{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:20:26Z","timestamp":1790961626152,"version":"4.1.0"},"reference-count":61,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background\/Objective: Advanced peri-implantitis presents a significant challenge in contemporary implant dentistry and sometimes necessitates implant removal when regenerative therapies are no longer reliable. Protocols for staged bone reconstruction, re-implantation, and definitive prosthetic rehabilitation following peri-implantitis continue to evolve. This study aims to present a clinical case of advanced peri-implantitis with vertical interproximal bone loss managed with a staged surgical and prosthetic approach and review current concepts in implant removal, bone regeneration, re-implantation, and soft-tissue management. Methods: A patient with peri-implantitis affecting two maxillary implants underwent treatment over one year. The initial surgical stage included removal of the failing implants and reconstruction of the defects using guided bone regeneration with a composite graft of 50% xenogeneic bone substitute and 50% autogenous bone, covered by a barrier membrane. After six months of healing, a second surgical stage was performed, involving placement of two new implants in positions 2.2 and 2.4, additional bone augmentation, and soft tissue grafting to enhance soft tissue volume and the width of keratinized gingiva following mucogingival line rebounce. After an additional six months of osseointegration, full maxillary prosthetic rehabilitation was completed in August 2025. Results: Clinical and radiographic assessments demonstrated successful bone regeneration, stable implant integration, adequate peri-implant soft-tissue conditions, and favorable functional and esthetic outcomes at follow-up. The case is discussed in the context of current evidence regarding indications for implant removal, regenerative strategies after explantation, timing of re-implantation, and the importance of keratinized gingiva and prosthetic design in long-term peri-implant health. Conclusions: Staged explantation, guided bone regeneration, delayed re-implantation, and comprehensive soft-tissue and prosthetic management may represent a viable treatment strategy in selected cases of advanced peri-implantitis.<\/jats:p>","DOI":"10.3390\/dj14040212","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T08:09:00Z","timestamp":1775549340000},"page":"212","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Management of Advanced Peri-Implantitis with Staged Explantation and Delayed Re-Implantation in the Esthetic Zone"],"prefix":"10.3390","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4834-9662","authenticated-orcid":false,"given":"Alexandru","family":"Sp\u00eenu","sequence":"first","affiliation":[{"name":"Doctoral School, Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania"},{"name":"Spinu Dental Clinic, Spinu Learning, 410155 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2153-1148","authenticated-orcid":false,"given":"Felicia","family":"Manole","sequence":"additional","affiliation":[{"name":"Surgical Disciplines Department, Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7869-7595","authenticated-orcid":false,"given":"Alexandru","family":"Burcea","sequence":"additional","affiliation":[{"name":"Department of Speciality Disciplines, \u201cTitu Maiorescu\u201d University, 031593 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9783-149X","authenticated-orcid":false,"given":"Cristina-Crengu\u0163a","family":"Albu","sequence":"additional","affiliation":[{"name":"Department of Genetics, Faculty of Dentistry, \u201cCarol Davila\u201d University of Medicine and Pharmacy, 020021 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Argint","sequence":"additional","affiliation":[{"name":"Spinu Dental Clinic, Spinu Learning, 410155 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lavinia-Florica","family":"M\u0103rcu\u021b","sequence":"additional","affiliation":[{"name":"Surgical Disciplines Department, Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roxana Daniela","family":"Brata","sequence":"additional","affiliation":[{"name":"Medical Disciplines Department, Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3410-3870","authenticated-orcid":false,"given":"Alexia","family":"Manole","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Pharmacy, University of Oradea, 410068 Oradea, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5965-893X","authenticated-orcid":false,"given":"Claudia