{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T12:18:48Z","timestamp":1789042728819,"version":"build-2803163510"},"reference-count":60,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Jiangxi Special Research Program for Selenium-enriched Agriculture Industry Improvement","award":["FXNY2026"],"award-info":[{"award-number":["FXNY2026"]}]},{"name":"Outstanding Youth Science Foundation of Jiangxi Province","award":["20252BAC220039"],"award-info":[{"award-number":["20252BAC220039"]}]},{"name":"Ganzhou Sci-Tech Planning Project-Exploratory Project","award":["[2025] 23"],"award-info":[{"award-number":["[2025] 23"]}]},{"name":"Ganzhou Sci-Tech Planning Project-Key Research and Development Program","award":["[2024] 33"],"award-info":[{"award-number":["[2024] 33"]}]},{"DOI":"10.13039\/501100004479","name":"Jiangxi Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["20232BAB215052"],"award-info":[{"award-number":["20232BAB215052"]}],"id":[{"id":"10.13039\/501100004479","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004479","name":"Jiangxi Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["20242BAB25390"],"award-info":[{"award-number":["20242BAB25390"]}],"id":[{"id":"10.13039\/501100004479","id-type":"DOI","asserted-by":"publisher"}]},{"award":["20232BAB215052"],"award-info":[{"award-number":["20232BAB215052"]}],"id":[{"id":"https:\/\/ror.org\/04aqat463","id-type":"ROR","asserted-by":"publisher"}]},{"award":["20242BAB25390"],"award-info":[{"award-number":["20242BAB25390"]}],"id":[{"id":"https:\/\/ror.org\/04aqat463","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>The present study evaluated the effects of dietary selenium sources on growth performance, slaughter traits, meat quality, tissue selenium deposition, and transcriptomic profiles in the longissimus dorsi muscle of Tibetan pigs. Seventy-two Tibetan pigs (initial body weight: 41.96 \u00b1 6.91 kg) were randomly allocated to four treatment groups receiving 0.5 mg\/kg selenium as either sodium selenite (SeS), selenium-enriched yeast (SeY), selenium-enriched seaweed polysaccharide (SeSP), or nano-selenium (SeN) for 60 days. Results showed that neither growth performance nor slaughter traits differed significantly among the four treatments (p &gt; 0.05). Likewise, meat quality parameters of the longissimus dorsi remained comparable across groups, with the exception of drip loss, which was significantly increased in the SeN group compared with the SeS, SeY, and SeSP groups (p &lt; 0.05), among which no differences were observed (p &gt; 0.05). Importantly, selenium contents in the kidney, liver, heart, and longissimus dorsi were markedly elevated in the SeY group relative to the other three groups (p &lt; 0.05). Longissimus dorsi transcriptome analysis identified 34 overlapping differentially expressed genes (DEGs) among the three pairwise comparisons (SeS vs. SeY, SeSP vs. SeY, and SeN vs. SeY), such as S100A1, S100A6, and COL22A1 (p &lt; 0.05). Functional enrichment analysis revealed that response to external stimulus and extracellular region (GO terms), as well as viral protein interaction with cytokine and cytokine receptor (KEGG pathway), represented shared enriched annotations across all comparisons. In conclusion, selenium-enriched yeast at 0.5 mg\/kg proved superior to the alternative selenium sources in promoting selenium bioaccumulation in longissimus dorsi of Tibetan pigs. The resultant selenium-enriched muscle tissue exhibited potential beneficial functions including external stimulus response, extracellular region homeostasis, and cytokine\u2013cytokine receptor crosstalk.<\/jats:p>","DOI":"10.3390\/foods15183202","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T11:38:39Z","timestamp":1789040319000},"page":"3202","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of Dietary Selenium Sources on Meat Quality, Tissue Selenium Deposition, and Transcriptome Profiling of Longissimus dorsi Muscle in Tibetan Pigs"],"prefix":"10.3390","volume":"15","author":[{"given":"Xiaobo","family":"Guo","sequence":"first","affiliation":[{"name":"Jiangxi Province Key Laboratory of Animal Nutrition and Feed, Jiangxi Agricultural University, Nanchang 330045, China"},{"name":"Ganzhou Animal Husbandry and Fisheries Research Institute, Ganzhou 341000, 