{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:20:48Z","timestamp":1793420448953,"version":"4.5.0"},"reference-count":62,"publisher":"MDPI AG","issue":"3","license":[{"start":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T00:00:00Z","timestamp":1615334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>Chickpea (Cicer arietinum L.) from Valle Agricola is a legume cultivated in Southern Italy whose intake is strictly linked to rural traditions. In order to get new biochemical insight on this landrace and to promote its consumption and marketing, nutritional values (moisture content, total proteins, lipids, total and free amino acids) and metabolic traits are deeply investigated. Valle Agricola chickpea is nutritionally rich in proteins (19.70 g\/100 g) and essential amino acids (7.12 g\/100 g; ~40% of total). Carbohydrates, whose identity was unraveled by means of UHPLC-HR MS\/MS analysis, were almost 60% of chemicals. In particular, a di-galactosylglycerol, a pinitol digalactoside, and a galactosylciceritol were found as constitutive, together with different raffinose-series oligosaccharides. Although lipids were the less constitutive compounds, glycerophospholipids were identified, while among free fatty acids linoleic acid (C18:2) was the most abundant, followed by oleic (C18:1) and palmitic (C16:0) acids. Isoflavones and hydroxybenzoic acid derivatives were also detected. Valle Agricola chickpeas showed very good levels of several mineral nutrients, especially magnesium (164 mg\/100 g), potassium (748 mg\/100 g), calcium (200 mg\/100 g), zinc (4.20 mg\/100 g) and manganese (0.45 mg\/100 g). The boiling process favorably decreases anti-trypsin and anti-chymotrypsin activities, depleting this precious seed of its intrinsic antinutritional factors.<\/jats:p>","DOI":"10.3390\/foods10030583","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T13:27:20Z","timestamp":1615382840000},"page":"583","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Valle Agricola Chickpeas: Nutritional Profile and Metabolomics Traits of a Typical Landrace Legume from Southern Italy"],"prefix":"10.3390","volume":"10","author":[{"given":"Nicola","family":"Landi","sequence":"first","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3150-7886","authenticated-orcid":false,"given":"Simona","family":"Piccolella","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2219-2424","authenticated-orcid":false,"given":"Sara","family":"Ragucci","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8645-3294","authenticated-orcid":false,"given":"Shadab","family":"Faramarzi","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Clemente","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8315-3154","authenticated-orcid":false,"given":"Stefania","family":"Papa","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3804-9809","authenticated-orcid":false,"given":"Severina","family":"Pacifico","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9595-9665","authenticated-orcid":false,"given":"Antimo","family":"Di Maro","sequence":"additional","affiliation":[{"name":"Department of Environmental, Biological and Pharmaceutical Sciences and Technologies (DiSTABiF), University of Campania Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2021,3,10]]},"reference":[{"key":"ref_1","first-page":"414","article-title":"The Mediterranean Diet, recognized by UNESCO as a cultural heritage of humanity","volume":"7","author":"Saulle","year":"2010","journal-title":"Ital. J. Public Health"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1093\/oxfordjournals.aje.a114480","article-title":"The diet and 15-year death rate in the seven countries study","volume":"124","author":"Keys","year":"1986","journal-title":"Am. J. Epidemiol."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"805","DOI":"10.2147\/JMDH.S219875","article-title":"The Mediterranean Diet and Cardioprotection: Historical Overview and Current Research","volume":"12","author":"Minelli","year":"2019","journal-title":"J. Multidiscip. Healthc."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1017\/S1368980013003169","article-title":"Mediterranean diet and health status: An updated meta-analysis and a proposal for a literature-based adherence score","volume":"17","author":"Sofi","year":"2014","journal-title":"Public Health Nutr."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1089\/jmf.2010.0244","article-title":"The mediterranean diet in cancer prevention: A review","volume":"14","author":"Kontou","year":"2011","journal-title":"J. Med. Food"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.4067\/S0034-98872017000100012","article-title":"Origin, components and mechanisms of action of the Mediterranean diet","volume":"145","author":"Urquiaga","year":"2017","journal-title":"Rev. Med. Chile"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1089\/jmf.2011.0238","article-title":"Nutritional quality of legumes, and their role in cardiometabolic risk prevention: A review","volume":"16","author":"Bouchenak","year":"2013","journal-title":"J. Med. Food"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1139\/apnm-2013-0557","article-title":"Nutritional and health benefits of pulses","volume":"39","author":"Mudryj","year":"2014","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"M\u00e9rillon, J.