{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T11:13:25Z","timestamp":1759922005760,"version":"build-2065373602"},"reference-count":54,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T00:00:00Z","timestamp":1736899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Objectives: This research is purposed to synthesize the existing evidence on implant survival rates in patients with oral potentially malignant disorders (OPMD) and assess potential risk factors associated with peri-implant disease. Material and Methods: A comprehensive search was performed across PubMed MEDLINE, Cochrane Library, and Web of Science. This review was conducted according to the PRISMA guidelines, including studies published between 2012 and 2023. Results: The review of studies related to oral lichen planus (OLP) revealed an implant survival rate of 99.3% (50% to 100%) with a mean follow-up of 40.1 months. One retrospective study focused on patients with leukoplakia and erythroplakia, but did not provide data on implant survival; however, it reported the presence of oral squamous cell carcinomas (OSCC) in the vicinity of dental implants. Data from a patient with proliferative verrucous leukoplakia (PVL) indicated a 100% implant survival rate, while patients with systemic lupus erythematosus (SLE) showed an implant survival rate of 97.67%. For all other entities of OPMD no articles could be found. Conclusions: With the exception of OLP, there is a limited number of studies or none on all other entities of OPMD. The available literature indicates no impact of OLP on implant survival rates and does not support OLP as a risk factor for peri-implant disease. For the other entities of OPMD, no conclusion regarding implant survival or peri-implant disease risk factors can be drawn due to a lack of studies. To validate the results and evaluate OPMD on peri-implant tissue, large-scale prospective studies for all types of OPMD, especially for leukoplakia and erythroplakia, are needed.<\/jats:p>","DOI":"10.3390\/dj13010035","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T09:01:02Z","timestamp":1736931662000},"page":"35","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of Oral Potentially Malignant Disorders (OPMD) on Dental Implants Survival\u2014A Systematic Review"],"prefix":"10.3390","volume":"13","author":[{"given":"Sebahat","family":"Kaya","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Walter","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"},{"name":"Oral and Maxillofacial Surgery of the Mediplus Clinic, Haifa-Allee 20, 55128 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5324-9932","authenticated-orcid":false,"given":"Aya","family":"Khamis","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"},{"name":"Department of Otorhinolaryngology Head and Neck Surgery, Molecular and Cellular Oncology, University Medical Center, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany"},{"name":"Oral Pathology Department, Faculty of Dentistry, Alexandria University, Alexandria 5372066, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8259-3959","authenticated-orcid":false,"given":"Lena Katharina","family":"M\u00fcller-Heupt","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Operative Dentistry, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3784-2063","authenticated-orcid":false,"given":"Stefanie","family":"Zimmer","sequence":"additional","affiliation":[{"name":"Institute of Pathology, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4839-6457","authenticated-orcid":false,"given":"Lorena","family":"Cascant Ortolano","sequence":"additional","affiliation":[{"name":"Departmental Library, University Medical Center Mainz, Johannes Gutenberg-University, 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keyvan","family":"Sagheb","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8665-5803","authenticated-orcid":false,"given":"Bilal","family":"Al-Nawas","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eik","family":"Schiegnitz","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Center, Johannes Gutenberg-University, 55131 Mainz, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,1,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/s12105-019-01020-6","article-title":"Oral Epithelial Dysplasia and Premalignancy","volume":"13","author":"Woo","year":"2019","journal-title":"Head Neck Pathol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1111\/odi.13704","article-title":"Oral potentially malignant disorders: A consensus report from an international seminar on nomenclature and classification, convened by the WHO Collaborating Centre for Oral Cancer","volume":"27","author":"Warnakulasuriya","year":"2021","journal-title":"Oral Dis."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/hed.26006","article-title":"Potentially malignant disorders of the oral cavity and oral dysplasia: A systematic review and meta-analysis of malignant transformation 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