Florina","family":"Bogdan-Andreescu","sequence":"additional","affiliation":[{"name":"Department of Speciality Disciplines, \u201cTitu Maiorescu\u201d University, 031593 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Sartoretto, S.C., Shibli, J.A., Javid, K., Cotrim, K., Canabarro, A., Louro, R.S., Lowenstein, A., Mour\u00e3o, C.F., and Moraschini, V. (2023). Comparing the Long-Term Success Rates of Tooth Preservation and Dental Implants: A Critical Review. J. Funct. Biomater., 14.","DOI":"10.3390\/jfb14030142"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.32542\/implantology.2024013","article-title":"Evaluation of Criteria for Dental Implant Success: A Systematic Literature Review","volume":"28","author":"Lee","year":"2024","journal-title":"J. Implantol. Appl. Sci."},{"key":"ref_3","doi-asserted-by":"crossref","unstructured":"Astolfi, V., R\u00edos-Carrasco, B., Gil-Mur, F.J., R\u00edos-Santos, J.V., Bull\u00f3n, B., Herrero-Climent, M., and Bull\u00f3n, P. (2022). Incidence of Peri-Implantitis and Relationship with Different Conditions: A Retrospective Study. Int. J. Environ. Res. Public Health, 19.","DOI":"10.3390\/ijerph19074147"},{"key":"ref_4","doi-asserted-by":"crossref","unstructured":"Diaz, P., Gonzalo, E., Villagra, L.J.G., Miegimolle, B., and Suarez, M.J. (2022). What Is the Prevalence of Peri-Implantitis? A Systematic Review and Meta-Analysis. BMC Oral Health, 22.","DOI":"10.1186\/s12903-022-02493-8"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"105914","DOI":"10.1016\/j.jdent.2025.105914","article-title":"The Prevalence of Peri-Implant Mucositis and Peri-Implantitis Based on the World Workshop Criteria: A Systematic Review and Meta-Analysis","volume":"160","author":"Reis","year":"2025","journal-title":"J. Dent."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Ting, M., and Suzuki, J.B. (2024). Peri-Implantitis. Dent. J., 12.","DOI":"10.3390\/dj12080251"},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Shiba, T., Komatsu, K., Takeuchi, Y., Koyanagi, T., Taniguchi, Y., Takagi, T., Maekawa, S., Nagai, T., Kobayashi, R., and Matsumura, S. (2024). Novel Flowchart Guiding the Non-Surgical and Surgical Management of Peri-Implant Complications: A Narrative Review. Bioengineering, 11.","DOI":"10.3390\/bioengineering11020118"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"27","DOI":"10.21037\/fomm-24-36","article-title":"Surgical regenerative therapy for peri-implantitis\u2014A comprehensive review and what is the current histological evidence?","volume":"7","author":"Chiang","year":"2025","journal-title":"Front. Oral Maxillofac. Med."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Di Palo, M.P. (2025). Peri-Implantitis Treatment on Microbial Decontamination. Microorganisms, 13.","DOI":"10.3390\/microorganisms13071681"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1055\/s-0040-1715779","article-title":"Peri-implantitis Update: Risk Indicators, Diagnosis, and Treatment","volume":"14","author":"Rokaya","year":"2020","journal-title":"Eur. J. Dent."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Froum, S.J. (2022). Treatment of advanced peri-implantitis with regenerative therapy: A review of the rationale, technique, and outcomes. Front. Oral Maxillofac. Med., 4.","DOI":"10.21037\/fomm-21-30"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"295","DOI":"10.5051\/jpis.2303360168","article-title":"Comprehensive treatment protocol for peri-implantitis: An up-to date narrative review of the literature","volume":"54","author":"Hong","year":"2024","journal-title":"J. Periodontal Implant Sci."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1563\/aaid-joi-D-24-00098","article-title":"Threshold for Implant Removal in Peri-implantitis Defects. Is There Any?","volume":"51","author":"Zimmer","year":"2025","journal-title":"J. Oral Implantol."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.jdsr.2024.01.002","article-title":"Treatment strategies for dental implant removal: A literature review","volume":"60","author":"Masaki","year":"2024","journal-title":"Jpn. Dent. Sci. Rev."},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"670","DOI":"10.11607\/ijp.6718","article-title":"Full arch rehabilitation after failure of implants and teeth supporting an extensive fixed dental prosthesis: A staged approach","volume":"34","author":"Cordaro","year":"2021","journal-title":"Int. J. Prosthodont."