{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T21:04:33Z","timestamp":1793826273621,"version":"4.6.1"},"reference-count":47,"publisher":"MDPI AG","issue":"23","license":[{"start":{"date-parts":[[2024,11,24]],"date-time":"2024-11-24T00:00:00Z","timestamp":1732406400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Goi\u00e1s (FAPEG-GO)","award":["202110267000904"],"award-info":[{"award-number":["202110267000904"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>The inappropriate use of antimicrobials in dairy animals can lead to residues in raw milk and in dairy products. Foods containing residues of this nature, whether in the short, medium, or long term, cause serious health harm. Absence of these compounds in foods should be a premise for declaring safety. This systematic review aimed to identify the antibiotic residues most frequently found in raw bovine milk and the methodologies used to detect such residues over the ten years from 2013 to 2023. PRISMA guidelines for systematic reviews were followed, by searching the Web of Science, PubMed Central, Scopus, and Springer databases. The search strategy identified 248 articles, and after applying the selection and quality assessment criteria, 16 studies were selected. The number of samples analyzed was 411,530, of which 0.21% tested positive for some type of antibiotic. Eight classes and 38 different types of antibiotics were identified. The most common class was tetracycline, with emphasis on sulfonamides and quinolones, which have shown increasing prevalence among residues in milk in recent years. A total of 56.25% of the studies employed rapid kits to detect residues, 18.75% chromatography, and 25% both techniques. Antibiotic residues in bovine raw milk should be a great concern for animal, environmental, and human health.<\/jats:p>","DOI":"10.3390\/foods13233758","type":"journal-article","created":{"date-parts":[[2024,11,25]],"date-time":"2024-11-25T06:25:19Z","timestamp":1732515919000},"page":"3758","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Antibiotic Residues in Raw Cow\u2019s Milk: A Systematic Review of the Last Decade"],"prefix":"10.3390","volume":"13","author":[{"given":"Lucyana Vieira","family":"Costa","sequence":"first","affiliation":[{"name":"Universidade Estadual de Goi\u00e1s, Campus Sul Ipameri, Ipameri 75780-000, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8753-1020","authenticated-orcid":false,"given":"Clarice","family":"Gebara","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5887-5526","authenticated-orcid":false,"given":"Ozana de F\u00e1tima","family":"Zacaroni","sequence":"additional","affiliation":[{"name":"Departamento de Zootecnia, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0613-6780","authenticated-orcid":false,"given":"Natylane Eufransino","family":"Freitas","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriele Nascimento da","family":"Silva","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9942-860X","authenticated-orcid":false,"given":"Cristiano Sales","family":"Prado","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8357-6969","authenticated-orcid":false,"given":"Iolanda Aparecida","family":"Nunes","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ria Quintana","family":"Cavicchioli","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francine Oliveira Souza","family":"Duarte","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2060-5632","authenticated-orcid":false,"given":"Moacir Evandro","family":"Lage","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiane Rodrigues de","family":"Alencar","sequence":"additional","affiliation":[{"name":"Escola de Agronomia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruna Aparecida Souza","family":"Machado","sequence":"additional","affiliation":[{"name":"SENAI Instituto de Inova\u00e7\u00e3o (ISI) Sistemas Avan\u00e7ados em Sa\u00fade (CIMATEC ISI SAS), SENAI CIMATEC, Centro Universit\u00e1rio, Salvador 41650-010, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharine Val\u00e9ria Saraiva","family":"Hodel","sequence":"additional","affiliation":[{"name":"SENAI Instituto de Inova\u00e7\u00e3o (ISI) Sistemas Avan\u00e7ados em Sa\u00fade (CIMATEC ISI SAS), SENAI CIMATEC, Centro Universit\u00e1rio, Salvador 41650-010, Bahia, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0727-5651","authenticated-orcid":false,"given":"C\u00edntia","family":"Minafra","sequence":"additional","affiliation":[{"name":"Centro de Pesquisa em Alimentos, Escola de Veterin\u00e1ria e Zootecnia, Campus Samambaia da Universidade Federal de Goi\u00e1s, Goi\u00e2nia 74690-900, Goi\u00e1s, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,11,24]]},"reference":[{"key":"ref_1","unstructured":"Food and Agriculture Organization of the United Nations (FAO) (2024). 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