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A prediction regarding the internal structure of the composition tetrahedron (presence\/absence of one\/two internal singular points) was made using thermodynamic modeling in AspenPlus V.10.0. The existence of two internal quaternary azeotropes (of node type with a minimum boiling point and of saddle type) was confirmed as a result of a full-scale experiment. Thermodynamic-topological analysis of the structure of phase equilibrium diagrams was carried out to confirm the correctness of the diagram construction.<\/jats:p>","DOI":"10.3390\/e25070980","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T02:19:20Z","timestamp":1687832360000},"page":"980","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Experimental Evidence for Double Quaternary Azeotropy\u2019s Existence"],"prefix":"10.3390","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5675-5777","authenticated-orcid":false,"given":"Anastasia","family":"Frolkova","sequence":"first","affiliation":[{"name":"Lomonosov Institute of Fine Chemical Technologies, MIREA\u2014Russian Technological University, 119454 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeriy","family":"Zhuchkov","sequence":"additional","affiliation":[{"name":"Lomonosov Institute of Fine Chemical Technologies, MIREA\u2014Russian Technological University, 119454 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alla","family":"Frolkova","sequence":"additional","affiliation":[{"name":"Lomonosov Institute of Fine Chemical Technologies, MIREA\u2014Russian Technological University, 119454 Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2023,6,26]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1134\/S0040579520020049","article-title":"Thermodynamic and topological analysis of phase diagrams of quaternary systems with internal singular points","volume":"54","author":"Frolkova","year":"2020","journal-title":"Theor. 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