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China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"}]},{"given":"Daibo","family":"Fu","sequence":"additional","affiliation":[{"name":"Jiujiang Academy of Agriculture Sciences, Jiujiang 332000, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"data-curation","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"given":"Minfeng","family":"Ding","sequence":"additional","affiliation":[{"name":"Jiangxi Province Key Laboratory of Animal Nutrition and Feed, Jiangxi Agricultural University, Nanchang 330045, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"},{"role":"software","vocabulary":"credit"}]},{"given":"Weican","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jiangxi Province Key Laboratory of Animal Nutrition and Feed, Jiangxi Agricultural University, Nanchang 330045, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"methodology","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"investigation","vocabulary":"credit"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5651-4014","authenticated-orcid":false,"given":"Xingping","family":"Chen","sequence":"additional","affiliation":[{"name":"Jiangxi Province Key Laboratory of Animal Nutrition and Feed, Jiangxi Agricultural University, Nanchang 330045, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"software","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Jiangxi Province Key Laboratory of Animal Nutrition and Feed, Jiangxi Agricultural University, Nanchang 330045, 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Anim. Sci. Biotechnol."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.envint.2017.12.035","article-title":"Selenium distribution in the Chinese environment and its relationship with human health: A review","volume":"112","author":"Dinh","year":"2018","journal-title":"Environ. Int."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1002\/jsfa.2943","article-title":"Increased intakes of selenium-enriched foods may benefit human health","volume":"87","author":"Finley","year":"2007","journal-title":"J. Sci. Food Agric."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tifs.2018.03.021","article-title":"Advances in selenium-enriched foods: From the farm to the fork","volume":"76","author":"Wan","year":"2018","journal-title":"Trends Food Sci. Technol."},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s40104-026-01446-3","article-title":"Se-enriched yeast improves meat quality through glycerophospholipid metabolism in finishing pigs: Insights from a multi-omics analysis","volume":"17","author":"Qiu","year":"2026","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"ref_6","unstructured":"National Research Council (NRC) (2012). Nutrient Requirements of Swine, National Academies Press."},{"key":"ref_7","unstructured":"(2020). Nutrient Requirements of Swine (Standard No. GB\/T 39235-2020)."},{"key":"ref_8","unstructured":"ARC (1981). The Nutrient Requirements of Pigs, Common Wealth Agricultural Bureaux."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Ju, Y., Liu, M., Huang, L., Luo, Y., Qi, L., Ye, J., Wu, X., Cao, N., Bo, J., and Liu, X. (2021). Effects of selenium Auricularia cornea culture supplementation on growth performance, antioxidant status, tissue selenium concentration and meat quality in growing-finishing pigs. Animals, 11.","DOI":"10.3390\/ani11092701"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jtemb.2019.07.004","article-title":"Increasing selenium supplementation to a moderately-reduced energy and protein diet improves antioxidant status and meat quality without affecting growth performance in finishing pigs","volume":"56","author":"Chen","year":"2019","journal-title":"J. Trace Elem. Med. Biol."},{"key":"ref_11","doi-asserted-by":"crossref","unstructured":"Danso, O.P., Asante-Badu, B., Zhang, Z., Song, J., Wang, Z., Yin, X., and Zhu, R. (2023). Selenium biofortification: Strategies, progress and challenges. Agriculture, 13.","DOI":"10.3390\/agriculture13020416"},{"key":"ref_12","doi-asserted-by":"crossref","unstructured":"Kieliszek, M., Bierla, K., Jim\u00e9nez-Lamana, J., Kot, A.M., Alc\u00e1ntara-Dur\u00e1n, J., Piwowarek, K., B\u0142a\u017cejak, S., and Szpunar, J. (2020). Metabolic response of the yeast Candida utilis during enrichment in selenium. Int. J. Mol. Sci., 21.","DOI":"10.3390\/ijms21155287"},{"key":"ref_13","doi-asserted-by":"crossref","unstructured":"Zhou, W., Yang, Z., Han, J., Chen, X., Zou, T., You, J., and Chen, J. (2024). An updated review of emerging sources of selenium in weaned piglet nutrition. Animals, 14.","DOI":"10.3390\/ani14172599"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.anifeedsci.2016.08.022","article-title":"Selenium and vitamin E in sow diets: I. Effect on antioxidant status and reproductive performance in multiparous sows","volume":"221","author":"Chen","year":"2016","journal-title":"Anim. Feed. Sci. Technol."