{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T14:32:26Z","timestamp":1775831546149,"version":"3.50.1"},"reference-count":45,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T00:00:00Z","timestamp":1544400000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background: This study aimed to characterize and test the antimicrobial susceptibility of Lactococcus lactis isolated in endodontic infections in Burkina Faso. Material and methods: This was a prospective study conducted at the Municipal Oral Health Center of Ouagadougou, Burkina Faso, from June to October 2014. Clinical data were collected using a questionnaire form. The method of streaking on selective medium was used to isolate bacteria. Identification was made using the API 20 Strep gallery. Antibiotic susceptibility was performed by the diffusion method on solid medium. Results: One hundred and twenty-five (125) patients were received with a significant proportion from the age group of 19 to 40 years (55.2%). Apical periodontitis accounted for 50.4% and cellulitis for 49.6% of cases. Lactococcus lactis ssp. lactis was identified in five exudate samples. Isolates were 100% resistant to cefixime and metronidazole, 80% to ceftriaxone, cefuroxime, cefotaxime, chloramphenicol and 60% to penicillin G, amoxicillin, amoxicillin clavulanic acid. A multidrug resistance of more than three families of antibiotics was noticed. No strains produced extended spectrum \u00df-lactamases. Conclusion: Lactococcus lactis is part of endodontic biofilm. The reported strong antibiotic resistance involving endodontic therapy will focus on the effect of the disinfectant solution and the mechanical action of the canal instruments.<\/jats:p>","DOI":"10.3390\/dj6040069","type":"journal-article","created":{"date-parts":[[2018,12,10]],"date-time":"2018-12-10T03:36:41Z","timestamp":1544413001000},"page":"69","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Characterization and Antimicrobial Susceptibility of Lactococcus lactis Isolated from Endodontic Infections in Ouagadougou, Burkina Faso"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4220-9534","authenticated-orcid":false,"given":"Wendpoulomd\u00e9 Aim\u00e9 D\u00e9sir\u00e9","family":"Kabor\u00e9","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food (LaBESTA)\/Center for Research in Biological, Food and Nutritional Sciences (CRSBAN)\/Graduate School of Science and Technology (EDST), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"},{"name":"Training and Research Unit in Health Sciences (UFR\/SDS), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9","family":"Demb\u00e9l\u00e9","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food (LaBESTA)\/Center for Research in Biological, Food and Nutritional Sciences (CRSBAN)\/Graduate School of Science and Technology (EDST), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Touwendsida Serge","family":"Bagr\u00e9","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food (LaBESTA)\/Center for Research in Biological, Food and Nutritional Sciences (CRSBAN)\/Graduate School of Science and Technology (EDST), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2134-4609","authenticated-orcid":false,"given":"Ali","family":"Konat\u00e9","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food (LaBESTA)\/Center for Research in Biological, Food and Nutritional Sciences (CRSBAN)\/Graduate School of Science and Technology (EDST), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Boisram\u00e9","sequence":"additional","affiliation":[{"name":"University Laboratory of Biodiversity and Microbial Ecology, EA 3882\/University of Western Brittany, 22 av C. Desmoulins 29238 Brest CEDEX, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9rie","family":"Chevalier","sequence":"additional","affiliation":[{"name":"Department of Odontology Conservative and Endodontics, University of Western Brittany, 22 av C. Desmoulins 29238 Brest CEDEX, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarcissus","family":"Konsem","sequence":"additional","affiliation":[{"name":"Training and Research Unit in Health Sciences (UFR\/SDS), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred S.","family":"Traor\u00e9","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food (LaBESTA)\/Center for Research in Biological, Food and Nutritional Sciences (CRSBAN)\/Graduate School of Science and Technology (EDST), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Barro","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Biology, Epidemiology and Surveillance of Bacteria and Viruses Transmitted by Food (LaBESTA)\/Center for Research in Biological, Food and Nutritional Sciences (CRSBAN)\/Graduate School of Science and Technology (EDST), University of Ouaga I, Professor Joseph KI-ZERBO, Ouagadougou 03 BP 7021, Burkina Faso"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2018,12,10]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/s12903-018-0520-8","article-title":"Apical periodontitis: Preliminary assessment of microbiota by 16S rRNA high throughput amplicon target sequencing","volume":"18","author":"Mussano","year":"2018","journal-title":"BMC Oral Health"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.cden.2016.11.004","article-title":"Odontogenic Infections","volume":"61","author":"Ogle","year":"2018","journal-title":"Dent. 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