-M., and Ramawat, K.G. (2019). Plant Proteins from Legumes. Bioactive Molecules in Food, Springer International Publishing.","DOI":"10.1007\/978-3-319-78030-6"},{"key":"ref_10","doi-asserted-by":"crossref","unstructured":"Li, H., Li, J., Shen, Y., Wang, J., and Zhou, D. (2017). Legume Consumption and All-Cause and Cardiovascular Disease Mortality. BioMed Res. Int., 2017.","DOI":"10.1155\/2017\/8450618"},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Foyer, C.H., Lam, H.-M., Nguyen, H.T., Siddique, K.H.M., Varshney, R.K., Colmer, T.D., Cowling, W., Bramley, H., Mori, T.A., and Hodgson, J.M. (2016). Neglecting legumes has compromised human health and sustainable food production. Nat. Plants, 2.","DOI":"10.1038\/nplants.2016.112"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Knights, E.J., and Hobson, K.B. (2016). Chickpea Overview. Reference Module in Food Science, Elsevier.","DOI":"10.1016\/B978-0-08-100596-5.00035-4"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1079\/PGR200591","article-title":"Defining and identifying crop landraces","volume":"3","author":"Maxted","year":"2005","journal-title":"Plant Genet. Resour."},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"3155","DOI":"10.1039\/C5FO00604J","article-title":"Valle Agricola lentil, an unknown lentil (Lens culinaris Medik.) seed from Southern Italy as a novel antioxidant and prebiotic source","volume":"6","author":"Landi","year":"2015","journal-title":"Food Funct."},{"key":"ref_15","first-page":"149","article-title":"Nutritional values and radical scavenging capacities of grass pea (Lathyrus sativus L.) Seeds in valle agricola district, Italy","volume":"6","author":"Tamburino","year":"2012","journal-title":"Aust. J. Crop Sci."},{"key":"ref_16","first-page":"331","article-title":"Nutritional values and metabolic profile with and without boiled treatment of \u2018Gallo Matese\u2019 beans (Phaseolus vulgaris L.), a landrace from Southern Italy","volume":"16","author":"Landi","year":"2017","journal-title":"Acta Sci. Pol. Technol. Aliment."},{"key":"ref_17","unstructured":"(2019). Regione_Campania Prodotti tipici Regione Campania. Gazz. Uff., 60, 10\u201316."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Yadav, S.S., and Chen, W. (2007). Nutritional Value of Chickpea. Chickpea Breeding and Management, CABI.","DOI":"10.1079\/9781845932138.000"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Wallace, T.C., Murray, R., and Zelman, K.M. (2016). The Nutritional Value and Health Benefits of Chickpeas and Hummus. Nutrients, 8.","DOI":"10.3390\/nu8120766"},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"5388","DOI":"10.1002\/jsfa.8428","article-title":"Pioppino mushroom in southern Italy: An undervalued source of nutrients and bioactive compounds","volume":"97","author":"Landi","year":"2017","journal-title":"J. Sci. Food Agric."},{"key":"ref_21","unstructured":"AOAC (1997). Official Methods of Analysis, The Association of Official Analytical Chemists, Inc.. [17th ed.]."},{"key":"ref_22","first-page":"154","article-title":"Free amino acid profile in Malus domestica cv Annurca apples from the Campania region and other Italian vegetables","volume":"5","author":"Dosi","year":"2011","journal-title":"AJCS"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.foodres.2009.07.018","article-title":"Subunit, amino acid composition and in vitro digestibility of protein isolates from Chinese kabuli and desi chickpea (Cicer arietinum L.) cultivars","volume":"43","author":"Wang","year":"2010","journal-title":"Food Res. Int."},{"key":"ref_24","doi-asserted-by":"crossref","unstructured":"Landi, N., Ruocco, M.R., Ragucci, S., Aliotta, F., Nasso, R., Pedone, P.V., and Di Maro, A. (2020). Quinoa as source of type 1 ribosome inactivating proteins: A novel knowledge for a revision of its consumption. Food Chem.","DOI":"10.1016\/j.foodchem.2020.128337"},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Azarpazhooh, E., and Boye, J.I. (2012). Composition of Processed Dry Beans and Pulses. Dry Beans and Pulses Production, Processing and Nutrition, Blackwell Publishing Ltd.","DOI":"10.1002\/9781118448298.ch5"},{"key":"ref_26","unstructured":"CREA (2020, September 20). Centro di Ricerca per Gli Alimenti e la Nutrizione. Available online: http:\/\/nut.entecra.it\/."},{"key":"ref_27","doi-asserted-by":"crossref","unstructured":"Rizzello, C.G., Hern\u00e1ndez-Ledesma, B., Fern\u00e1ndez-Tom\u00e9, S., Curiel, J.A., Pinto, D., Marzani, B., Coda, R., and Gobbetti, M. (2015). Italian legumes: Effect of sourdough fermentation on lunasin-like polypeptides. Microb. Cell Fact., 14.","DOI":"10.1186\/s12934-015-0358-6"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/s10722-012-9884-9","article-title":"Characterization of Italian chickpea (Cicer arietinum L.) germplasm by multidisciplinary approach","volume":"60","author":"Zaccardelli","year":"2013","journal-title":"Genet. Resour. Crop Evol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1745-4557.2006.00074.x","article-title":"Variation and relationships among some nutritional traits in Sicilian genotypes of chickpea (Cicer arietinum L.)","volume":"29","year":"2006","journal-title":"J. Food Qual."