{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:58:25Z","timestamp":1770746305498,"version":"3.49.0"},"reference-count":20,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background: The majority of cleft palate patients have been reported to suffer from otitis media with effusion (OME). The improvement of velopharyngeal function (VPF) after palatoplasty might be evidence for the improvement of the function of the Eustachian tube. The improvement of the function of Eustachian tube by palatoplasty has been reported to be effective for the treatment of OME simultaneously with the insertion of a ventilation tube into the tympanic membrane. There are only a few reports that clearly show the association between improvement of VPF and improvement of OME after palatoplasty. In this study, we discussed whether the improvement of VPF after palatoplasty in cleft palate patients with OME improved OME. Methods: Twenty-six patients with cleft palate were included in the study. We retrospectively extracted the information of cleft type, gender, surgical technique, and presence of OME risk factors from electronic medical records. We also investigated the recurrence of OME and the improvement level of VPF at 36 months postoperatively. OME was assessed based on the otolaryngologist\u2019s findings in electronic medical records, with a good prognosis group with no symptom of OME, or a recurrence group with prolonged or recurrent OME. Results: At 36 months after palatoplasty, 19 of 23 patients (82.6%) were in the OME good prognosis group and four (17.4%) were in the OME recurrence group. The rate of patients with recurrent OME did not differ significantly by the degree of improvement of VPF. This study indicated that clear association between other risk factors for OME and OME recurrence could not be shown. Conclusion: We observed that most patients with cleft palate who underwent palatoplasty showed a good prognosis for OME at 36 months after surgery. However, further studies are needed to investigate the impact of different surgical techniques on the improvement of OME and the degree to which VPF improves, as well as the effect of each OME risk factor.<\/jats:p>","DOI":"10.3390\/dj14020086","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T16:46:28Z","timestamp":1770137188000},"page":"86","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Does Palatoplasty in Patients with Cleft Palate Really Improve Otitis Media with Effusion?"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2417-4156","authenticated-orcid":false,"given":"Yosuke","family":"Kunitomi","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"},{"name":"Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiki","family":"Hyodo","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"},{"name":"Section of Dentistry, Oral and Maxillofacial Surgery, Sano Kosei General Hospital, Tochigi 327-8511, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiaki","family":"Kitsukawa","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"},{"name":"Utsunomiya General Service Corps, Japan Ground Self-Defense Forces, Tochigi 321-0145, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aya","family":"Koike","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Tsubura","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"},{"name":"Yasu Kazu Charm Dental Clinic, Tochigi 320-0846, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2301-6895","authenticated-orcid":false,"given":"Yuske","family":"Komiyama","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5160-6892","authenticated-orcid":false,"given":"Chonji","family":"Fukumoto","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9838-6734","authenticated-orcid":false,"given":"Takahiro","family":"Wakui","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6605-6486","authenticated-orcid":false,"given":"Hiroshi","family":"Kamioka","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8525, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Kawamata","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Dokkyo Medical University School of Medicine, Tochigi 321-0293, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1054\/bjom.2000.0539","article-title":"Incidence of cleft lip or palate in 303738 Japanese babies born between 1994 and 1995","volume":"38","author":"Natsume","year":"2000","journal-title":"Br. J. Oral Maxillofac. Surg."},{"key":"ref_2","first-page":"e2023924","article-title":"Long Term Study of Otitis Media with Effusion after Palatoplasty and Myringotomy with Ventilation Tube Insertion","volume":"41","author":"Peerasak","year":"2023","journal-title":"J. Health Sci. Med. Res."},{"key":"ref_3","first-page":"7","article-title":"Middle ear complications in clefts. Results of stage I. in long term studies of hearing defects, considering type of cleft and age of patient","volume":"15","year":"1973","journal-title":"Acta Chir. Plast."