{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T09:07:18Z","timestamp":1789636038935,"version":"4.0.0"},"reference-count":70,"publisher":"MDPI AG","issue":"18","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011787","name":"Heilongjiang Province Natural Science Foundation of China","doi-asserted-by":"publisher","award":["LH2024C126"],"award-info":[{"award-number":["LH2024C126"]}],"id":[{"id":"10.13039\/501100011787","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010616","name":"Heilongjiang Province plant food processing technology advantages characteristic discipline science and technology research project","doi-asserted-by":"publisher","award":["YSTSXK202409"],"award-info":[{"award-number":["YSTSXK202409"]}],"id":[{"id":"10.13039\/501100010616","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003851","name":"Heilongjiang Province basic scientific research operating expenses scientific research projects","doi-asserted-by":"publisher","award":["145409125"],"award-info":[{"award-number":["145409125"]}],"id":[{"id":"10.13039\/501100003851","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010616","name":"Qiqihar University","doi-asserted-by":"publisher","award":["X202510232147"],"award-info":[{"award-number":["X202510232147"]}],"id":[{"id":"10.13039\/501100010616","id-type":"DOI","asserted-by":"publisher"}]},{"award":["X202510232147"],"award-info":[{"award-number":["X202510232147"]}],"id":[{"id":"https:\/\/ror.org\/01khf5d59","id-type":"ROR","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foods"],"abstract":"<jats:p>In this study, corn protein hydrolysates (CPT) were prepared via enzymatic hydrolysis using Alcalase and Protamex, and then fractionated by ultrafiltration into three molecular weight components: &gt;5 kDa (CPT1), 3\u20135 kDa (CPT2), and &lt;3 kDa (CPT3). The physicochemical, functional and in vitro antioxidant properties of each component were systematically compared. Subsequently, glutamine peptides were isolated and identified from CPT3 using LC-MS\/MS technology, and the structural characteristics of the identified peptides were further analyzed. The results showed that the ultrafiltration fractionation effectively enriched peptides with lower molecular weights from the enzymatically hydrolyzed products, which may potentially enhance their bioavailability. In addition, CPT3 exhibited superior foaming ability, emulsifying ability, dispersibility, and zeta potential, along with lower particle size and viscosity. Moreover, CPT3 exhibited strong antioxidant activity, with IC50 values for ABTS radical scavenging and hydroxyl radical scavenging of 0.042 \u00b1 0.003 mg\/mL and 0.807 \u00b1 0.019 mg\/mL, respectively. Finally, 205 glutamine peptides were further identified from CPT3, and their structural characterization revealed that the identified peptides were rich in hydrophobic amino acids and had a high affinity for membrane proteins, which could serve as potential ligands for regulating intestinal barrier dysfunction. In summary, CPT3 possesses excellent functional properties and antioxidant activity, indicating its potential for development and application in functional and health foods.<\/jats:p>","DOI":"10.3390\/foods15183283","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T08:03:17Z","timestamp":1789632197000},"page":"3283","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Molecular Weight-Dependent Functional and Antioxidant Properties of Glutamine-Rich Corn Protein Hydrolysate: Insights into the Predicted Structural Characteristics of Identified Peptides"],"prefix":"10.3390","volume":"15","author":[{"given":"Yan","family":"Jing","sequence":"first","affiliation":[{"name":"Heilongjiang Provincial Key Laboratory of Corn Deep Processing Theory and Technology, College of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China"},{"name":"Engineering Research Center of Plant Food Processing Technology, Ministry of Education, Qiqihar 161006, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"}]},{"given":"Yating","family":"He","sequence":"additional","affiliation":[{"name":"Heilongjiang Provincial Key Laboratory of Corn Deep Processing Theory and Technology, College of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-original-draft","vocabulary":"credit"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"data-curation","vocabulary":"credit"}]},{"given":"Zedan","family":"Liu","sequence":"additional","affiliation":[{"name":"Heilongjiang Provincial Key Laboratory of Corn Deep Processing Theory and Technology, College of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"}]},{"given":"Nanxin","family":"Hong","sequence":"additional","affiliation":[{"name":"Heilongjiang Provincial Key Laboratory of Corn Deep Processing Theory and Technology, College