{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T12:39:57Z","timestamp":1786711197270,"version":"build-2736575974"},"reference-count":38,"publisher":"MDPI AG","issue":"4","license":[{"start":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T00:00:00Z","timestamp":1786665600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Epidemiologia"],"abstract":"<jats:p>Background: This scoping review maps and synthesizes the scientific evidence on the epidemiological profile and determinants of sick leave and work-related accidents in Brazil, with an emphasis on studies using data from the Brazilian Federal Medical Expert Service of the Ministry of Social Security. Methods: Following the PRISMA-ScR guidelines and the JBI Manual for Evidence Synthesis, eight databases (SciELO, PubMed\/MEDLINE, Scopus, Web of Science, LILACS, CINAHL, PsycINFO, Embase) were searched for quantitative observational studies published between 2000 and 2025. Out of the 218 studies identified, 18 met the eligibility criteria. Results: Cross-sectional designs (66.7%) and ecological\/time-series designs (22.2%) predominated. The findings identified musculoskeletal disorders as the leading cause of work absence; mental disorders were the third leading cause, exhibiting an upward trend; and a significant influence of institutional factors, especially the Social Security Technical Epidemiological Nexus, on the observed patterns. Determinants operate at the individual, occupational\/organizational, and institutional levels. Conclusions: Empirical research on work disability in Brazil remains fragmented, providing limited capacity for causal inference. The findings support five priority areas: sectoral risk management, workplace mental health, territorial strategies for musculoskeletal disorders, sick leave trajectory policies, and data governance, all of which necessitate longitudinal and quasi-experimental studies to evaluate interventions and the impact of institutional changes.<\/jats:p>","DOI":"10.3390\/epidemiologia7040111","type":"journal-article","created":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T11:57:46Z","timestamp":1786708666000},"page":"111","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Work-Related Illnesses and Work Disability in Brazil: A Scoping Review of the Epidemiological Profile and Determinants of Sick Leave and Occupational Accidents"],"prefix":"10.3390","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1240-4702","authenticated-orcid":false,"given":"Luciano Garcia","family":"Louren\u00e7\u00e3o","sequence":"first","affiliation":[{"name":"Office of the Minister of State, Ministry of Social Security, Bras\u00edlia 70059-900, DF, Brazil"},{"name":"School of Nursing, Federal University of Rio Grande, Rio Grande 96200-400, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano Silveira Pacheco de","family":"Medeiros","sequence":"additional","affiliation":[{"name":"School of Nursing, Federal University of Rio Grande, Rio Grande 96200-400, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,8,14]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"e00031524","DOI":"10.1590\/0102-311xen031524","article-title":"Mental and behavioral disorders related to work in Brazil: Temporal trends and the impact of the Social Security Technical Nexus","volume":"40","author":"Fischer","year":"2024","journal-title":"Cad. Saude Publica"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s10926-024-10205-y","article-title":"Prognostic factors and models for predicting work absence in adults with musculoskeletal conditions consulting a healthcare practitioner: A systematic review","volume":"35","author":"Wainwright","year":"2025","journal-title":"J. Occup. Rehabil."},{"key":"ref_3","first-page":"e230623","article-title":"Incapacity for work due to mental and behavioral disorders in Brazilian social security: A temporal analysis","volume":"8","author":"Gomes","year":"2023","journal-title":"Perspect. Med. Leg. Pericia Med."},{"key":"ref_4","unstructured":"Brasil (2026, February 02). Lei n\u00ba 8.213, de 24 de Julho de 1991. Disp\u00f5e Sobre os Planos de Benef\u00edcios da Previd\u00eancia Social e d\u00e1 Outras Provid\u00eancias, Available online: https:\/\/www.planalto.gov.br\/ccivil_03\/leis\/l8213cons.htm."},{"key":"ref_5","unstructured":"Brasil (2026, February 02). Decreto n\u00ba 3.048, de 6 de Maio de 1999. Aprova o Regulamento da Previd\u00eancia Social e d\u00e1 Outras Provid\u00eancias, Available online: https:\/\/www.planalto.gov.br\/ccivil_03\/decreto\/d3048.htm."},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/ajim.20974","article-title":"Incidence of work and non-work related disability claims in Brazil","volume":"54","author":"Souza","year":"2011","journal-title":"Am. J. Ind. Med."},{"key":"ref_7","first-page":"e18275","article-title":"Desafios para concess\u00e3o do benef\u00edcio por incapacidade no Brasil","volume":"22","author":"Casarini","year":"2025","journal-title":"Cad. Pedagog."