{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T02:49:03Z","timestamp":1788922143026,"version":"build-2803163510"},"reference-count":12,"publisher":"MDPI AG","issue":"2","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Introduction: Osteonecrosis of the jaw is defined as exposed bone in the oral cavity that does not heal longer than eight weeks after identification. The two most common predisposing factors for osteonecrosis of the jaw are medication-related and radiotherapy. Rarely, exposed bone in the maxillofacial region can occur due to other causes and represents a clinical and therapeutic challenge for the dentist because there is no universally accepted treatment protocol. Case presentation: We report a case of a patient with two idiopathic lesions of exposed bone which have healed after systemic antibiotic therapy, seven weeks after the first examination. Conclusion: Exposed bone lesions of the jaw are a rare entity and are poorly documented in the literature. It is necessary to exclude possible local or systemic contributing factors. Surgical and conservative therapy (antibiotics) are the treatment of choice.<\/jats:p>","DOI":"10.3390\/dj7020055","type":"journal-article","created":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T02:08:40Z","timestamp":1559527720000},"page":"55","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Idiopathic Exposed Bone Lesions of the Jaw"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6096-6796","authenticated-orcid":false,"given":"Bo\u017eana","family":"Lon\u010dar Brzak","sequence":"first","affiliation":[{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb 10 000, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanja","family":"Vu\u010di\u010devi\u0107 Boras","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb 10 000, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Kotarac Kne\u017eevi\u0107","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb 10 0000, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mato","family":"Su\u0161i\u0107","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb 10 0000, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Seiwerth","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine, University of Zagreb, Clinical Hospital Centre Zagreb, Zagreb 10 000, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dragana","family":"Gabri\u0107","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, School of Dental Medicine, University of Zagreb, Zagreb 10 0000, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,6,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1359\/jbmr.0707onj","article-title":"American Society for Bone and Mineral Research. 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Surg."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1053\/sarh.2002.33724b","article-title":"Pathogenesis and Natural History of Osteonecrosis","volume":"32","author":"Chang","year":"2002","journal-title":"Semin. Arthritis Rheum."},{"key":"ref_5","first-page":"157","article-title":"Coagulopathies in the Pathogenesis of Osteonecrosis","volume":"11","author":"Jones","year":"1997","journal-title":"Orthop. Trauma"},{"key":"ref_6","unstructured":"Jarman, M.I., Lee, K., Kanevsky, A., Min, S., Schlam, I., Mahida, C., Huda, A., Milgrom, A., Goldenberg, N., and Glueck, C.J. (2017). Case Report: Primary Osteonecrosis Associated with Thrombophilia-Hypofibrinolysis and Worsened by Testosterone Therapy. 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