentistry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-6767\/12\/12\/381\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T16:38:57Z","timestamp":1760114337000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-6767\/12\/12\/381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,25]]},"references-count":24,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["dj12120381"],"URL":"https:\/\/doi.org\/10.3390\/dj12120381","relation":{},"ISSN":["2304-6767"],"issn-type":[{"type":"electronic","value":"2304-6767"}],"subject":[],"published":{"date-parts":[[2024,11,25]]}}}