{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T02:23:16Z","timestamp":1789525396642,"version":"build-2803163510"},"reference-count":53,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T00:00:00Z","timestamp":1603238400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"University of Rijeka","award":["uniri-biomed-18-65"],"award-info":[{"award-number":["uniri-biomed-18-65"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Candida-associated denture stomatitis (CADS) is a fungal infection affecting 60\u201365% of denture wearers. Its etiology is complex and multifactorial and often associated with host immunodeficiency. Evidence exists that vitamin D has potential immunomodulatory and anti-inflammatory effects. The aim of this case\u2013control study was to assess the association between vitamin D levels and CADS. The study included 32 complete denture wearers with CADS and 32 sex- and age-matched complete denture wearers without CADS. The patients were clinically examined, and the severity of denture stomatitis was assessed according to Newton\u2019s classification scale. The serum vitamin D level was determined via the use of an electrochemiluminescence assay. The vitamin D level in the CADS group and control group was 54.68 \u00b1 17.07 and 56.82 \u00b1 17.75 nmol\/L, respectively. There was no significant difference between the groups (p = 0.622). Univariate logistic regression analysis showed that the presence of CADS was not associated with hypovitaminosis D (odds ratio (OR) = 1.44; 95% confidence interval (CI) = 0.37\u20135.54). It can be concluded that vitamin D is not associated with CADS and does not play a significant role in host susceptibility to CADS. This finding suggests that vitamin D screening is not indicated routinely in patients with Candida-associated denture stomatitis.<\/jats:p>","DOI":"10.3390\/dj8040121","type":"journal-article","created":{"date-parts":[[2020,10,22]],"date-time":"2020-10-22T10:27:58Z","timestamp":1603362478000},"page":"121","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Association between Vitamin D and Candida-Associated Denture Stomatitis"],"prefix":"10.3390","volume":"8","author":[{"given":"Miranda","family":"Muhvi\u0107-Urek","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Periodontology, Faculty of Dental Medicine, University of Rijeka, Kresimirova 40, 51 000 Rijeka, Croatia"},{"name":"Dental Clinic, Clinical Hospital Center Rijeka, Kresimirova 40, 51 000 Rijeka, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ema","family":"Saltovi\u0107","sequence":"additional","affiliation":[{"name":"Dental Clinic, Clinical Hospital Center Rijeka, Kresimirova 40, 51 000 Rijeka, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alen","family":"Braut","sequence":"additional","affiliation":[{"name":"Dental Clinic, Clinical Hospital Center Rijeka, Kresimirova 40, 51 000 Rijeka, Croatia"},{"name":"Department of Restorative Dentistry and Endodontics, Faculty of Dental Medicine, University of Rijeka, Kresimirova 40, 51 000 Rijeka, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Kova\u010devi\u0107 Pavi\u010di\u0107","sequence":"additional","affiliation":[{"name":"Dental Clinic, Clinical Hospital Center Rijeka, Kresimirova 40, 51 000 Rijeka, Croatia"},{"name":"Department of Prosthodontics, Faculty of Dental Medicine, University of Rijeka, Kresimirova 40, 51 000 Rijeka, Croatia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2020,10,21]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1834-7819.1998.tb00152.x","article-title":"Candida-associated denture stomatitis. 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