},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Zhong, H., Huang, Z., Li, L., Chen, X., Zou, T., Chen, J., and You, J. (2024). Selenomethionine supplementation mitigates liver dysfunction, oxidative injury and apoptosis through enhancing antioxidant capacity and inhibiting JNK MAPK pathway in piglets fed deoxynivalenol-contaminated diets. Antioxidants, 13.","DOI":"10.3390\/antiox13030295"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Huang, Z., Zhong, H., Li, T., Wang, Z., Chen, X., Zou, T., You, J., and Chen, J. (2024). Selenomethionine alleviates deoxynivalenol-induced oxidative injury in porcine intestinal epithelial cells independent of MAPK pathway regulation. Antioxidants, 13.","DOI":"10.3390\/antiox13030356"},{"key":"ref_17","doi-asserted-by":"crossref","unstructured":"Gorska, S., Maksymiuk, A., and Tur\u0142o, J. (2021). Selenium-containing polysaccharides\u2014Structural diversity, biosynthesis, chemical modifications and biological activity. Appl. Sci., 11.","DOI":"10.3390\/app11083717"},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Ponton, D.E., Graves, S.D., Fortin, C., Janz, D., Amyot, M., and Schiavon, M. (2020). Selenium interactions with algae: Chemical processes at biological uptake sites, bioaccumulation, and intracellular metabolism. Plants, 9.","DOI":"10.3390\/plants9040528"},{"key":"ref_19","doi-asserted-by":"crossref","unstructured":"Wang, S., Tang, C., Li, J., Wang, Z., Meng, F., Luo, G., Xin, H., Zhong, J., Wang, Y., and Li, B. (2022). The effects of dietary inclusion of mulberry leaf powder on growth performance, carcass traits and meat quality of Tibetan pigs. Animals, 12.","DOI":"10.3390\/ani12202743"},{"key":"ref_20","doi-asserted-by":"crossref","unstructured":"Yang, L., Tao, A., Hu, H., Ding, M., Chen, J., Li, X., Chen, X., Zou, T., and You, J. (2026). Improving meat quality and lipid metabolism of finishing pigs by replacing dietary soybean meal with enzyme\u2013bacteria co-fermented rapeseed meal. Foods, 15.","DOI":"10.3390\/foods15030587"},{"key":"ref_21","unstructured":"(2004). Technical Regulation for Testing of Carcass Traits in Lean-Type Pig (Standard No. NYT825-2004)."},{"key":"ref_22","unstructured":"(2016). Determination of Moisture in Foods (Standard No. GB 5009.3-2016)."},{"key":"ref_23","unstructured":"(2016). Determination of Protein in Foods (Standard No. GB 5009.5-2016)."},{"key":"ref_24","unstructured":"(2016). Determination of Fat in Food (Standard No. GB 5009.6-2016)."},{"key":"ref_25","unstructured":"(2016). Determination of Ash in Food (Standard No. GB 5009.4-2016)."},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Zhang, J., Zhang, C., Meng, S., Wang, H., Liu, D., Guo, L., and Miao, Z. (2025). Evaluation of the effects of acorns on the meat quality and transcriptome profile of finishing Yuxi pigs. Animals, 15.","DOI":"10.3390\/ani15050614"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"55","DOI":"10.5713\/ajas.2006.55","article-title":"Effects of dietary selenium supplementation on growth performance, selenium retention in tissues and nutrient digestibility in growing-finishing pigs","volume":"19","author":"Tian","year":"2006","journal-title":"Asian-Australas. J. Anim. Sci."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.anifeedsci.2006.03.020","article-title":"Effects of different selenium source on selenium distribution, loin quality and antioxidant status in finishing pigs","volume":"132","author":"Zhan","year":"2007","journal-title":"Anim. Feed. Sci. Technol."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/fsn3.182","article-title":"Pig feeds rich in rapeseed products and organic selenium increased omega-3 fatty acids and selenium in pork meat and backfat","volume":"3","author":"Haug","year":"2015","journal-title":"Food Sci. Nutr."