of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"investigation","vocabulary":"credit"},{"role":"validation","vocabulary":"credit"}]},{"given":"Xiaolan","family":"Liu","sequence":"additional","affiliation":[{"name":"Heilongjiang Provincial Key Laboratory of Corn Deep Processing Theory and Technology, College of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China"},{"name":"Engineering Research Center of Plant Food Processing Technology, Ministry of Education, Qiqihar 161006, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"formal-analysis","vocabulary":"credit"},{"role":"supervision","vocabulary":"credit"}]},{"given":"Jinyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Heilongjiang Provincial Key Laboratory of Corn Deep Processing Theory and Technology, College of Food and Bioengineering, Qiqihar University, Qiqihar 161006, China"},{"name":"Engineering Research Center of Plant Food Processing Technology, Ministry of Education, Qiqihar 161006, China"}],"role":[{"vocabulary":"crossref","role":"author"},{"role":"writing-review-editing","vocabulary":"credit"},{"role":"resources","vocabulary":"credit"},{"role":"methodology","vocabulary":"credit"},{"role":"funding-acquisition","vocabulary":"credit"}]}],"member":"1968","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","unstructured":"Coqueiro, A.Y., Rogero, M.M., and Tirapegui, J. (2019). Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition. Nutrients, 11.","DOI":"10.3390\/nu11040863"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1021\/acs.jced.7b00486","article-title":"Solubility of the Proteinogenic \u03b1-Amino Acids in Water, Ethanol, and Ethanol-Water Mixtures","volume":"63","author":"Bowden","year":"2018","journal-title":"J. Chem. Eng. Data"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"7730","DOI":"10.1039\/D2FO01063A","article-title":"Novel Peptides from Sea Cucumber Intestinal Hydrolysates Promote Longitudinal Bone Growth in Adolescent Mice through Accelerating Cell Cycle Progress by Regulating Glutamine Metabolism","volume":"13","author":"Yue","year":"2022","journal-title":"Food Funct."},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"735748","DOI":"10.1016\/j.aquaculture.2020.735748","article-title":"Dietary Ala-Gln Ameliorated Growth Suppression and Intestinal Injury Induced by Soya Saponin in Zebrafish","volume":"529","author":"Tian","year":"2020","journal-title":"Aquaculture"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.rvsc.2021.04.027","article-title":"Protective Effect of Glutamine and Alanyl-Glutamine against Zearalenone-Induced Intestinal Epithelial Barrier Dysfunction in IPEC-J2 Cells","volume":"137","author":"Gu","year":"2021","journal-title":"Res. Vet. Sci."},{"key":"ref_6","doi-asserted-by":"crossref","unstructured":"Hu, J., Ying, H., Zheng, Y., Ma, H., Li, L., and Zhao, Y. (2022). Alanyl-Glutamine Protects against Lipopolysaccharide-Induced Liver Injury in Mice via Alleviating Oxidative Stress, Inhibiting Inflammation, and Regulating Autophagy. Antioxidants, 11.","DOI":"10.3390\/antiox11061070"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s00217-020-03450-x","article-title":"Identification of Immunomodulatory Peptides from Zein Hydrolysates","volume":"246","author":"Liu","year":"2020","journal-title":"Eur. Food Res. Technol."},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.tifs.2022.02.026","article-title":"Advances in the Activity Evaluation and Cellular Regulation Pathways of Food-Derived Antioxidant Peptides","volume":"122","author":"Lv","year":"2022","journal-title":"Trends Food Sci. Technol."},{"key":"ref_9","doi-asserted-by":"crossref","unstructured":"Petcu, C.D., Mihai, O.D., T\u0103p\u0103loag\u0103, D., Gheorghe-Irimia, R.-A., Pogurschi, E.N., Militaru, M., Borda, C., and Ghimpe\u021beanu, O.-M. (2023). Effects of Plant-Based Antioxidants in Animal Diets and Meat Products: A Review. Foods, 12.","DOI":"10.3390\/foods12061334"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.jff.2015.12.003","article-title":"Structure\u2013Activity Relationship of Antioxidant Dipeptides: Dominant Role of Tyr, Trp, Cys and Met Residues","volume":"21","author":"Zheng","year":"2016","journal-title":"J. Funct. Foods"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"106232","DOI":"10.1016\/j.jff.2024.106232","article-title":"Corn Protein Hydrolysate with Glutamine-Rich Peptides Protects Intestinal Barrier in Caco-2 Cells: Insights into Structural Characteristics of Identified Glutamine Peptides","volume":"117","author":"Jing","year":"2024","journal-title":"J. Funct. Foods"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.foodres.2018.08.068","article-title":"Identification and Characterization of Antioxidative Peptides Derived from Simulated In Vitro Gastrointestinal Digestion of Walnut Meal Proteins","volume":"116","author":"Feng","year":"2019","journal-title":"Food Res. Int."