{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:13:34Z","timestamp":1788578014149,"version":"build-2803163510"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T00:00:00Z","timestamp":1776384000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","award":["2014\/50891-1"],"award-info":[{"award-number":["2014\/50891-1"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"award":["2014\/50891-1"],"award-info":[{"award-number":["2014\/50891-1"]}],"id":[{"id":"https:\/\/ror.org\/02ddkpn78","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"CNPQ","doi-asserted-by":"publisher","award":["312586\/2021-3"],"award-info":[{"award-number":["312586\/2021-3"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Institute-Technology-Translational Medicine"},{"name":"INCT Digital Mental Health","award":["409148\/2024-5"],"award-info":[{"award-number":["409148\/2024-5"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background: The relationship between facial aesthetic procedures and changes in the stomatognathic system has attracted increasing interest, motivating investigations into their functional and structural impacts. This longitudinal observational study analyzed molar bite force and orofacial tissue pressure in adults who underwent hyaluronic acid injections in the mandibular angle. Methods: Ten adults (eight women and two men; mean age 34.3 \u00b1 11.2 years) with normal occlusion and no temporomandibular disorders were included. The MD Codes guided injection points of 2 mL of hyaluronic acid in the mandibular angle. Maximum right and left molar bite force was measured using a digital dynamometer, and tongue, lip, and cheek pressures were measured with a Pro-Fono Biofeedback device. Assessments occurred before and at 15, 30, and 60 days. Repeated measures ANOVA with Bonferroni correction was applied (p &lt; 0.05), and effect sizes and 95% confidence intervals were calculated. Results: No statistically significant differences were observed in maximum molar bite force throughout the follow-up period. Regarding orofacial pressures, a significant main effect of time was observed for tongue pressure (p = 0.03); however, the effect size was moderate-to-large, and values showed considerable variability across participants. Lip and cheek pressures remained stable over time. Conclusions: Hyaluronic acid injection in the mandibular angle did not show clinically detectable changes in maximum molar bite force, suggesting short-term preservation of masticatory function within the 60-day follow-up period. These findings are limited to short-term observations and specific sample characteristics. The observed variation in tongue pressure may reflect adaptive functional adjustments, although variability across participants was considerable.<\/jats:p>","DOI":"10.3390\/dj14040241","type":"journal-article","created":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T10:11:04Z","timestamp":1776420664000},"page":"241","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of Orofacial Function After Mandibular Angle Harmonization with Hyaluronic Acid: A Longitudinal Observational Study"],"prefix":"10.3390","volume":"14","author":[{"given":"Nicole Barbosa","family":"Bettiol","sequence":"first","affiliation":[{"name":"Department of Basic and Oral Biology, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, Avenida do Caf\u00e9, No Number, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franciele Aparecida","family":"de Carvalho","sequence":"additional","affiliation":[{"name":"Department of Basic and Oral Biology, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, Avenida do Caf\u00e9, No Number, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9756-3771","authenticated-orcid":false,"given":"Selma","family":"Siessere","sequence":"additional","affiliation":[{"name":"Department of Basic and Oral Biology, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, Avenida do Caf\u00e9, No Number, Ribeir\u00e3o Preto 14040-904, Brazil"},{"name":"National Institute-Technology-Translational Medicine (INCT.TM) and INCT Digital Mental Health, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovana Dornelas Azevedo","family":"Romero","sequence":"additional","affiliation":[{"name":"Department of Basic and Oral Biology, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, Avenida do Caf\u00e9, No Number, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcio","family":"de Menezes","sequence":"additional","affiliation":[{"name":"School of Health Science, State University of Amazonas, Avenida Carvalho Leal, 1777, Manaus 69065-001, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catia Cristina Janjacomo","family":"Martini","sequence":"additional","affiliation":[{"name":"Department of Basic and Oral Biology, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, Avenida do Caf\u00e9, No Number, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9889-1790","authenticated-orcid":false,"given":"Jardel Francisco","family":"Mazzi-Chaves","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, S\u00e3o Paulo, Avenida do Caf\u00e9, s\/n, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8050-4396","authenticated-orcid":false,"given":"La\u00eds Valencise","family":"Magri","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, S\u00e3o Paulo, Avenida do Caf\u00e9, s\/n, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4110-8299","authenticated-orcid":false,"given":"Simone Cecilio Hallak","family":"Regalo","sequence":"additional","affiliation":[{"name":"Department of Basic and Oral Biology, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, Avenida do Caf\u00e9, No Number, Ribeir\u00e3o Preto 14040-904, Brazil"},{"name":"National Institute-Technology-Translational Medicine (INCT.TM) and INCT Digital Mental Health, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3445-8154","authenticated-orcid":false,"given":"Marcelo","family":"Palinkas","sequence":"additional","affiliation":[{"name":"Department of Basic and Oral Biology, Ribeir\u00e3o Preto School of Dentistry, University of S\u00e3o Paulo, Avenida do Caf\u00e9, No Number, Ribeir\u00e3o Preto 14040-904, Brazil"},{"name":"National Institute-Technology-Translational Medicine (INCT.TM) and INCT Digital Mental Health, Ribeir\u00e3o Preto 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e5382","DOI":"10.1097\/GOX.0000000000005382","article-title":"Facial beauty and the correlation of associated 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