},{"key":"ref_16","first-page":"115","article-title":"Implanto-prosthetic rehabilitation in the posterior mandubular region. Case study","volume":"1","author":"Nuca","year":"2023","journal-title":"Rom. J. Oral Rehabil."},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Tallarico, M., Meloni, S.M., Cacci\u00f2, C., Ceruso, F.M., and Lumbau, A.I. (2025). A Second Chance: Managing Late Implant Failure from Peri-Implantitis with Computer-Guided Bone Regeneration\u2014A Clinical Case Report. Reports, 8.","DOI":"10.20944\/preprints202506.0612.v1"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1111\/cid.13209","article-title":"Bone regeneration as treatment of peri-implant disease: A narrative review","volume":"25","author":"Noelken","year":"2023","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1111\/prd.12510","article-title":"Clinical efficacy of guided bone regeneration in peri-implantitis defects. A network meta-analysis","volume":"93","author":"Ramanauskaite","year":"2023","journal-title":"Periodontol. 2000"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"De Pace, R., Molinari, S., Mazzoni, E., and Perale, G. (2025). Bone Regeneration: A Review of Current Treatment Strategies. J. Clin. Med., 14.","DOI":"10.3390\/jcm14061838"},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1111\/jcpe.13823","article-title":"Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline","volume":"50","author":"Herrera","year":"2023","journal-title":"J. Clin. Periodontol."},{"key":"ref_22","doi-asserted-by":"crossref","unstructured":"Jankowski, T., Jankowska, A., Kazimierczak, N., Kazimierczak, W., and Janiszewska-Olszowska, J. (2024). The Significance of Keratinized Mucosa in Implant Therapy: Narrative Literature Review and Case Report Presentation. J. Clin. Med., 13.","DOI":"10.3390\/jcm13123501"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1038\/s41415-024-7050-3","article-title":"A literature review on prosthetically designed guided implant placement and the factors influencing dental implant success","volume":"236","author":"Nulty","year":"2024","journal-title":"Br. Dent. J."},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1038\/s41415-024-7406-8","article-title":"Maintenance of peri-implant health in general dental practice","volume":"236","author":"Perussolo","year":"2024","journal-title":"Br. Dent. J."},{"key":"ref_25","first-page":"e79557","article-title":"Soft Tissue Management in Implant Dentistry: A Comprehensive Review","volume":"17","author":"Agarwal","year":"2025","journal-title":"Cureus"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1002\/JPER.25-0270","article-title":"AO\/AAP consensus on prevention and management of peri-implant diseases and conditions: Summary report","volume":"96","author":"Wang","year":"2025","journal-title":"J. Periodontol."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"S286","DOI":"10.1111\/jcpe.12957","article-title":"Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Berglundh","year":"2018","journal-title":"J. Clin. Periodontol."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/cid.12791","article-title":"Morphology and severity of peri-implantitis bone defects","volume":"21","author":"Monje","year":"2019","journal-title":"Clin. Implant Dent. Relat. Res."},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Albu, \u015e.-D., Suciu, I., Albu, C.-C., Dragomirescu, A.-O., and Ionescu, E. (2024). Impact of Malocclusions on Periodontopathogenic Bacterial Load and Progression of Periodontal Disease: A Quantitative Analysis. Microorganisms, 12.","DOI":"10.3390\/microorganisms12081553"},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Palombo, D., R\u00edos-Barbero, J., Conforti, T., and Chiapasco, M. (2026). Autologous Bone for Periodontal and Craniofacial Regeneration: Donor Sites, Characteristics and Indications. J. Periodontal Res., advance online publication.","DOI":"10.1111\/jre.70065"},{"key":"ref_31","doi-asserted-by":"crossref","unstructured":"Mordini, L., Sun, N., Chang, N., De Guzman, J.-P., Generali, L., and Consolo, U. (2021). Peri-Implantitis Regenerative Therapy: A Review. Biology, 10.","DOI":"10.3390\/biology10080773"},{"key":"ref_32","first-page":"625","article-title":"Peri-implantitis Treatment with a Regenerative Approach: Clinical Outcomes on Reentry","volume":"35","author":"Roncati","year":"2015","journal-title":"Int. J. Periodontics Restor. Dent."