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"111071","DOI":"10.1016\/j.ijporl.2022.111071","article-title":"Prognosis of Otitis Media with Effusion in Pediatric Patients with Cleft Palate During Language-acquisition Period Treated by Simultaneous Tympanostomy Tube Placement with Palatoplasty","volume":"155","author":"Okano","year":"2022","journal-title":"Int. J. Pediatr. Otorhinolaryngol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1002\/lio2.933","article-title":"Relationship between cleft palate width and otitis media","volume":"7","author":"Yoshitomi","year":"2022","journal-title":"Laryngoscope Investig. Otolaryngol."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"405.e1","DOI":"10.1016\/j.joms.2018.09.027","article-title":"Effect of Cleft Palate Closure Technique on Speech and Middle Ear Outcome: A Systematic Review","volume":"77","author":"Ruymaekers","year":"2019","journal-title":"J. Oral Maxillofac. Surg."},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3109\/02813438909103668","article-title":"Environmental Risk Factors for Otitis Media with Effusion in Preschool Children","volume":"7","author":"Gerhard","year":"1989","journal-title":"Scand. J. Prim. Health Care"},{"key":"ref_8","first-page":"325","article-title":"Prevalence and risk factors of Otitis Media with effusion in school children in Qassim Region of Saudi Arabia","volume":"8","author":"Khan","year":"2014","journal-title":"Int. J. Health Sci."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.aller.2016.03.004","article-title":"Allergic rhinitis and allergy are risk factors for otitis media with effusion: A meta-analysis","volume":"45","author":"Cheng","year":"2017","journal-title":"Allergol. Immunopathol."},{"key":"ref_10","first-page":"209","article-title":"Correlation between Allergic Rhinitis and Otitis Media with Effusion","volume":"31","author":"Mohammad","year":"2019","journal-title":"Iran. J. Otorhinolaryngol."},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"133","DOI":"10.14639\/0392-100X-2456","article-title":"Risk factors for otitis media with effusion in childrenwith adenoid hypertrophy","volume":"40","author":"Murat","year":"2020","journal-title":"Acta Otorhinolaryngol. Ital."},{"key":"ref_12","first-page":"298","article-title":"Biinku heisakino kensaho nitsuite [Epipharynx closure functional inspection]","volume":"26","author":"Ohira","year":"1993","journal-title":"Jpn. J. Voice Speech Disord."},{"key":"ref_13","first-page":"230","article-title":"Iinkai hokokuKogairetsu gengo kensa (Gengo rinsho yo) [Committee reports: Assessment of cleft palate speech (for clinical speech therapy)]","volume":"26","author":"Miura","year":"2009","journal-title":"Jpn. J. Commun. Disord."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.anl.2023.06.005","article-title":"A manual of Eustachian tube function tests-illustration of representative test results obtained from healthy subjects and typical disorders with suggestion of the appropriate test method of choice","volume":"51","author":"Ikeda","year":"2024","journal-title":"Auris Nasus Larynx"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"e444","DOI":"10.1097\/SCS.0000000000002751","article-title":"Cleft palate repair using adouble opposing Z-plasty","volume":"27","author":"Craig","year":"2016","journal-title":"J. Craniofacial Surg."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/ijos.2014.59","article-title":"The impact of cleft lip and palate repair on maxillofacial growth","volume":"7","author":"Bing","year":"2015","journal-title":"Int. J. Oral Sci."},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"46","DOI":"10.20517\/2347-9264.2020.97","article-title":"Effects of various surgical protocols on maxillofacial growth in patients with unilateral cleft lip and palate: A systematic review","volume":"7","author":"Corthouts","year":"2020","journal-title":"Plast. Aesthetic Res."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0377-1237(06)80010-9","article-title":"Furlow\u2019s Palatoplasty for Cleft Palate Repair","volume":"62","author":"Ravishanker","year":"2006","journal-title":"Med. J. Armed Forces India"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"184","DOI":"10.4295\/audiology.60.184","article-title":"Change over the years in the incidence rate of otitis media with effusion in children with a cleft palate","volume":"60","author":"Maekawa","year":"2017","journal-title":"Audiol. Jpn."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.anl.2022.12.004","article-title":"Clinical practice guidelines for the diagnosis and management of otitis media with effusion (OME) in children in Japan\u20142022 update","volume":"50","author":"Hidaka","year":"2023","journal-title":"Auris Nasus Larynx"}],"container-title":["Dentistry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-6767\/14\/2\/86\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T05:12:45Z","timestamp":1770700365000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-6767\/14\/2\/86"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,3]]},"references-count":20,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026,2]]}},"alternative-id":["dj14020086"],"URL":"https:\/\/doi.org\/10.3390\/dj14020086","relation":{},"ISSN":["2304-6767"],"issn-type":[{"value":"2304-6767","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,3]]}}}