{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:39:04Z","timestamp":1787027944368,"version":"build-2736575974"},"reference-count":37,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T00:00:00Z","timestamp":1736121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de Nivel Superior-(CAPES-Brazil)-PDPG-POSDOC\/scholarship-CAPES","award":["88887.755620\/2022-00"],"award-info":[{"award-number":["88887.755620\/2022-00"]}]},{"name":"Alexander-von-Humboldt-Foundation (ECK)","award":["88887.755620\/2022-00"],"award-info":[{"award-number":["88887.755620\/2022-00"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background\/Objectives: Dental agenesis is the congenital absence of at least one tooth and has been associated with several other developmental dental conditions, such as morphological dental alterations and Carabelli trait. This study sought to investigate whether third molar agenesis is associated with Carabelli traits in permanent molars. Methods: This was a cross-sectional study that used a convenience sample obtained from the orthodontic records of German patients. Patients with syndromes, oral clefts, congenital alterations including dental agenesis (except agenesis of third molars), and severe cases of bruxism with a loss of tooth tissue were excluded. Teeth with cavitated lesions of dental caries, occlusal wear, restorations, and evident dental deformities were not included in the evaluation. The Carabelli trait was evaluated in the permanent maxillary molars. The Carabelli trait was classified according to its expression for each tooth as either absent, negative, and positive expressions. Third molar agenesis was evaluated only in patients older than 10 years old (based on when initial tooth formation should be visible in the panoramic radiographs). The two-sided Chi-squared test was used to investigate the association between the conditions, using an alpha of 5% (p &lt; 0.05). Results: A total of 155 patients (74 females and 81 males) were investigated; 39 had third molar agenesis and 75 had the Carabelli trait. There was no statistical significance difference between patients with third molar agenesis and those with Carabelli traits in relation to sex (p &gt; 0.05). The Carabelli trait was more common in first molars than in second molars. There was no statistical significant association between third molar agenesis and Carabelli traits (p &gt; 0.05). Conclusions: Third molar agenesis was not associated with the Carabelli trait in the permanent molars in this population.<\/jats:p>","DOI":"10.3390\/dj13010023","type":"journal-article","created":{"date-parts":[[2025,1,6]],"date-time":"2025-01-06T06:43:04Z","timestamp":1736145784000},"page":"23","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Exploring the Association Between Third Molar Agenesis and Carabelli Traits: A Cross-Sectional Study"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4486-1318","authenticated-orcid":false,"given":"Isabela Ribeiro","family":"Madalena","sequence":"first","affiliation":[{"name":"Department of Biomaterials, University of Uberaba, Uberaba 38010-200, Brazil"},{"name":"School of Dentistry, Presidente Tancredo de Almeida Neves University Center, S\u00e3o Jo\u00e3o del Rei 36307-251, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0397-597X","authenticated-orcid":false,"given":"Heloisa Guimar\u00e3es","family":"Resende","sequence":"additional","affiliation":[{"name":"Department of Biomaterials, University of Uberaba, Uberaba 38010-200, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariane Beatriz","family":"Blancato","sequence":"additional","affiliation":[{"name":"Department of Biomaterials, University of Uberaba, Uberaba 38010-200, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Ang\u00e9lica Hueb","family":"de Menezes-Oliveira","sequence":"additional","affiliation":[{"name":"Department of Biomaterials, University of Uberaba, Uberaba 38010-200, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5649-7234","authenticated-orcid":false,"given":"Flares","family":"Baratto-Filho","sequence":"additional","affiliation":[{"name":"School of Dentistry, University of Tuiuti of Paran\u00e1, Curitiba 82010-330, Brazil"},{"name":"School of Dentistry, University of the Joinville Region, Joinville 89219-710, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poliana Ferreira","family":"Santos","sequence":"additional","affiliation":[{"name":"School of Dentistry, Presidente Tancredo de Almeida Neves University Center, S\u00e3o Jo\u00e3o del Rei 36307-251, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila Paiva","family":"Perin","sequence":"additional","affiliation":[{"name":"School of Dentistry, University of the Joinville Region, Joinville 89219-710, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2624-3445","authenticated-orcid":false,"given":"Thais Vilalba Paniagua Machado","family":"do Nascimento","sequence":"additional","affiliation":[{"name":"School of Dentistry, University of the Joinville Region, Joinville 89219-710, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Proff","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University of Regensburg, 93053 Regensburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Kirschneck","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University Hospital Bonn, Medical Faculty, University of Bonn, 53111 Bonn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9sar Penazzo","family":"Lepri","sequence":"additional","affiliation":[{"name":"Department of Biomaterials, University of Uberaba, Uberaba 38010-200, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5351-2526","authenticated-orcid":false,"given":"Erika Calvano","family":"K\u00fcchler","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, University Hospital Bonn, Medical Faculty, University of Bonn, 53111 Bonn, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,6]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Al-Ani, A.H., Antoun, J.S., Thomson, W.M., Merriman, T.R., and Farella, M. 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