},{"key":"ref_33","doi-asserted-by":"crossref","unstructured":"Barbagallo, G., di Gregorio, F., Monaca, G., Al\u00ec, G., and Porto, V. (2024). Regenerative Reconstructive Treatment of A Peri-Implantitis Case: New Perspectives for Implant Surface Decontamination. J. Surg., 9.","DOI":"10.29011\/2575-9760.001984"},{"key":"ref_34","doi-asserted-by":"crossref","unstructured":"Alahmari, A., Costa-Berenguer, X., Figueiredo, R., Valmaseda-Castell\u00f3n, E., S\u00e1nchez-Torres, A., and Garc\u00eda-Garc\u00eda, M. (2025). Reconstructive Therapy in Patients with Peri-Implantitis in a University Dental Hospital: A Preliminary Retrospective Case Series Focusing on Complications. Appl. Sci., 15.","DOI":"10.3390\/app15148040"},{"key":"ref_35","first-page":"439","article-title":"Decision Tree for Reconstructive Treatment of Peri-implantitis Defects","volume":"45","author":"Urban","year":"2025","journal-title":"Int. J. Periodontics Restor. Dent."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1186\/s12967-024-05944-8","article-title":"Role of periodontal ligament fibroblasts in periodontitis: Pathological mechanisms and therapeutic potential","volume":"22","author":"Huang","year":"2024","journal-title":"J. Transl. Med."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/s41368-025-00354-y","article-title":"Exploring the mechanical and biological interplay in the periodontal ligament","volume":"17","author":"Wen","year":"2025","journal-title":"Int. J. Oral Sci."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1111\/jopr.13560","article-title":"Tooth preservation vs. extraction and implant placement in periodontally compromised patients: A systematic review and analysis of studies","volume":"31","author":"Sarafidou","year":"2022","journal-title":"J. Prosthodont."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"101931","DOI":"10.1016\/j.jebdp.2023.101931","article-title":"Long-term outcomes of implant placement versus tooth preservation in periodontally compromised teeth may be comparable","volume":"24","author":"Afrashtehfar","year":"2024","journal-title":"J. Evid. Based Dent. Pract."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/s41415-025-8337-8","article-title":"Endodontic and dental implant treatment: Key considerations and comparisons","volume":"238","author":"Bhuva","year":"2025","journal-title":"Br. Dent. J."},{"key":"ref_41","first-page":"53","article-title":"The Importance of Maxillary Canine: A Review","volume":"4","author":"Salehi","year":"2019","journal-title":"J. Dent."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"94","DOI":"10.32542\/implantology.2022008","article-title":"Complications of Teeth and Implants Adjacent to Canine Implants: A Retrospective Study","volume":"26","author":"Lee","year":"2022","journal-title":"J. Implantol. Appl. Sci."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1902\/jop.1992.63.12.995","article-title":"The effect of the distance from the contact point to the crest of bone on the presence or absence of the interproximal dental papilla","volume":"63","author":"Tarnow","year":"1992","journal-title":"J. Periodontol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1902\/jop.2001.72.10.1364","article-title":"Clinical and radiographic evaluation of the papilla level adjacent to single-tooth dental implants. A retrospective study in the maxillary anterior region","volume":"72","author":"Choquet","year":"2001","journal-title":"J. Periodontol."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/clr.13116","article-title":"Papilla height in relation to the distance between bone crest and interproximal contact point at single-tooth implants: A systematic review","volume":"29","author":"Roccuzzo","year":"2018","journal-title":"Clin. Oral Implant. Res."},{"key":"ref_46","doi-asserted-by":"crossref","unstructured":"Maynalovska, H., and Kotsilkov, K. (2025). Association Between Vertical Bone Defects and Interdental Papilla Loss in Periodontitis: A Cross-Sectional Analysis. Dent. J., 13.","DOI":"10.3390\/dj13070294"},{"key":"ref_47","first-page":"43","article-title":"Optimizing esthetics for implant restorations in the anterior maxilla: Anatomic and surgical considerations","volume":"19","author":"Buser","year":"2004","journal-title":"Int. J. Oral Maxillofac. Implant."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1902\/jop.2004.75.9.1242","article-title":"Effect of the vertical and horizontal distances between adjacent implants and between a tooth and an implant on the incidence of interproximal papilla","volume":"75","author":"Gastaldo","year":"2004","journal-title":"J. Periodontol."