{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:53:34Z","timestamp":1785880414003,"version":"3.56.0"},"reference-count":24,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T00:00:00Z","timestamp":1745625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordination for the Improvement of Higher Education Personnel, Brazil","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination for the Improvement of Higher Education Personnel, Brazil","doi-asserted-by":"publisher","award":["2018\/07060-2"],"award-info":[{"award-number":["2018\/07060-2"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"publisher","award":["2018\/07060-2"],"award-info":[{"award-number":["2018\/07060-2"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background\/Objectives: This study evaluated the effects of vascular photobiomodulation (VPBM) on pain intensity, edema, and facial temperature variation in patients undergoing alveolar bone grafting (ABG) surgery. Methods: A total of 42 patients with cleft lip and palate (aged 9\u201325 years) scheduled for ABG using iliac crest bone were randomly assigned in equal numbers (14 per group) to one of three groups: control (ABG only), test (ABG + VPBM), and placebo (ABG + simulated VPBM). Iliac and facial pain and edema were clinically evaluated 24 h post-surgery, along with thermographic facial analysis. Follow-up was conducted via phone calls for one week. Results: No statistically significant differences were observed among the groups regarding facial pain and edema at 24 h post-surgery. However, iliac pain significantly differed between the placebo and control groups (p = 0.045). A significant time-related effect on both facial and iliac pain outcomes was noted during follow-up, irrespective of the group. The need for rescue medication and self-perception of reduced edema did not differ significantly. Thermographic analysis reveals a significantly lower temperature variation in the test group (2.36 \u00b0C) compared to the other groups (p = 0.007). Conclusions: Overall, VPBM therapy influenced postoperative pain in the early recovery phase and temperature in the immediate postoperative period but did not significantly affect edema.<\/jats:p>","DOI":"10.3390\/dj13050190","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T05:21:31Z","timestamp":1745817691000},"page":"190","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Vascular Photobiomodulation in the Postoperative Period of Alveolar Bone Grafting"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5494-1189","authenticated-orcid":false,"given":"Nicole","family":"de Freitas","sequence":"first","affiliation":[{"name":"Postgraduate Program, Hospital for Rehabilitation of Craniofacial Anomalies, University of S\u00e3o Paulo, S\u00e3o Paulo 17012-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Guerrini","sequence":"additional","affiliation":[{"name":"Independent Researcher, S\u00e3o Paulo 13416-345, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7053-0881","authenticated-orcid":false,"given":"Denise","family":"Haddad","sequence":"additional","affiliation":[{"name":"APCD Sector of Dentistry, S\u00e3o Paulo 02011-000, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Sector of Oral and Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of Sao Paulo, S\u00e3o Paulo 17012-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Yaed\u00fa","sequence":"additional","affiliation":[{"name":"Sector of Oral and Maxillofacial Surgery, Hospital for Rehabilitation of Craniofacial Anomalies, University of Sao Paulo, S\u00e3o Paulo 17012-901, Brazil"},{"name":"Department of Surgery, Stomatology, Pathology and Radiology, Bauru School of Dentistry, University of S\u00e3o Paulo, S\u00e3o Paulo 17012-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2288-9624","authenticated-orcid":false,"given":"Ana","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Periodontics, Bauru School of Dentistry, University of S\u00e3o Paulo, S\u00e3o Paulo 17012-901, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/S1678-77572012000100003","article-title":"Rehabilitative treatment of cleft lip and palate: Experience of the Hospital for Rehabilitation of Craniofacial Anomalies\/USP (HRAC\/USP)-Part 1: Overall aspects","volume":"20","author":"Freitas","year":"2012","journal-title":"J. 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