{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T02:38:53Z","timestamp":1784255933359,"version":"3.55.0"},"reference-count":6,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EBJ"],"abstract":"<jats:p>Secondary infections of skin grafts pose a continuous problem in burn patients, very often leading to loss of transplanted skin grafts and making multiple surgical revisions necessary. We present a case report about persisting Pseudomonas aeruginosa infection in burn patients with known diabetes. The burn wounds in lower extremities required repeated debridements, multiple skin grafting attempts and finally an application of the dermal scaffold NovoSorb BTM. With these measures, we managed to undertake a successful reconstruction of infected burn defects and pre-vent an amputation. We concluded that the NovoSorb BTM could be seen as an additional promising tool in a burn surgery armamentarium. In cases where radical surgical wound decontamination is not possible without risking the loss of the limb, the application of NovoSorb BTM over a contaminated field can win extra time for topical infection treatment and additionally provide an excellent skin grafting ground.<\/jats:p>","DOI":"10.3390\/ebj3010004","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T04:15:25Z","timestamp":1641960925000},"page":"27-33","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Limb Salvage through Intermediary Wound Coverage with Acellular Dermal Matrix Template after Persistent Pseudomonas Aeruginosa Infection in a Burn Patient"],"prefix":"10.3390","volume":"3","author":[{"given":"Mateusz","family":"G\u0142adysz","sequence":"first","affiliation":[{"name":"Burn Center, Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hanover Medical School, Carl-Neuberg-Stra\u00dfe 1, 30625 Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9224-5475","authenticated-orcid":false,"given":"Vincent","family":"M\u00e4rz","sequence":"additional","affiliation":[{"name":"Burn Center, Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hanover Medical School, Carl-Neuberg-Stra\u00dfe 1, 30625 Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Ruemke","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Carl-Neuberg-Stra\u00dfe 1, 30625 Hannover, Germany"},{"name":"Lower Saxony Centre for Biomedical Engineering, Implant Research and Development, Stadtfelddam 34, 30625 Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgenii","family":"Rubalskii","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Carl-Neuberg-Stra\u00dfe 1, 30625 Hannover, Germany"},{"name":"Lower Saxony Centre for Biomedical Engineering, Implant Research and Development, Stadtfelddam 34, 30625 Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Maria","family":"Vogt","sequence":"additional","affiliation":[{"name":"Burn Center, Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hanover Medical School, Carl-Neuberg-Stra\u00dfe 1, 30625 Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2662-6290","authenticated-orcid":false,"given":"Nicco","family":"Krezdorn","sequence":"additional","affiliation":[{"name":"Burn Center, Department of Plastic, Aesthetic, Hand and Reconstructive Surgery, Hanover Medical School, Carl-Neuberg-Stra\u00dfe 1, 30625 Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2022,1,12]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1473-3099(18)30482-1","article-title":"Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): A randomised, controlled, double-blind phase 1\/2 trial","volume":"19","author":"Jault","year":"2019","journal-title":"Lancet Infect. Dis."},{"key":"ref_2","first-page":"221","article-title":"Bacteriophage Method of Treatment of Infected Wounds","volume":"37","author":"Albee","year":"1932","journal-title":"Cal. West Med."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"212527","DOI":"10.7573\/dic.212527","article-title":"How to manage Pseudomonas aeruginosa infections","volume":"7","author":"Bassetti","year":"2018","journal-title":"Drugs Context"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1016\/j.bjps.2020.05.067","article-title":"A consecutive case series of defects reconstructed using NovoSorb\u00ae Biodegradable Temporising Matrix: Initial experience and early results","volume":"73","author":"Solanki","year":"2020","journal-title":"J. Plast. Reconstr. 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Engl."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.burns.2016.01.028","article-title":"Artificial dermal templates: A comparative study of NovoSorb\u2122 Biodegradable Temporising Matrix (BTM) and Integra\u00ae Dermal Regeneration Template (DRT)","volume":"42","author":"Cheshire","year":"2016","journal-title":"Burns"}],"container-title":["European Burn Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2673-1991\/3\/1\/4\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T13:27:18Z","timestamp":1760362038000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2673-1991\/3\/1\/4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,12]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,3]]}},"alternative-id":["ebj3010004"],"URL":"https:\/\/doi.org\/10.3390\/ebj3010004","relation":{},"ISSN":["2673-1991"],"issn-type":[{"value":"2673-1991","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,12]]}}}