{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T02:49:38Z","timestamp":1760150978999,"version":"build-2065373602"},"reference-count":51,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T00:00:00Z","timestamp":1644537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003503","name":"Nederlandse Brandwonden Stichting","doi-asserted-by":"publisher","award":["12.105","17.102"],"award-info":[{"award-number":["12.105","17.102"]}],"id":[{"id":"10.13039\/501100003503","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["EBJ"],"abstract":"<jats:p>A proxy-assessment of health-related quality of life (HRQL) may be an alternative for burn patients who are medically unable to self-report shortly after being admitted to the hospital. This study examined the patient\u2013partner agreement on the recalled pre-injury HRQL of burn patients. In a multi-centre study of 117 patient\u2013partner pairs, the recalled pre-burn HRQL was assessed with the EQ-5D-3L + Cognition during the acute phase following the burns. Agreement was evaluated with Kappa and ICC statistics. Burn severity and PTSD symptoms were assessed as potential predictors of disagreement. The results showed that pre-burn EQ-Index scores were similar to population norms, whereas the EQ Visual Analog Scale (EQ-VAS) scores of patients were significantly higher. Agreement varied across EQ-5D domains and, after adjusting for prevalence, was substantial to almost perfect. Average agreement on the EQ-Index and EQ-VAS was, respectively, substantial and moderate, but differences between partners were larger at lower levels of HRQL, and specifically in the pain\/discomfort domain. Patient\u2013partner differences could not be explained by the patient\u2019s age or gender, number of surgeries, partner\u2019s presence at the burn event, or post-traumatic stress disorder (PTSD) symptoms of either the patient or partner. In conclusion, patient\u2013partner agreement is substantial and partner\u2013proxy reports of pre-burn EQ-5D domains and EQ-Index scores may be used to complement or serve as a substitute for the patient\u2019s assessment. Given the moderate agreement on the EQ-VAS, it may be less suited for proxy assessment.<\/jats:p>","DOI":"10.3390\/ebj3010011","type":"journal-article","created":{"date-parts":[[2022,2,13]],"date-time":"2022-02-13T21:08:43Z","timestamp":1644786523000},"page":"135-144","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pre-Burn Health-Related Quality of Life: Patient and Partner Perspectives"],"prefix":"10.3390","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4448-4812","authenticated-orcid":false,"given":"Elise","family":"Boersma-van Dam","sequence":"first","affiliation":[{"name":"Association of Dutch Burn Centres, 1941 AJ Beverwijk, The Netherlands"},{"name":"Department of Clinical Psychology, Utrecht University, 3584 CS Utrecht, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helma","family":"Hofland","sequence":"additional","affiliation":[{"name":"Association of Dutch Burn Centres, Maasstad Hospital, 3079 DZ Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alette","family":"de Jong","sequence":"additional","affiliation":[{"name":"Red Cross Hospital, 1942 LE Beverwijk, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Van Loey","sequence":"additional","affiliation":[{"name":"Department of Clinical Psychology, Utrecht University, 3584 CS Utrecht, The Netherlands"},{"name":"Association of Dutch Burn Centres, Maasstad Hospital, 3079 DZ Rotterdam, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1056\/NEJM199603283341306","article-title":"Assessment of Quality-of-Life Outcomes","volume":"334","author":"Testa","year":"1996","journal-title":"N. 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