},{"key":"ref_8","unstructured":"Brasil (2026, February 02). Lei n\u00ba 11.430, de 26 de Dezembro de 2006. Disp\u00f5e Sobre a Utiliza\u00e7\u00e3o do Nexo T\u00e9cnico Epidemiol\u00f3gico\u2014NTEP para a Caracteriza\u00e7\u00e3o da Natureza da Incapacidade, Available online: https:\/\/www.planalto.gov.br\/ccivil_03\/_ato2004-2006\/2006\/lei\/l11430.htm."},{"key":"ref_9","unstructured":"Brasil (2026, February 02). Decreto n\u00ba 6.042, de 12 de Fevereiro de 2007. Altera o Regulamento da Previd\u00eancia Social, Aprovado pelo Decreto n\u00ba 3.048, de 6 de Maio de 1999, para Dispor Sobre o Nexo T\u00e9cnico Epidemiol\u00f3gico, Available online: https:\/\/www.planalto.gov.br\/ccivil_03\/_ato2007-2010\/2007\/decreto\/d6042.htm."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"e00191119","DOI":"10.1590\/0102-311x00191119","article-title":"Nexo T\u00e9cnico Epidemiol\u00f3gico Previdenci\u00e1rio (NTEP): Risco das sete atividades econ\u00f4micas e condi\u00e7\u00f5es incapacitantes mais frequentes, Brasil, 2000\u20132016","volume":"37","author":"Oliveira","year":"2021","journal-title":"Cad. Saude Publica"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1177\/21650799231193578","article-title":"Workplace psychosocial factors and their association with musculoskeletal disorders: A systematic review of longitudinal studies","volume":"71","author":"Bezzina","year":"2023","journal-title":"Workplace Health Saf."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"103434","DOI":"10.1016\/j.apergo.2021.103434","article-title":"A systematic overview on the risk effects of psychosocial work characteristics on musculoskeletal disorders, absenteeism, and workplace accidents","volume":"95","author":"Taibi","year":"2021","journal-title":"Appl. Ergon."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"e00141823","DOI":"10.1590\/0102-311xen141823","article-title":"Space-time analysis of work-related musculoskeletal disorders in Brazil: An ecological study","volume":"40","author":"Lima","year":"2024","journal-title":"Cad. Saude Publica"},{"key":"ref_14","first-page":"709","article-title":"Psychosocial occupational exposures and mental illness","volume":"119","author":"Seidler","year":"2022","journal-title":"Dtsch. Arztebl. Int."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Skr\u016bzkalne, I., Nagle, E., Se\u0146k\u0101ne, S., Rajevska, O., Nyberg, A., Zamalijeva, O., Ivanovs, A., and Reine, I. (2026). Psychosocial Work Factors, Well-Being, and Health Pathways to Sickness Absence: An Integrated GLM\u2013SEM Approach. Adm. Sci., 16.","DOI":"10.3390\/admsci16010007"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Knezevic, S., Gajic, T., Djonovic, N., Knezevic, S., Vukolic, D., Marinkovic, T., Janicijevic, N., Vasiljevic, D., Djordjevic, S., and Marinkovic, D. (2024). Sex-Specific Associations Between Lifestyle Factors and Sick Leave in the Serbian Working Population: Findings from the National Health Survey. Healthcare, 12.","DOI":"10.20944\/preprints202409.0845.v1"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Carstensen, T.B.W., Ravn, S.L., Andersen, T.E., S\u00e6ther, S.M.M., \u00d8rnb\u00f8l, E., Wellnitz, K.B., Kasch, H., and Frostholm, L. (2024). Do Acute Illness Perceptions Moderate the Association of Pre-Collision Welfare Benefits and Later Neck Pain or Disability Following Whiplash Trauma? A Prospective Multicentre Cohort Study. J. Clin. Med., 13.","DOI":"10.3390\/jcm13237072"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.25110\/arqsaude.v29i3.2025-11986","article-title":"Incapacidade para o trabalho devido a transtornos mentais entre trabalhadores e trabalhadoras da sa\u00fade no per\u00edodo pr\u00e9 e durante a pandemia da COVID-19","volume":"29","author":"Cruz","year":"2025","journal-title":"Arq. Cienc. Saude UNIPAR"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"e3768","DOI":"10.33362\/juridico.v14i1.3768","article-title":"Avalia\u00e7\u00e3o do perfil epidemiol\u00f3gico e social dos afastamentos do trabalho da popula\u00e7\u00e3o economicamente ativa","volume":"14","author":"Adami","year":"2025","journal-title":"Ponto Vista Jurid."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/1364557032000119616","article-title":"Scoping studies: Towards a methodological framework","volume":"8","author":"Arksey","year":"2005","journal-title":"Int. J. Soc. Res. Methodol."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"467","DOI":"10.7326\/M18-0850","article-title":"PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation","volume":"169","author":"Tricco","year":"2018","journal-title":"Ann. Intern. Med."