{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:30:54Z","timestamp":1789587054074,"version":"build-2803163510"},"reference-count":33,"publisher":"MDPI AG","issue":"9","license":[{"start":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:00:00Z","timestamp":1756339200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Spanish Instituto de Salud Carlos III, Ministry of Science, Innovation and Universities","doi-asserted-by":"publisher","award":["ICI19\/00024 (BIOCLEFT)"],"award-info":[{"award-number":["ICI19\/00024 (BIOCLEFT)"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Regional Development Fund (FEDER\/ERDF)","award":["ICI19\/00024 (BIOCLEFT)"],"award-info":[{"award-number":["ICI19\/00024 (BIOCLEFT)"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background: Children affected by unilateral cleft lip and palate (UCLP) represent a therapeutic challenge requiring the development of novel therapies, such as the implant of a bioengineered tissue\u2014BIOCLEFT\u2014or the use of nasoalveolar molding (NAM). The objective of this work was to evaluate the effects of NAM on the surgical and aesthetic outcomes of children with UCLP. Methods: A total of 36 children with UCLP treated at a craniofacial malformations management unit were evaluated, including 23 patients treated with presurgical NAM followed by palate surgical correction (NAM group) and 13 patients treated surgically without previous NAM (non-NAM group). Measurements were obtained from each patient immediately before palate surgery, including four linear measurements: nasal ala projection length (NAPL), nasal dome height (NDH), superoinferior alar groove position (S-I AGP), and nasal dome position (M-L NDP), and two angular measurements: columellar deviation (CD) and nasal bridge deviation (NBD). Results: When NAM was used, a significant improvement of the basilar view linear measurements of the patient\u2019s nose was found, including the NAPL and NDH, and the frontal view linear measurement M-L NDP, but not S-I AGP. Significant improvements were also observed in the angular measurements of nasal symmetry CD and NBD. All these variables, except the S-I AGP, significantly correlated with the treatment group, and two variables\u2014NAPL and CD\u2014significantly contributed to generate a predictive model developed using binary logistic regression. Conclusions: These findings support the use of NAM to efficiently improve the nasal symmetry and the presurgical outcomes of patients with UCLP.<\/jats:p>","DOI":"10.3390\/dj13090394","type":"journal-article","created":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T15:03:14Z","timestamp":1756393394000},"page":"394","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating the Effectiveness of Nasoalveolar Molding in the Management of Children with Unilateral Cleft Lip and Palate: A Cohort Study"],"prefix":"10.3390","volume":"13","author":[{"given":"Alba","family":"Espa\u00f1a-Guerrero","sequence":"first","affiliation":[{"name":"Doctoral Program in Clinical Medicine and Public Health, University of Granada, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Espa\u00f1a-Guerrero","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, University of Granada, 18071 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Liceras-Liceras","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, University Hospital Virgen de las Nieves, 18014 Granada, Spain"},{"name":"Craniofacial Malformations and Cleft Lip and Palate Management Unit (Unidad de Fisurados Labiopalatinos y Malformaciones Craneofaciales), University Hospital Virgen de las Nieves, 18014 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Bullejos-Mart\u00ednez","sequence":"additional","affiliation":[{"name":"University Hospital Foundation Jim\u00e9nez D\u00edaz, 28040 Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adoraci\u00f3n","family":"Mart\u00ednez-Plaza","sequence":"additional","affiliation":[{"name":"Craniofacial Malformations and Cleft Lip and Palate Management Unit (Unidad de Fisurados Labiopalatinos y Malformaciones Craneofaciales), University Hospital Virgen de las Nieves, 18014 Granada, Spain"},{"name":"Division of Oral y Maxillofacial Surgery, University Hospital Virgen de las Nieves, 18014 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4876-2672","authenticated-orcid":false,"given":"Miguel","family":"Alaminos","sequence":"additional","affiliation":[{"name":"Tissue Engineering Group, Department of Histology, School of Medicine, University of Granada, 18016 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria ibs.GRANADA, 18012 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Fern\u00e1ndez-Valad\u00e9s","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery, University Hospital Virgen de las Nieves, 18014 Granada, Spain"},{"name":"Craniofacial Malformations and Cleft Lip and Palate Management Unit (Unidad de Fisurados Labiopalatinos y Malformaciones Craneofaciales), University Hospital Virgen de las Nieves, 18014 Granada, Spain"},{"name":"Tissue Engineering Group, Department of Histology, School of Medicine, University of Granada, 18016 Granada, Spain"},{"name":"Instituto de Investigaci\u00f3n Biosanitaria ibs.GRANADA, 18012 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Espa\u00f1a-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, University of Granada, 18071 Granada, Spain"},{"name":"Craniofacial Malformations and Cleft Lip and Palate Management Unit (Unidad de Fisurados Labiopalatinos y Malformaciones Craneofaciales), University Hospital Virgen de las Nieves, 18014 Granada, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,8,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"120","DOI":"10.2340\/jphs.v60.43739","article-title":"Birth Prevalence of Cleft Lip and\/or Palate\u2014A Register Study of All Children Born in Sweden Years 2000\u20132020","volume":"60","author":"Cornefjord","year":"2025","journal-title":"J. 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