{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:44:51Z","timestamp":1792043091138,"version":"4.4.0"},"reference-count":172,"publisher":"MDPI AG","issue":"24","license":[{"start":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T00:00:00Z","timestamp":1734912000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Universidad Autonoma de Baja California (UABC)","award":["304\/2\/C\/6\/23"],"award-info":[{"award-number":["304\/2\/C\/6\/23"]}]},{"name":"Universidad Autonoma de Baja California (UABC)","award":["CF-2023-G-119"],"award-info":[{"award-number":["CF-2023-G-119"]}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Humanidades, Ciencia y Tecnolog\u00eda (CONAHCyT)","doi-asserted-by":"publisher","award":["304\/2\/C\/6\/23"],"award-info":[{"award-number":["304\/2\/C\/6\/23"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Humanidades, Ciencia y Tecnolog\u00eda (CONAHCyT)","doi-asserted-by":"publisher","award":["CF-2023-G-119"],"award-info":[{"award-number":["CF-2023-G-119"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>Type 2 diabetes mellitus (T2DM) and cancer are significant contributors to morbidity and mortality worldwide. Recent studies have increasingly highlighted the potential of phytochemicals found in plants and plant-based foods for preventing and treating these chronic diseases. Mexico\u2019s agrobiodiversity provides a valuable resource for phytochemistry. This review presents an examination of essential phytochemicals found in plants and foods within Mexican agrobiodiversity that have shown promising anti-cancer and anti-diabetic properties, including their roles as antioxidants, insulin sensitizers, and enzyme inhibitors. Notable compounds identified include flavonoids (such as quercetin and catechins), phenolic acids (chlorogenic, gallic, and caffeic acids), methylxanthines (like theobromine), xanthones (such as mangiferin), capsaicinoids (capsaicin), organosulfur compounds (like alliin), and various lipids (avocatins). Although these phytochemicals have shown promise in laboratory and animal studies, there is a significant scarcity of clinical trial data involving humans, underscoring an important area for future research.<\/jats:p>","DOI":"10.3390\/foods13244176","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T09:13:38Z","timestamp":1734945218000},"page":"4176","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Phytochemistry, Anti-cancer, and Anti-diabetic Properties of Plant-Based Foods from Mexican Agrobiodiversity: A Review"],"prefix":"10.3390","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6740-2069","authenticated-orcid":false,"given":"Adriana","family":"Garc\u00eda-Gurrola","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Psychology, Autonomous University of Baja California, Tijuana 22427, Baja California, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0472-0115","authenticated-orcid":false,"given":"Ana Laura","family":"Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Psychology, Autonomous University of Baja California, Tijuana 22427, Baja California, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6196-3607","authenticated-orcid":false,"given":"Abraham","family":"Wall-Medrano","sequence":"additional","affiliation":[{"name":"Biomedical Sciences Institute, Autonomous University of Ciudad Ju\u00e1rez, Ciudad Juaez 32300, Chihuahua, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco J.","family":"Olivas-Aguirre","sequence":"additional","affiliation":[{"name":"Biomedical Sciences Institute, Autonomous University of Ciudad Ju\u00e1rez, Ciudad Juaez 32300, Chihuahua, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estefania","family":"Ochoa-Ruiz","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Psychology, Autonomous University of Baja California, Tijuana 22427, Baja California, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7306-7685","authenticated-orcid":false,"given":"Alberto A.","family":"Escobar-Puentes","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Psychology, Autonomous University of Baja California, Tijuana 22427, Baja California, Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2024,12,23]]},"reference":[{"key":"ref_1","unstructured":"Magliano, D.J., and Boyko, E.J. 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