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"C2174","DOI":"10.1111\/1750-3841.12686","article-title":"Evaluation of antioxidant activities of zein protein fractions","volume":"79","author":"Tang","year":"2014","journal-title":"J. Food Sci."},{"key":"ref_14","doi-asserted-by":"crossref","unstructured":"Li, G., Liu, X., Miao, Z., Zhao, Y., Wang, Q., and Zheng, X. (2026). From Corn Gluten Meal to Bioactive Glutamine Peptides: Stepwise Enzymatic Release, Peptidomics Analysis, and Identification of a Novel Peptide QFSLP Alleviates LPS-Induced Inflammation. Foods, 15.","DOI":"10.3390\/foods15162904"},{"key":"ref_15","doi-asserted-by":"crossref","unstructured":"Jing, Y., Liu, X., Wang, J., Ma, Y., and Zheng, X. (2022). Production of Corn Protein Hydrolysate with Glutamine-Rich Peptides and Its Antagonistic Function in Ulcerative Colitis In Vivo. Foods, 11.","DOI":"10.3390\/foods11213359"},{"key":"ref_16","doi-asserted-by":"crossref","unstructured":"Simu, S.Y., Alam, M.B., and Kim, S.Y. (2022). The Activation of Nrf2\/HO-1 by 8-Epi-7-deoxyloganic Acid Attenuates Inflammatory Symptoms through the Suppression of the MAPK\/NF-\u03baB Signaling Cascade in In Vitro and In Vivo Models. Antioxidants, 11.","DOI":"10.3390\/antiox11091765"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"103324","DOI":"10.1016\/j.ifset.2023.103324","article-title":"pH and Ultrasound Driven Structure-Function Relationships of Soy Protein Hydrolysate","volume":"85","author":"Yang","year":"2023","journal-title":"Innov. Food Sci. Emerg. Technol."},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"e13243","DOI":"10.1111\/jfbc.13243","article-title":"Study on Physicochemical Properties and Antioxidant Activity of Polysaccharides from Desmodesmus armatus","volume":"44","author":"Cao","year":"2020","journal-title":"J. Food Biochem."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"128765","DOI":"10.1016\/j.foodchem.2020.128765","article-title":"Physicochemical Properties and Antioxidant Activities of Tree Peony (Paeonia suffruticosa Andr.) Seed Protein Hydrolysates Obtained with Different Proteases","volume":"345","author":"Wang","year":"2021","journal-title":"Food Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.foodchem.2019.01.083","article-title":"Physicochemical and Functional Properties of Chinese Quince Seed Protein Isolate","volume":"283","author":"Deng","year":"2019","journal-title":"Food Chem."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jcs.2006.04.002","article-title":"Improvement on Functional Properties of Wheat Gluten by Enzymatic Hydrolysis and Ultrafiltration","volume":"44","author":"Wang","year":"2006","journal-title":"J. Cereal Sci."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"106267","DOI":"10.1016\/j.foodhyd.2020.106267","article-title":"Effect of Molecular Weight on the Emulsion Properties of Microfluidized Gelatin Hydrolysates","volume":"111","author":"Cao","year":"2021","journal-title":"Food Hydrocoll."},{"key":"ref_23","doi-asserted-by":"crossref","unstructured":"Chen, Y., Zheng, Z., Ai, Z., Zhang, Y., Tan, C.P., and Liu, Y. (2022). Exploring the Antioxidant and Structural Properties of Black Bean Protein Hydrolysate and Its Peptide Fractions. Front. Nutr., 9.","DOI":"10.3389\/fnut.2022.884537"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"141390","DOI":"10.1016\/j.foodchem.2024.141390","article-title":"Structure, Antioxidant Activity, and Neuroprotective Effect of Black Soybean (Glycine max (L.) Merr.) Protein Hydrolysates","volume":"463","author":"Li","year":"2025","journal-title":"Food Chem."},{"key":"ref_25","doi-asserted-by":"crossref","first-page":"2420372","DOI":"10.1002\/adfm.202420372","article-title":"Topographic Scanning Electronic Microscopy Reveals the 3D Surface Structure of Materials","volume":"35","author":"Sun","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"102515","DOI":"10.1016\/j.fbio.2023.102515","article-title":"Effect of Enzymatic Hydrolysis on Solubility and Surface Properties of Pea, Rice, Hemp, and Oat Proteins: Implication on High Protein Concentrations","volume":"53","author":"Shay","year":"2023","journal-title":"Food Biosci."},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"103264","DOI":"10.1016\/j.fbio.2023.103264","article-title":"Arthrospira Cell Residue Valorization: A Study on Protein Hydrolysate Production by Limited Enzymatic Hydrolysis","volume":"56","author":"Ouyang","year":"2023","journal-title":"Food Biosci."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"109221","DOI":"10.1016\/j.foodcont.2022.109221","article-title":"Improvement of Structural Characteristics and In Vitro Digestion Properties of Zein by Controlling Postharvest Ripening Process of Corn","volume":"142","author":"Zhao","year":"2022","journal-title":"Food Control"},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"116919","DOI":"10.1016\/j.lwt.2024.116919","article-title":"Plant Proteins from Semen Astragali Complanati: Functional and Physicochemical Properties and Antioxidant Activity","volume":"212","author":"Cao","year":"2024","journal-title":"LWT"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"113473","DOI":"10.1016\/j.foodres.2023.113473","article-title":"Characterization of the Structure, Antioxidant Activity and Hypoglycemic Activity of Soy (Glycine max L.) Protein Hydrolysates","volume":"173","author":"Xu","year":"2023","journal-title":"Food Res. Int."