{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:12:57Z","timestamp":1760058777447,"version":"build-2065373602"},"reference-count":29,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Objectives: The fluoride-releasing properties of restorative materials are crucial for the prevention of secondary caries as these can act as fluoride reservoirs. Hence, the present study aimed to investigate, assess, and compare the impact of time, temperature, and storage conditions on the fluoride release of silorane-based composites (SBCs) and methacrylate-based composites (MBCs), and also evaluate the variation in their reuptake of fluoride (after recharge). Methods: SBC and MBC test samples of 10 mm \u00d7 2 mm dimensions were prepared and tested for fluoride release and recharge in distilled water and artificial saliva at temperatures of 4 \u00b0C, 37 \u00b0C, and 55 \u00b0C. The amount of fluoride released (at 1, 7, 14, and 28 days) and re-released after recharge (with 5000 ppm neutral sodium fluoride (NaF) solution for 5 min at 1, 3, and 7 days for 3 weeks) were studied with the help of a fluoride-selective ion electrode. Results: SBCs had a greater release of fluoride at low temperature in artificial saliva (0.07 \u00b1 0.03) when compared to MBCs (0.04 \u00b1 0.005). Fluoride release increased on day 7 but decreased over time (p &lt; 0.05). Fluoride re-release was greater in MBCs than SBCs and it increased with time (p &lt; 0.05). Conclusion: The amount of fluoride release and recharge depends on the time interval, temperature, and storage condition. These restorative materials can serve as fluoride reservoirs and contribute to sustained fluoride release in oral fluids, thereby preventing the initiation of secondary caries and the failure of restorations. In addition, it may assist in developing measures to improve fluoride delivery for topical applications.<\/jats:p>","DOI":"10.3390\/dj13050197","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T05:05:57Z","timestamp":1745989557000},"page":"197","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Influence of Time Interval, Temperature, and Storage Condition on Fluoride Release and Recharge from Silorane-Based Restorative Materials"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7281-3153","authenticated-orcid":false,"given":"Prashanthi S.","family":"Madhyastha","sequence":"first","affiliation":[{"name":"Department of Dental Materials, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal 575001, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilip G.","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Periodontics, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal 575001, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2686-0397","authenticated-orcid":false,"given":"Srikant","family":"Natarajan","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal 575001, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel Sarah","family":"Vinodhini","sequence":"additional","affiliation":[{"name":"Department of Dental Materials, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal 575001, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,4,30]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0109-5641(01)00071-9","article-title":"In vitro biocompatibility of oxirane\/polyol dental composites with promising physical properties","volume":"18","author":"Eick","year":"2002","journal-title":"Dent. 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