{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:43:10Z","timestamp":1760060590694,"version":"build-2065373602"},"reference-count":41,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiologia"],"abstract":"<jats:p>Introduction: Patients with inflammatory bowel disease (IBD) are at increased risk of developing other autoimmune disorders due to possible shared genetic, environmental, and immunological mechanisms. While autoimmune diseases are frequently observed in patients with IBD, data quantifying their inpatient prevalence and their association with outcomes such as mortality remain limited. Methods: National Inpatient Sample (NIS) 2016\u20132020 and International Classification of Diseases 10th Version, Clinical Modification (ICD-10-CM) diagnosis codes were used to identify patients with IBD and autoimmune conditions. A multivariate logistic regression analysis to identify an association between various autoimmune diseases and various IBDs was performed. Results: The study population included 141,478,025 patients. An association was found between 24 autoimmune conditions and IBD. Conclusions: Our study identified autoimmune comorbidities that are more prevalent in IBD patients. We found that polymyositis, AIHA, ITP, and thrombotic microangiopathy are associated with a higher risk of in-hospital mortality. Psoriasis and hypothyroidism are associated with a lower risk of in-hospital mortality. Further studies are needed to explore the mechanisms responsible.<\/jats:p>","DOI":"10.3390\/epidemiologia6030052","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T09:24:41Z","timestamp":1756805081000},"page":"52","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Prevalence of Various Autoimmune Comorbidities in Patients with Inflammatory Bowel Disease"],"prefix":"10.3390","volume":"6","author":[{"given":"Bipneet","family":"Singh","sequence":"first","affiliation":[{"name":"Henry Ford Jackson, 159, W Michigan Ave, Jackson, MI 49201, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4320-8349","authenticated-orcid":false,"given":"Shivam","family":"Kalra","sequence":"additional","affiliation":[{"name":"Trident Medical Center, North Charleston, SC 29406, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tejasvini","family":"Khanna","sequence":"additional","affiliation":[{"name":"Department of Medicine, Maulana Azad Medical College, New Delhi 110002, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isha","family":"Kohli","sequence":"additional","affiliation":[{"name":"Graduate School of Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0058-2421","authenticated-orcid":false,"given":"Vikash","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Creighton University, Phoenix, AZ 85012, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8365-7240","authenticated-orcid":false,"given":"Aalam","family":"Sohal","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Creighton University, Phoenix, AZ 85012, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divyesh","family":"Sejpal","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, TX 77555, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1968","published-online":{"date-parts":[[2025,9,2]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1128\/CMR.15.1.79-94.2002","article-title":"Clinical Aspects and Pathophysiology of Inflammatory Bowel Disease","volume":"15","author":"Hendrickson","year":"2002","journal-title":"Clin. 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