{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:19:24Z","timestamp":1784038764258,"version":"3.55.0"},"reference-count":34,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T00:00:00Z","timestamp":1760140800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiologia"],"abstract":"<jats:p>Background and Objectives: Measles is a highly contagious but vaccine-preventable disease with significant morbidity in the European region, including Romania, especially in the post-COVID-19 era with low vaccination rates which no longer provide herd immunity. The current study aims to show how vaccination reduces the disease burden. Methods: A study using 29,148 cases with measles-compatible features in Romania from the 2020\u20132024 period was performed, analyzing symptoms, complications, and hospitalization rates comparatively between vaccinated and non-vaccinated groups. Results: Our findings show substantial hospitalization rates reduction among vaccinated cases with an over 12% decrease\u2014depending on the number of MMR doses\u2014as well as reduced severity of clinical features, but no significant effect on disease duration. Conclusions: MMR vaccination provides protection beyond primary disease prevention, as it reduces the disease burden among measles cases by reducing disease-related hospitalizations and improving clinical outcomes.<\/jats:p>","DOI":"10.3390\/epidemiologia6040063","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T08:34:26Z","timestamp":1760517266000},"page":"63","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Positive Impact of Vaccinal Status Among Notified Measles Cases in Romania in 2020\u20132024"],"prefix":"10.3390","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4739-9197","authenticated-orcid":false,"given":"Valerian-Ionu\u021b","family":"Stoian","sequence":"first","affiliation":[{"name":"Medical Department, Faculty of Medicine & Pharmacy, \u2018Dun\u0103rea de Jos\u2019 University of Gala\u021bi, 800008 Gala\u021bi, Romania"},{"name":"National Institute for Public Health, 050463 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iulia","family":"Chiscop","sequence":"additional","affiliation":[{"name":"Department of Clinical Surgery, Faculty of Medicine and Pharmacy, \u201cDunarea de Jos\u201d University, 800008 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4127-481X","authenticated-orcid":false,"given":"Aurora","family":"St\u0103nescu","sequence":"additional","affiliation":[{"name":"National Institute for Public Health, 050463 Bucharest, Romania"},{"name":"Medicine Faculty, \u2018Carol Davila\u2019 University of Medicine & Pharmacy, 050474 Bucharest, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana Daniela","family":"Ignat","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Medicine and Pharmacy, \u201cDunarea de Jos\u201d University, 800008 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-3466-4717","authenticated-orcid":false,"given":"Raisa Eloise","family":"Barbu","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Medicine and Pharmacy, \u201cDunarea de Jos\u201d University, 800008 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u0103d\u0103lina Nicoleta","family":"Matei","sequence":"additional","affiliation":[{"name":"Department of Dental Medicine, Faculty of Medicine and Pharmacy, \u201cDunarea de Jos\u201d University, 800008 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexia Anastasia \u0218tefania","family":"Balt\u0103","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Medicine and Pharmacy, \u201cDunarea de Jos\u201d University, 800008 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7602-8435","authenticated-orcid":false,"given":"Liliana","family":"Baroiu","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine, Faculty of Medicine and Pharmacy, \u201cDunarea de Jos\u201d University, 800008 Galati, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iulia","family":"Draghiev","sequence":"additional","affiliation":[{"name":"Medical Department, Faculty of Medicine & Pharmacy, \u2018Dun\u0103rea de Jos\u2019 University of Gala\u021bi, 800008 Gala\u021bi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela","family":"Debita","sequence":"additional","affiliation":[{"name":"Medical Department, Faculty of Medicine & Pharmacy, \u2018Dun\u0103rea de Jos\u2019 University of Gala\u021bi, 800008 Gala\u021bi, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2025,10,11]]},"reference":[{"key":"ref_1","unstructured":"ECDC (2025, August 03). 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Womens Dermatol."}],"container-title":["Epidemiologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2673-3986\/6\/4\/63\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T09:37:06Z","timestamp":1760521026000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2673-3986\/6\/4\/63"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,11]]},"references-count":34,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["epidemiologia6040063"],"URL":"https:\/\/doi.org\/10.3390\/epidemiologia6040063","relation":{},"ISSN":["2673-3986"],"issn-type":[{"value":"2673-3986","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,11]]}}}