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1590\/S0034-89102002000300013","article-title":"Morbidade subjacente \u00e0 concess\u00e3o de benef\u00edcios por incapacidade tempor\u00e1ria para o trabalho","volume":"36","author":"Boff","year":"2002","journal-title":"Rev. Saude Publica"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"3427","DOI":"10.1590\/S1413-81232011000900010","article-title":"Dist\u00farbios osteomusculares relacionados ao trabalho: O perfil dos trabalhadores em benef\u00edcio previdenci\u00e1rio em Diamantina (MG, Brasil)","volume":"16","author":"Nunes","year":"2011","journal-title":"Cienc. Saude Coletiva"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1590\/S1806-37132012000500003","article-title":"Preval\u00eancia e dura\u00e7\u00e3o dos benef\u00edcios aux\u00edlio-doen\u00e7a decorrentes de asma no Brasil em 2008","volume":"38","author":"Ildefonso","year":"2012","journal-title":"J. Bras. Pneumol."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1590\/S1806-37132009000100007","article-title":"Prevalence of temporary social security benefits due to respiratory disease in Brazil","volume":"35","author":"Ildefonso","year":"2009","journal-title":"J. Bras. Pneumol."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"3157","DOI":"10.1590\/S1413-81232013001100006","article-title":"Incapacidade para o trabalho: An\u00e1lise dos benef\u00edcios aux\u00edlio-doen\u00e7a concedidos no estado de Rond\u00f4nia","volume":"18","author":"Jakobi","year":"2013","journal-title":"Cienc. Saude Coletiva"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1590\/S0034-89102012005000025","article-title":"Fatores associados \u00e0 dura\u00e7\u00e3o dos benef\u00edcios por incapacidade: Um estudo de coorte","volume":"46","author":"Souza","year":"2012","journal-title":"Rev. Saude Publica"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1590\/S0034-8910.2014048004802","article-title":"Adoecimento mental incapacitante: Benef\u00edcios previdenci\u00e1rios no Brasil entre 2008\u20132011","volume":"48","author":"Fischer","year":"2014","journal-title":"Rev. Saude Publica"},{"key":"ref_29","doi-asserted-by":"crossref","unstructured":"Silva-J\u00fanior, J.S., and Fischer, F.M. (2014). Long-term sickness absence due to mental disorders is associated with individual features and psychosocial work conditions. PLoS ONE, 9.","DOI":"10.1371\/journal.pone.0115885"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"e000003","DOI":"10.1136\/bmjopen-2011-000003","article-title":"Work disability benefits due to musculoskeletal disorders among Brazilian private sector workers","volume":"1","author":"Vieira","year":"2011","journal-title":"BMJ Open"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1590\/1980-5497201500010015","article-title":"Sinovite e tenossinovite no Brasil: Uma an\u00e1lise dos benef\u00edcios aux\u00edlio-doen\u00e7a","volume":"18","author":"Andrade","year":"2015","journal-title":"Rev. Bras. Epidemiol."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1590\/0102-311X00087213","article-title":"Benef\u00edcios aux\u00edlio-doen\u00e7a concedidos aos trabalhadores empregados no ramo de carne e pescado no Brasil em 2008","volume":"31","author":"Jakobi","year":"2015","journal-title":"Cad. Saude Publica"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"185","DOI":"10.5327\/Z1679443520180198","article-title":"Benef\u00edcios por doen\u00e7as cardiovasculares na cidade do Recife, Pernambuco, no quinqu\u00eanio 2011\u20132015","volume":"16","author":"Vianna","year":"2018","journal-title":"Rev. Bras. Med. Trab."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1590\/1980-5497201500040005","article-title":"Afastamento do trabalho por transtornos mentais e estressores psicossociais ocupacionais","volume":"18","author":"Fischer","year":"2015","journal-title":"Rev. Bras. Epidemiol."},{"key":"ref_35","doi-asserted-by":"crossref","unstructured":"Coelho, R.M., Nunes, M.A.P., Gomes, C.V.C., Viana, I.S., and Silva, A.M. (2020). Time trends and social security burden of temporary work disability due to chronic venous disease in Brazil. BMC Public Health, 20.","DOI":"10.1186\/s12889-020-08563-2"},{"key":"ref_36","doi-asserted-by":"crossref","unstructured":"Kovacevic, N., \u017dagar, T., Homar, V., Pelhan, B., Sremec, M., Rozman, T., and Besic, N. (2024). Benefits of Early Integrated and Vocational Rehabilitation in Breast Cancer on Work Ability, Sick Leave Duration, and Disability Rates. Healthcare, 12.","DOI":"10.3390\/healthcare12232433"},{"key":"ref_37","first-page":"e9147","article-title":"Return-to-Work challenges from workers\u2019 perspective after work-related sick leave","volume":"49","author":"Freitas","year":"2025","journal-title":"Saude Debate"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"}],"container-title":["Epidemiologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2673-3986\/7\/4\/111\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T12:12:00Z","timestamp":1786709520000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2673-3986\/7\/4\/111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,14]]},"references-count":38,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2026,8]]}},"alternative-id":["epidemiologia7040111"],"URL":"https:\/\/doi.org\/10.3390\/epidemiologia7040111","relation":{},"ISSN":["2673-3986"],"issn-type":[{"value":"2673-3986","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,14]]}}}