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"613","DOI":"10.11607\/prd.2481","article-title":"Vertical Ridge Augmentation and Soft Tissue Reconstruction of the Anterior Atrophic Maxillae: A Case Series","volume":"35","author":"Urban","year":"2015","journal-title":"Int. J. Periodontics Restor. Dent."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1111\/jcpe.13289","article-title":"Periodontal regeneration versus extraction and dental implant or prosthetic replacement of teeth severely compromised by attachment loss to the apex: A randomized controlled clinical trial reporting 10-year outcomes, survival analysis and mean cumulative cost of recurrence","volume":"47","author":"Cortellini","year":"2020","journal-title":"J. Clin. Periodontol."},{"key":"ref_51","doi-asserted-by":"crossref","unstructured":"B\u0103d\u0103r\u0103u-\u0218uster, A.-M., Bechir, E.S., Bardocz-Veres, Z., Laz\u0103r, A.P., Vlasa, A., Suciu, M., Coman, T.-M., and Laz\u0103r, L. (2025). Recent Advances in Regenerative Therapies in Periodontology. Dent. J., 13.","DOI":"10.3390\/dj13120564"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1111\/prd.12418","article-title":"Management and sequelae of dental implant removal","volume":"88","author":"Monje","year":"2022","journal-title":"Periodontol. 2000"},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"32","DOI":"10.37358\/MP.17.1.4779","article-title":"The advantages of high-density polymer CAD\/CAM interim restorations in oral implantology","volume":"54","author":"Andreescu","year":"2017","journal-title":"Mater. Plast."},{"key":"ref_54","first-page":"108","article-title":"Enhanced properties and multifaceted applications of polymethyl methacrylate (PMMA) in modern medicine and dentistry","volume":"16","author":"Burcea","year":"2024","journal-title":"Rom. J. Oral Rehabil."},{"key":"ref_55","first-page":"427","article-title":"Digital PMMA, When and Which","volume":"16","author":"Burcea","year":"2024","journal-title":"Rom. J. Oral Rehabil."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1007\/s00784-023-04892-9","article-title":"The effect of a convergent transmucosal neck on soft tissues and radiographic outcomes: A 1-year follow-up randomized controlled trial","volume":"27","author":"Salido","year":"2023","journal-title":"Clin. Oral Investig."},{"key":"ref_57","doi-asserted-by":"crossref","unstructured":"Zamparini, F., Spinelli, A., Gandolfi, M.G., and Prati, C. (2024). 10 Years of Convergent Neck Implants: A Systematic Review of Clinical Outcomes, Initial Original Concepts, and Changes in Surgical and Prosthetic Protocols. Appl. Sci., 14.","DOI":"10.3390\/app14177568"},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1111\/jcpe.70018","article-title":"Convex Versus Concave Emergence Profile of Implant-Supported Crowns in the Aesthetic Zone: 3-Year Results of a Randomized Controlled Trial","volume":"52","author":"Endres","year":"2025","journal-title":"J. Clin. Periodontol."},{"key":"ref_59","doi-asserted-by":"crossref","unstructured":"Agust\u00edn-Panadero, R., Bustamante-Hern\u00e1ndez, N., Labaig-Rueda, C., Fons-Font, A., Fern\u00e1ndez-Estevan, L., and Sol\u00e1-Ru\u00edz, M.F. (2019). Influence of Biologically Oriented Preparation Technique on Peri-Implant Tissues; Prospective Randomized Clinical Trial with Three-Year Follow-Up. Part II: Soft Tissues. J. Clin. Med., 8.","DOI":"10.3390\/jcm8122223"},{"key":"ref_60","first-page":"e643","article-title":"Volumetric variation of peri-implant soft tissues in convergent collar implants and crowns using the biologically oriented preparation technique (BOPT)","volume":"24","year":"2019","journal-title":"Med. Oral Patol. Oral Y Cir. Bucal"},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s40729-025-00649-z","article-title":"Effect of prosthetic emergence profile on labial transmucosal tissue in anterior implants: A retrospective cohort study","volume":"11","author":"Okamoto","year":"2025","journal-title":"Int. J. Implant Dent."}],"container-title":["Dentistry Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-6767\/14\/4\/212\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T08:51:11Z","timestamp":1775551871000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-6767\/14\/4\/212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,7]]},"references-count":61,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,4]]}},"alternative-id":["dj14040212"],"URL":"https:\/\/doi.org\/10.3390\/dj14040212","relation":{},"ISSN":["2304-6767"],"issn-type":[{"value":"2304-6767","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,7]]}}}