},{"key":"ref_30","doi-asserted-by":"crossref","unstructured":"Winter, G., Todd, C.D., Trovato, M., Forlani, G., and Funck, D. (2015). Physiological implications of arginine metabolism in plants. Front. Plant Sci., 6.","DOI":"10.3389\/fpls.2015.00534"},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.foodchem.2015.07.001","article-title":"Purification of free arginine from chickpea (Cicer arietinum) seeds","volume":"192","author":"Alaiz","year":"2016","journal-title":"Food Chem."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1104\/pp.88.2.435","article-title":"Identification of l-Tryptophan as an Endogenous Inhibitor of Embryo Germination in White Wheat","volume":"88","author":"Morris","year":"1988","journal-title":"Plant Physiol."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/j.foodchem.2006.07.045","article-title":"Protein and non-protein (free and protein-bound) tryptophan in legume seeds","volume":"103","author":"Comai","year":"2007","journal-title":"Food Chem."},{"key":"ref_34","first-page":"6","article-title":"Plant food anti-nutritional factors and their reduction strategies: An overview","volume":"2","author":"Samtiya","year":"2020","journal-title":"FPPN"},{"key":"ref_35","unstructured":"Muhammad, S., and Mark, A.U. (2012). Chemistry and Implications of Antinutritional Factors in Dry Beans and Pulses. Dry Beans and Pulses Production, Processing and Nutrition, John Wiley & Sons, Inc."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/1750-3841.13985","article-title":"Inactivation Methods of Trypsin Inhibitor in Legumes: A Review","volume":"83","year":"2018","journal-title":"J. Food Sci."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1002\/fsn3.846","article-title":"Fermentation and germination improve nutritional value of cereals and legumes through activation of endogenous enzymes","volume":"6","author":"Nkhata","year":"2018","journal-title":"Food Sci. Nutr."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S1382-6689(02)00156-4","article-title":"Heavy metals in soil, vegetables and fruits in the endemic upper gastrointestinal cancer region of Turkey","volume":"13","author":"Kilicel","year":"2003","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"ref_39","unstructured":"(2021, January 08). Regione_Campania Regional Agro-Meteorological Center. Available online: http:\/\/agricoltura.regione.campania.it\/meteo\/agrometeo.htm."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1038\/s41598-019-38702-8","article-title":"Comparative Physiological and Metabolic Analysis Reveals a Complex Mechanism Involved in Drought Tolerance in Chickpea (Cicer arietinum L.) Induced by PGPR and PGRs","volume":"9","author":"Khan","year":"2019","journal-title":"Sci. Rep."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00217-011-1495-8","article-title":"Phytic acid and mineral micronutrients in field-grown chickpea (Cicer arietinum L.) cultivars from western Canada","volume":"233","author":"Bueckert","year":"2011","journal-title":"Eur. Food Res. Technol."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.2135\/cropsci2013.08.0568","article-title":"Mineral Micronutrient Content of Cultivars of Field Pea, Chickpea, Common Bean, and Lentil Grown in Saskatchewan, Canada","volume":"54","author":"Ray","year":"2014","journal-title":"Crop Sci."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1002\/rcm.4042","article-title":"Glycerophospholipid profiling by high-performance liquid chromatography\/mass spectrometry using exact mass measurements and multi-stage mass spectrometric fragmentation experiments in parallel","volume":"23","author":"Hein","year":"2009","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1039\/C5AY00776C","article-title":"Fragmentation patterns of five types of phospholipids by ultra-high-performance liquid chromatography electrospray ionization quadrupole time-of-flight tandem mass spectrometry","volume":"8","author":"Pi","year":"2016","journal-title":"Anal. Methods"},{"key":"ref_45","doi-asserted-by":"crossref","unstructured":"Phuong, D.L., Toan, T.Q., Dang, L.P., Imbs, A.B., Long, P.Q., Thang, T.D., Matthaeus, B., Bach, L.G., and Bui, L.M. (2019). Lipid isolation process and study on some molecular species of polar lipid isolated from seed of Madhuca ellitica. Processes, 7.","DOI":"10.3390\/pr7060375"},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0308-8146(98)00015-6","article-title":"Polar lipids of defatted chickpea (Cicer arietinum L.) flour and protein isolates","volume":"63","author":"Clemente","year":"1998","journal-title":"Food Chem."