},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s40104-024-01051-2","article-title":"Nano-Se exhibits limited protective effect against heat stress induced poor breast muscle meat quality of broilers compared with other selenium sources","volume":"15","author":"Jing","year":"2024","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"2172","DOI":"10.2527\/1999.7782172x","article-title":"Effects of dietary levels of selenium-enriched yeast and sodium selenite as selenium sources fed to growing-finishing pigs on performance, tissue selenium, serum glutathione peroxidase activity, carcass characteristics, and loin quality","volume":"77","author":"Mahan","year":"1999","journal-title":"J. Anim. Sci."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1007\/s12011-019-01949-3","article-title":"Effect of different selenium sources on growth performance, tissue selenium content, meat quality, and selenoprotein gene expression in finishing pigs","volume":"196","author":"Zhang","year":"2020","journal-title":"Biol. Trace Elem. Res."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.meatsci.2017.03.014","article-title":"Dietary linseed oil supplemented with organic selenium improved the fatty acid nutritional profile, muscular selenium deposition, water retention, and tenderness of fresh pork","volume":"131","author":"Jiang","year":"2017","journal-title":"Meat Sci."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"104057","DOI":"10.1016\/j.psj.2024.104057","article-title":"Comparative effects of various dietary selenium sources on growth performance, meat quality, essential trace elements content, and antioxidant capacity in broilers","volume":"103","author":"Chen","year":"2024","journal-title":"Poult. Sci."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.cbi.2008.09.008","article-title":"Characteristics of transport of selenoamino acids by epithelial amino acid transporters","volume":"177","author":"Nickel","year":"2009","journal-title":"Chem. Biol. Interact."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1017\/S0007114512004412","article-title":"An in vitro investigation of species-dependent intestinal transport of selenium and the impact of this process on selenium bioavailability","volume":"109","author":"Thiry","year":"2013","journal-title":"Br. J. Nutr."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.1007\/s00253-015-6650-x","article-title":"Accumulation and metabolism of selenium by yeast cells","volume":"99","author":"Kieliszek","year":"2015","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"ref_38","doi-asserted-by":"crossref","unstructured":"Bano, I., Jeevanandam, J., and Tsenov, G. (2025). In vitro study of selenomethionine\u2019s concentration-dependent effects in a 6-OHDA model of Parkinson\u2019s disease. In Vitro Model.","DOI":"10.1007\/s44164-025-00095-6"},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"C891","DOI":"10.1152\/ajpcell.00180.2010","article-title":"S100A1 promotes action potential-initiated calcium release flux and force production in skeletal muscle","volume":"299","author":"Prosser","year":"2010","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s40364-023-00515-3","article-title":"S100A6: Molecular function and biomarker role","volume":"11","author":"Wang","year":"2023","journal-title":"Biomark. Res."},{"key":"ref_41","doi-asserted-by":"crossref","unstructured":"Yang, R., Roshani, D., Gao, B., Li, P., and Shang, N. (2024). Metallothionein: A comprehensive review of its classification, structure, biological functions, and applications. Antioxidants, 13.","DOI":"10.3390\/antiox13070825"},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"4602","DOI":"10.1242\/dev.096024","article-title":"Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction","volume":"140","author":"Charvet","year":"2013","journal-title":"Development"},{"key":"ref_43","doi-asserted-by":"crossref","unstructured":"Imanaka-Yoshida, K., and Aoki, H. (2014). Tenascin-C and mechanotransduction in the development and diseases of cardiovascular system. Front. Physiol., 5.","DOI":"10.3389\/fphys.2014.00283"},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1186\/s13075-015-0877-x","article-title":"The interaction of lubricin\/proteoglycan 4 (PRG4) with toll-like receptors 2 and 4: An anti-inflammatory role of PRG4 in synovial fluid","volume":"17","author":"Alquraini","year":"2015","journal-title":"Arthritis Res. Ther."