{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T13:51:38Z","timestamp":1792504298598,"version":"4.5.0"},"reference-count":30,"publisher":"MDPI AG","issue":"8","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Introduction: Dental caries remains a public health concern, and early detection prevents its progression and complications. Panoramic radiographs are essential diagnostic tools, yet the interpretation of panoramic X-rays varies among practitioners. Artificial intelligence (AI) presents a promising approach to enhance diagnostic accuracy in detecting dental caries. This scoping review examines the current literature on the use of AI programs to analyze panoramic radiographs for the diagnosis of dental caries. Methods: This scoping review searched PubMed, Scopus, Web of Science, and Dentistry and Oral Sciences Source, adhering to PRISMA guidelines. The review included peer-reviewed, original research published in English that investigated the use of AI to diagnose dental caries. Data were extracted on the AI model characteristics, advantages, disadvantages, and diagnostic performance. Results: Seven studies met the inclusion criteria. The Deep Learning Model achieved the highest performance (specificity 0.9487, accuracy 0.9789, F1 score 0.9245), followed by Diagnocat and Tooth Type Enhanced Transformer. Models such as CranioCatch and CariSeg showed moderate performance, while the Dental Caries Detection Network demonstrated the lowest. Benefits included improved diagnostic support and workflow efficiency, while limitations involved dataset biases, interpretability challenges, and computational demands. Conclusions: Applying AI technologies to panoramic X-rays demonstrates the potential for enhancing caries diagnosis, with some models achieving near-expert performance. However, future research must address the generalizability, transparency, and integration of AI models into clinical practice. Future research should focus on diverse training datasets, explainable AI development, clinical validation, and incorporating AI training into dental education and training.<\/jats:p>","DOI":"10.3390\/dj13080366","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T16:30:36Z","timestamp":1755016236000},"page":"366","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Charting New Territory: AI Applications in Dental Caries Detection from Panoramic Imaging"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2827-3740","authenticated-orcid":false,"given":"Man","family":"Hung","sequence":"first","affiliation":[{"name":"College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA"},{"name":"Division of Public Health, University of Utah, Salt Lake City, UT 84108, USA"},{"name":"School of Business, University of Utah, Salt Lake City, UT 84112, USA"},{"name":"Primary Children\u2019s Hospital, Salt Lake City, UT 84113, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Yevseyevich","sequence":"additional","affiliation":[{"name":"College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Khazana","sequence":"additional","affiliation":[{"name":"College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3954-582X","authenticated-orcid":false,"given":"Connor","family":"Schwartz","sequence":"additional","affiliation":[{"name":"College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA"},{"name":"Library, Roseman University of Health Sciences, South Jordan, UT 84095, USA"},{"name":"Library, Noorda College of Osteopathic Medicine, Provo, UT 84606, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1749-8477","authenticated-orcid":false,"given":"Martin S.","family":"Lipsky","sequence":"additional","affiliation":[{"name":"College of Dental Medicine, Roseman University of Health Sciences, South Jordan, UT 84095, USA"},{"name":"Institute on Aging, Portland State University, Portland, OR 97207, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e041","DOI":"10.1590\/1807-3107bor-2022.vol36.0041","article-title":"Impact of dental caries on oral health-related quality of life in children with dental behavior management problems","volume":"36","author":"Silva","year":"2022","journal-title":"Braz. 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