{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T12:46:34Z","timestamp":1787921194175,"version":"build-2784847793"},"reference-count":66,"publisher":"MDPI AG","issue":"6","license":[{"start":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T00:00:00Z","timestamp":1622678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dentistry Journal"],"abstract":"<jats:p>Background: Due to the lack of data comparing the biological behavior of two formulations, granules and paste, of alloplastic graft from microtomographic and histomorphometric points of view, the aim of the present experiment was to compare the histomorphometric and microtomographic healing of two formulations, i.e., granules (MR sites) or paste (MR-inject sites) of an alloplastic graft composed of a combination of beta-tricalcium phosphate and hydroxyapatite used for maxillary sinus lifting. Methods: A sinus lifting procedure was carried out bilaterally in 20 rabbits, and the elevated space was filled with either paste or granules of an alloplastic material. A collagen membrane was placed on the antrostomy and the animals were euthanized after 2 or 10 weeks, 10 animals each group. Microtomographic and histological analyses were performed. Results: Higher proportions of new bone formation were found at the MR, compared to the MR-inject sites both after 2 weeks (2.65 \u00b1 2.89% vs. 0.08 \u00b1 0.12%; p &lt; 0.01) and 10 weeks of healing (34.20 \u00b1 13.86 vs. 23.28 \u00b1 10.35%; p = 0.022). Conclusions: It was concluded that new bone formation was faster in the MR sites, compared to the MR-inject. However, a longer time of healing should be allowed to make final conclusions about the efficiency in bone formation of the paste formulation of the biomaterial used in the present study.<\/jats:p>","DOI":"10.3390\/dj9060065","type":"journal-article","created":{"date-parts":[[2021,6,3]],"date-time":"2021-06-03T10:59:51Z","timestamp":1622717991000},"page":"65","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Maxillary Sinus Augmentation Using Ceramic Alloplastic Granules or Paste: An Experimental Study in Rabbits"],"prefix":"10.3390","volume":"9","author":[{"given":"Michael Medeiros","family":"Costa","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Periodontology, Faculty of Dentistry of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, S\u00e3o Paulo 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2804-1632","authenticated-orcid":false,"given":"Daniele","family":"Botticelli","sequence":"additional","affiliation":[{"name":"ARDEC Academy, 47923 Rimini, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofer","family":"Moses","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Dental Implantology, School of Dental Medicine, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Omori","sequence":"additional","affiliation":[{"name":"ARDEC Academy, 47923 Rimini, Italy"},{"name":"Department of Oral Implantology, Osaka Dental University, Osaka 573-1144, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeo","family":"Fujiwara","sequence":"additional","affiliation":[{"name":"ARDEC Academy, 47923 Rimini, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erick Ricardo","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Periodontology, Faculty of Dentistry of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, S\u00e3o Paulo 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7389-5886","authenticated-orcid":false,"given":"Samuel Porfirio","family":"Xavier","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery and Periodontology, Faculty of Dentistry of Ribeir\u00e3o Preto, University of S\u00e3o Paulo, S\u00e3o Paulo 14040-904, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,6,3]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"773","DOI":"10.11607\/prd.1288","article-title":"Long-term implant survival in the grafted maxillary sinus: A systematic review","volume":"33","author":"Wallace","year":"2013","journal-title":"Int. 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