{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T16:00:09Z","timestamp":1785427209251,"version":"3.56.0"},"reference-count":30,"publisher":"MDPI AG","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad Norbert Wiener, Lima, Peru"},{"id":[{"id":"https:\/\/ror.org\/04abrpb32","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background\/Objectives: Denture stomatitis is closely associated with Candida albicans colonization of denture-base surfaces. This in vitro study compared early adhesion (1 h) and initial biofilm formation (24 h) of C. albicans across five denture-base-related material groups using adhered cell counts and adhered\/inoculum proportions. Methods: A 5 \u00d7 2 factorial design (five material groups; 1 and 24 h) evaluated a comparator pattern resin, heat-polymerized acrylic resin, autopolymerizing acrylic resin, milled CAD\/CAM PMMA, and microwave-polymerized acrylic resin. All specimens underwent standardized finishing and mechanical polishing before microbiological testing. Data were log10-transformed and analyzed by two-way ANOVA (material group, time) with Tukey\u2019s post hoc test. An external SEM-based qualitative laboratory report was used as complementary documentation of C. albicans presence after 1 h and 24 h; representative micrographs and quantitative SEM image outputs were unavailable. Results: Material group, time, and their interaction significantly affected adhered C. albicans counts (p &lt; 0.05). At 1 h, the comparator pattern resin showed the highest adhesion, whereas at 24 h, milled CAD\/CAM PMMA showed the highest adhered load. For the adhered\/inoculum fraction, both material group and time were significant; at 24 h, the heat-polymerized acrylic resin showed the lowest adhered fraction. Conclusions: Under the standardized finishing and mechanical polishing conditions of this in vitro model, the tested material groups showed different C. albicans adhesion\/biofilm patterns over time; clinical extrapolation should be made with caution.<\/jats:p>","DOI":"10.3390\/dj14050262","type":"journal-article","created":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:33:17Z","timestamp":1777627997000},"page":"262","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of Denture Base Fabrication on Candida albicans Adhesion and Early Biofilm: An In Vitro Comparison of Five Techniques"],"prefix":"10.3390","volume":"14","author":[{"given":"Victor","family":"Moreno-Prieto","sequence":"first","affiliation":[{"name":"Facultad de Ciencias de la Salud, Escuela de Odontolog\u00eda, Universidad Norbert Wiener, Av. Arequipa 444, Lima 15046, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Enrique","family":"Guill\u00e9n-Galarza","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Escuela de Odontolog\u00eda, Universidad Norbert Wiener, Av. Arequipa 444, Lima 15046, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian Esteban","family":"G\u00f3mez-Carri\u00f3n","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Escuela de Odontolog\u00eda, Universidad Norbert Wiener, Av. Arequipa 444, Lima 15046, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Schwan-Silva","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias de la Salud, Escuela de Odontolog\u00eda, Universidad Norbert Wiener, Av. Arequipa 444, Lima 15046, Peru"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,5,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Peri\u0107, M., Mili\u010di\u0107, B., Kuzmanovi\u0107 Pfi\u0107er, J., \u017divkovi\u0107, R., and Arsi\u0107 Arsenijevi\u0107, V. (2024). A Systematic Review of Denture Stomatitis: Predisposing Factors, Clinical Features, Etiology, and Global Candida spp.. Distrib. J. Fungi, 10.","DOI":"10.3390\/jof10050328"},{"key":"ref_2","doi-asserted-by":"crossref","unstructured":"Alqarawi, F.K., and Gad, M.M. (2024). Tendency of Microbial Adhesion to Denture Base Resins: A Systematic Review. Front. 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