{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:00:47Z","timestamp":1792789247129,"version":"4.5.0"},"reference-count":142,"publisher":"MDPI AG","issue":"7","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011493","name":"Scientific Research Project of Taizhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["23nya12"],"award-info":[{"award-number":["23nya12"]}],"id":[{"id":"10.13039\/501100011493","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zhejiang Provincial Market Regulation Science and Technology Project","award":["XM2026011"],"award-info":[{"award-number":["XM2026011"]}]},{"name":"Zhejiang Provincial Market Regulation Science and Technology Project","award":["QN2025057"],"award-info":[{"award-number":["QN2025057"]}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LTGC23C200001"],"award-info":[{"award-number":["LTGC23C200001"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"award":["LTGC23C200001"],"award-info":[{"award-number":["LTGC23C200001"]}],"id":[{"id":"https:\/\/ror.org\/04aqat463","id-type":"ROR","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004863","name":"Research Project of Zhejiang Chinese Medical University","doi-asserted-by":"publisher","award":["2024RCZXZK70"],"award-info":[{"award-number":["2024RCZXZK70"]}],"id":[{"id":"10.13039\/501100004863","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>Antibiotic residues in aquatic products pose a serious food safety concern, whereas conventional laboratory methods often fail to meet the demand for on-site rapid screening. This study systematically reviews the research progress from 2021 to 2025 on both the risks of antibiotic residues in aquatic products and the development of rapid on-site detection technologies. First, based on a literature survey covering major aquatic products (e.g., fish, shrimp, and shellfish), the widespread occurrence of multiple antibiotics at high concentrations was documented, with quinolones and sulfonamides identified as the most frequently detected classes. To address the need for on-site testing, this review focuses on six rapid detection techniques: fluorescent sensor (FRS), lateral flow immunoassay (LFIA), surface-enhanced Raman scattering (SERS), enzyme-linked immunosorbent assay (ELISA), electrochemical sensor (ECRS), and colorimetric sensor (CRS). The core principles, technical advantages, recent application cases (e.g., integration with smartphones and novel nanomaterials), and development trends for each method are analyzed. Finally, it discusses the current challenges faced by existing on-site detection approaches and their potential solutions. Technology selection strategies tailored to different application scenarios (e.g., aquaculture farms, distribution channels, and consumer-level use) are also proposed.<\/jats:p>","DOI":"10.3390\/foods15071264","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T12:03:47Z","timestamp":1775563427000},"page":"1264","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Systematic Review of On-Site Rapid Detection Methods for Antibiotic Residues in Aquatic Products (2021\u20132025)"],"prefix":"10.3390","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-1966-4927","authenticated-orcid":false,"given":"Guangyao","family":"Ying","sequence":"first","affiliation":[{"name":"Taizhou Institute for Food and Drug Control, Taizhou 318000, China"},{"name":"Taizhou Key Laboratory of Model Animal and Preclinical Pharmaceutical Research, Taizhou 318000, China"},{"name":"Key Laboratory for Quality Safety and Quality Improvement of Characteristic Agricultural Products in Taizhou City, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Wang","sequence":"additional","affiliation":[{"name":"Taizhou Center for Disease Control and Prevention, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunlun","family":"Li","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, Jinhua Academy, Zhejiang Chinese Medical University, Hangzhou 310053, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Wang","sequence":"additional","affiliation":[{"name":"Taizhou Institute for Food and Drug Control, Taizhou 318000, China"},{"name":"Taizhou Key Laboratory of Model Animal and Preclinical Pharmaceutical Research, Taizhou 318000, China"},{"name":"Key Laboratory for Quality Safety and Quality Improvement of Characteristic Agricultural Products in Taizhou City, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinjun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Taizhou Institute for Food and Drug Control, Taizhou 318000, China"},{"name":"Taizhou Key Laboratory of Model Animal and Preclinical Pharmaceutical Research, Taizhou 318000, China"},{"name":"Key Laboratory for Quality Safety and Quality Improvement of Characteristic Agricultural Products in Taizhou City, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gangjian","family":"Lin","sequence":"additional","affiliation":[{"name":"Taizhou Institute for Food and Drug Control, Taizhou 318000, China"},{"name":"Taizhou Key Laboratory of Model Animal and Preclinical Pharmaceutical Research, Taizhou 318000, China"},{"name":"Key Laboratory for Quality Safety and Quality Improvement of Characteristic Agricultural Products in Taizhou City, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[{"name":"Taizhou Institute for Food and Drug Control, Taizhou 318000, China"},{"name":"Taizhou Key Laboratory of Model Animal and Preclinical Pharmaceutical Research, Taizhou 318000, China"},{"name":"Key Laboratory for Quality Safety and Quality Improvement of Characteristic Agricultural Products in Taizhou City, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huili","family":"Xia","sequence":"additional","affiliation":[{"name":"Taizhou Institute for Food and Drug Control, Taizhou 318000, China"},{"name":"Taizhou Key Laboratory of Model Animal and Preclinical Pharmaceutical Research, Taizhou 318000, China"},{"name":"Key Laboratory for Quality Safety and Quality Improvement of Characteristic Agricultural Products in Taizhou City, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinjie","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Food Science and Engineering, Ningbo University, Ningbo 315211, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Hong","sequence":"additional","affiliation":[{"name":"Taizhou Institute for Food and Drug Control, Taizhou 318000, China"},{"name":"Taizhou Key Laboratory of Model Animal and Preclinical Pharmaceutical Research, Taizhou 318000, China"},{"name":"Key Laboratory for Quality Safety and Quality Improvement of Characteristic Agricultural Products in Taizhou City, Taizhou 318000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.ijantimicag.2018.11.010","article-title":"Antibiotic discovery: History, methods and perspectives","volume":"53","author":"Durand","year":"2019","journal-title":"Int. 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