{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T02:01:57Z","timestamp":1781056917989,"version":"3.54.1"},"reference-count":19,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background\/Objectives: Although gingivitis is the most common oral disease in children, periodontitis accompanied by alveolar bone resorption may develop in patients with severe congenital neutropenia. However, no reports to date have focused on changes in the alveolar bone of these patients during long-term follow-up. Case Summary: A girl aged 8 years and 5 months who developed leukemia due to severe neutropenia was admitted to the hospital and referred to the pediatric dentistry department for oral care. Panoramic radiographs at the first visit revealed significant alveolar bone resorption and mobility in the remaining deciduous teeth. We provided oral care, and the patient later underwent a hematopoietic stem cell transplant. No oral mucositis was observed. Measurement of alveolar bone thickness in the anterior and posterior regions revealed that the ratio increased as the patient\u2019s systemic condition improved, showing a relative increase in alveolar bone thickness in the posterior region. Conclusions: Although this report is descriptive and observational, the patient\u2019s alveolar bone loss with severe congenital neutropenia improved as the patient\u2019s systemic condition improved. In addition, improvement of alveolar bone loss was observed along with systemic recovery and tooth eruption.<\/jats:p>","DOI":"10.3390\/dj14060355","type":"journal-article","created":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:58:12Z","timestamp":1781053092000},"page":"355","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Improvement of Alveolar Bone in a Child with Severe Congenital Neutropenia: Long-Term Clinical Outcomes"],"prefix":"10.3390","volume":"14","author":[{"given":"Tatsuya","family":"Akitomo","sequence":"first","affiliation":[{"name":"Department of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Kusaka","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Hiroshima University Hospital, Hiroshima 734-8551, Japan"},{"name":"Department of Pediatric Dentistry, School of Dentistry, Osaka Dental University, Osaka 573-1121, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimei","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Hiroshima University Hospital, Hiroshima 734-8551, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryota","family":"Nomura","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"ref_1","first-page":"165","article-title":"Periodontal Disease and Dental Caries among children and Adolescents Suffering from Endocrine Disorders\u2014A Literature Review","volume":"15","author":"Saminsky","year":"2017","journal-title":"Pediatr. 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