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.mucimm.2023.01.001","article-title":"CD200R1 promotes interleukin-17 production by group 3 innate lymphoid cells by enhancing signal transducer and activator of transcription 3 activation","volume":"16","author":"Linley","year":"2023","journal-title":"Mucosal Immunol."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"146","DOI":"10.3892\/etm.2026.13141","article-title":"FCER1G: A multifunctional regulator in the immune microenvironment","volume":"31","author":"Zhang","year":"2026","journal-title":"Exp. Ther. Med."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/icb.2014.86","article-title":"Tubulin-and actin-associating GIMAP4 is required for IFN-\u03b3 secretion during Th cell differentiation","volume":"93","author":"Heinonen","year":"2015","journal-title":"Immunol. Cell Biol."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.2147\/OTT.S237162","article-title":"IFI30 is a novel immune-related target with predicting value of prognosis and treatment response in glioblastoma","volume":"13","author":"Zhu","year":"2020","journal-title":"OncoTargets Ther."},{"key":"ref_49","doi-asserted-by":"crossref","unstructured":"Al-Khayyat, W., Laframboise, T., Dougherty, J., Mendonca, M.S., Boreham, D.R., Tai, T., Thome, C., and Tharmalingam, S. (2025). FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks. Front. Cell Dev. Biol., 13.","DOI":"10.3389\/fcell.2025.1659986"},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"5458","DOI":"10.1093\/nar\/gki855","article-title":"Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription","volume":"33","author":"Christensen","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1038\/s12276-025-01467-4","article-title":"Temporal single-cell sequencing analysis reveals that GPNMB-expressing macrophages potentiate muscle regeneration","volume":"57","author":"Chen","year":"2025","journal-title":"Exp. Mol. Med."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1023\/A:1007503919265","article-title":"Scinderin, a Ca2+-dependent actin filament severing protein that controls cortical actin network dynamics during secretion","volume":"25","author":"Trifaro","year":"2000","journal-title":"Neurochem. Res."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"RP90531","DOI":"10.7554\/eLife.90531.4","article-title":"Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation","volume":"12","author":"Hadebe","year":"2025","journal-title":"eLife"},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1161\/ATVBAHA.109.200451","article-title":"Hyaluronic acid binding protein 2 is a novel regulator of vascular integrity","volume":"30","author":"Mambetsariev","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.1111\/jcmm.16116","article-title":"PRSS55 plays an important role in the structural differentiation and energy metabolism of sperm and is required for male fertility in mice","volume":"25","author":"Zhu","year":"2021","journal-title":"J. Cell Mol. Med."},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"eadh9219","DOI":"10.1126\/sciadv.adh9219","article-title":"Serine protease 35 regulates the fibroblast matrisome in response to hyperosmotic stress","volume":"9","author":"Cernakova","year":"2023","journal-title":"Sci. Adv."},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.4103\/NRR.NRR-D-24-00094","article-title":"NECAB family of neuronal calcium-binding proteins in health and disease","volume":"20","author":"Bueno","year":"2025","journal-title":"Neural Regen. Res."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1136\/jnnp-2022-330504","article-title":"UNC13A in amyotrophic lateral sclerosis: From genetic association to therapeutic target","volume":"94","author":"Willemse","year":"2023","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"jeb251288","DOI":"10.1242\/jeb.251288","article-title":"Past environments modulate response to fluctuating temperatures in a marine fish species, Sebastes fasciatus","volume":"228","author":"Leung","year":"2025","journal-title":"J. Exp. Biol."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"327","DOI":"10.2174\/187152706777452281","article-title":"Galanin\/GALP receptors and CNS homeostatic processes","volume":"5","author":"Robinson","year":"2006","journal-title":"CNS Neurol. Disord. 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