},{"key":"ref_47","doi-asserted-by":"crossref","unstructured":"Obendorf, R.L., Horbowicz, M., and Lahuta, L.B. (2012). CHAPTER 11 Characterization of Sugars, Cyclitols and Galactosyl Cyclitols in Seeds by GC. Dietary Sugars: Chemistry, Analysis, Function and Effects, The Royal Society of Chemistry.","DOI":"10.1039\/9781849734929-00167"},{"key":"ref_48","first-page":"185","article-title":"Biochemistry and physiology of raffinose family oligosaccharides and galactosyl cyclitols in seeds","volume":"11","author":"Peterbauer","year":"2001","journal-title":"Seed Sci. Res."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.phytochem.2016.02.009","article-title":"Galactinol synthase enzyme activity influences raffinose family oligosaccharides (RFO) accumulation in developing chickpea (Cicer arietinum L.) seeds","volume":"125","author":"Gangola","year":"2016","journal-title":"Phytochemistry"},{"key":"ref_50","doi-asserted-by":"crossref","unstructured":"Arunraj, R., Skori, L., Kumar, A., Hickerson, N.M.N., Shoma, N.M.V., and Samuel, M.A. (2020). Spatial regulation of alpha-galactosidase activity and its influence on raffinose family oligosaccharides during seed maturation and germination in Cicer arietinum. Plant Signal. Behav., 15.","DOI":"10.1080\/15592324.2019.1709707"},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.lwt.2017.01.040","article-title":"Effects of ciceritol from chickpeas on human colonic microflora and the production of short chain fatty acids by in vitro fermentation","volume":"79","author":"Zhang","year":"2017","journal-title":"LWT"},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"17751","DOI":"10.1039\/C4RA13155J","article-title":"Profiling of phenolic and other compounds from Egyptian cultivars of chickpea (Cicer arietinum L.) and antioxidant activity: A comparative study","volume":"5","author":"Mekky","year":"2015","journal-title":"RSC Adv."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.1021\/jf5057524","article-title":"Isoflavone content and composition in chickpea (Cicer arietinum L.) sprouts germinated under different conditions","volume":"63","author":"Gao","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.jff.2015.12.012","article-title":"Isoflavones in chickpea (Cicer arietinum) protein concentrates","volume":"21","author":"Alaiz","year":"2016","journal-title":"J. Funct. Foods"},{"key":"ref_55","doi-asserted-by":"crossref","unstructured":"de Camargo, A.C., Favero, B.T., Morzelle, M.C., Franchin, M., Alvarez-Parrilla, E., de la Rosa, L.A., Geraldi, M.V., Mar\u00f3stica J\u00fanior, M.R., Shahidi, F., and Schwember, A.R. (2019). Is Chickpea a Potential Substitute for Soybean? Phenolic Bioactives and Potential Health Benefits. Int. J. Mol. Sci., 20.","DOI":"10.3390\/ijms20112644"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/aps.2012.160","article-title":"Assessment of the estrogenic activities of chickpea (Cicer arietinum L.) sprout isoflavone extract in ovariectomized rats","volume":"34","author":"Ma","year":"2013","journal-title":"Acta Pharmacol. Sin."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1574-6968.2000.tb09353.x","article-title":"Biotransformation of the isoflavonoids biochanin A, formononetin, and glycitein by Eubacterium limosum","volume":"192","author":"Hur","year":"2000","journal-title":"FEMS Microbiol. Lett."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"4783","DOI":"10.1021\/jf025549r","article-title":"Metabolism of biochanin A and formononetin by human liver microsomes in vitro","volume":"50","author":"Tolleson","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/j.foodchem.2007.05.004","article-title":"Nutritional and compositional study of Desi chickpea (Cicer arietinum L.) cultivars grown in Punjab, Pakistan","volume":"105","author":"Iqbal","year":"2007","journal-title":"Food Chem."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/jsfa.6702","article-title":"Valorization of traditional foods: Nutritional and bioactive properties of Cicer arietinum L. and Lathyrus sativus L. pulses","volume":"95","author":"Sarmento","year":"2015","journal-title":"J. Sci. Food Agric."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1080\/10408398.2012.687418","article-title":"Chickpeas\u2014Composition, nutritional value, health benefits, application to bread and snacks: A review","volume":"55","author":"Nebesny","year":"2015","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"ref_62","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.foodchem.2015.10.063","article-title":"Legume seeds and colorectal cancer revisited: Protease inhibitors reduce MMP-9 activity and colon cancer cell migration","volume":"197","author":"Lima","year":"2016","journal-title":"Food Chem."}],"container-title":["Foods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-8158\/10\/3\/583\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T05:33:28Z","timestamp":1760160808000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-8158\/10\/3\/583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,10]]},"references-count":62,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3]]}},"alternative-id":["foods10030583"],"URL":"https:\/\/doi.org\/10.3390\/foods10030583","relation":{},"ISSN":["2304-8158"],"issn-type":[{"value":"2304-8158","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,10]]}}}