{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T03:34:11Z","timestamp":1760240051181,"version":"build-2065373602"},"reference-count":25,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Entropy"],"abstract":"<jats:p>Hypsarrhythmia is an electroencephalographic pattern specific to some epileptic syndromes that affect children under one year of age. The identification of this pattern, in some cases, causes disagreements between experts, which is worrisome since an inaccurate diagnosis can bring complications to the infant. Despite the difficulties in visually identifying hypsarrhythmia, options of computerized assistance are scarce. Aiming to collaborate with the recognition of this electropathological pattern, we propose in this paper a mathematical index that can help electroencephalography experts to identify hypsarrhythmia. We performed hypothesis tests that indicated significant differences in the groups under analysis, where the p-values were found to be extremely small.<\/jats:p>","DOI":"10.3390\/e21030232","type":"journal-article","created":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T03:29:21Z","timestamp":1551410961000},"page":"232","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Identification of Hypsarrhythmia in Children with Microcephaly Infected by Zika Virus"],"prefix":"10.3390","volume":"21","author":[{"given":"Gean Carlos","family":"Sousa","sequence":"first","affiliation":[{"name":"Department of Electrical Engineering, Federal University of Maranh\u00e3o (UFMA), S\u00e3o Lu\u00eds-MA 65080-805, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio M.","family":"Queiroz","sequence":"additional","affiliation":[{"name":"Brain Institute, Federal University of Rio Grande do Norte, Natal 59078-970, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patr\u00edcia","family":"Sousa","sequence":"additional","affiliation":[{"name":"Department of Medicine, University Hospital of the Federal University of Maranh\u00e3o, S\u00e3o Lu\u00eds-MA 65080-805, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priscila","family":"Lima","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Federal University of Maranh\u00e3o (UFMA), S\u00e3o Lu\u00eds-MA 65080-805, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ant\u00f4nio Augusto Moura da","family":"Silva","sequence":"additional","affiliation":[{"name":"Department of Public Health, Federal University of Maranh\u00e3o, S\u00e3o Lu\u00eds-MA 65080-805, Brasil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0702-6783","authenticated-orcid":false,"given":"Nilviane","family":"Pires","sequence":"additional","affiliation":[{"name":"Program in Biotechnology, Center for Biological Sciences and Health, Federal University of Maranh\u00e3o (UFMA), S\u00e3o Lu\u00eds-MA 65080-805, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1654-0955","authenticated-orcid":false,"given":"Allan Kardec","family":"Barros","sequence":"additional","affiliation":[{"name":"Department of Electrical Engineering, Federal University of Maranh\u00e3o (UFMA), S\u00e3o Lu\u00eds-MA 65080-805, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2019,2,28]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.clinph.2016.11.004","article-title":"Sleep EEG patterns in infants with congenital Zika virus syndrome","volume":"128","author":"Carvalho","year":"2017","journal-title":"Clin. 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