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"3665","DOI":"10.1002\/jsfa.13251","article-title":"The Structural Characteristics and Physicochemical Properties of Mung Bean Protein Hydrolysate of Protamex Induced by Ultrasound","volume":"104","author":"Bing","year":"2024","journal-title":"J. Sci. Food Agric."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1007\/s11694-022-01796-2","article-title":"Physicochemical and Antioxidant Properties of Rice Bran Protein Hydrolysates Obtained from Different Proteases","volume":"17","author":"Onsaard","year":"2023","journal-title":"J. Food Meas. Charact."},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"141181","DOI":"10.1016\/j.ijbiomac.2025.141181","article-title":"Efficacy, Physicochemical and Processing Properties of Oat Peptides Prepared via Ultrasonication-Assisted Organic Acid Hydrolysis","volume":"305","author":"Yan","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.1111\/ijfs.14161","article-title":"Modification of Rice Protein with Glutaminase for Improved Structural and Sensory Properties","volume":"54","author":"Hu","year":"2019","journal-title":"Int. J. Food Sci. Technol."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"11624","DOI":"10.1039\/D0RA00425A","article-title":"Preparation of Sheep Bone Collagen Peptide\u2013Calcium Chelate Using Enzymolysis-Fermentation Methodology and Its Structural Characterization and Stability Analysis","volume":"10","author":"Wang","year":"2020","journal-title":"RSC Adv."},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"138288","DOI":"10.1016\/j.foodchem.2023.138288","article-title":"Novel Strategy to the Characterization and Enhance the Glycemic Control Properties of Walnut-Derived Peptides via Zinc Chelation","volume":"441","author":"Zhao","year":"2024","journal-title":"Food Chem."},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"105385","DOI":"10.1016\/j.foodhyd.2019.105385","article-title":"Depositing Alginate on the Surface of Bilayer Emulsions","volume":"100","author":"Sabet","year":"2020","journal-title":"Food Hydrocoll."},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"128784","DOI":"10.1016\/j.foodchem.2020.128784","article-title":"Effect of Cold and Hot Enzyme Deactivation on the Structural and Functional Properties of Rice Dreg Protein Hydrolysates","volume":"345","author":"Xie","year":"2021","journal-title":"Food Chem."},{"key":"ref_39","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.foodres.2014.08.027","article-title":"Physico-Chemical and Functional Properties of Native and Hydrolyzed Kidney Bean (Phaseolus vulgaris L.) Protein Isolates","volume":"76","author":"Wani","year":"2015","journal-title":"Food Res. Int."},{"key":"ref_40","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.foodhyd.2018.07.052","article-title":"Effects of Zein Hydrolysates Coupled with Sage (Salvia officinalis) Extract on the Emulsifying and Oxidative Stability of Myofibrillar Protein Prepared Oil-in-Water Emulsions","volume":"87","author":"Li","year":"2019","journal-title":"Food Hydrocoll."},{"key":"ref_41","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/j.foodhyd.2018.09.023","article-title":"Effects of Different Proteases on the Emulsifying Capacity, Rheological and Structure Characteristics of Preserved Egg White Hydrolysates","volume":"87","author":"Ai","year":"2019","journal-title":"Food Hydrocoll."},{"key":"ref_42","doi-asserted-by":"crossref","first-page":"126346","DOI":"10.1016\/j.ijbiomac.2023.126346","article-title":"Physiochemical Characteristics, Morphology, and Lubricating Properties of Size-Specific Whey Protein Particles by Acid or Ion Aggregation","volume":"252","author":"Sun","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_43","doi-asserted-by":"crossref","first-page":"126139","DOI":"10.1016\/j.ijbiomac.2023.126139","article-title":"Mechanism for Improving Coconut Milk Emulsions Viscosity by Modifying Coconut Protein Structure and Coconut Milk Properties with Monosodium Glutamate","volume":"252","author":"Wu","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"ref_44","doi-asserted-by":"crossref","first-page":"106481","DOI":"10.1016\/j.bpc.2020.106481","article-title":"Characterizing Aggregate Growth and Morphology of Alanine-Rich Polypeptides as a Function of Sequence Chemistry and Solution Temperature from Scattering, Spectroscopy, and Microscopy","volume":"267","author":"Paik","year":"2020","journal-title":"Biophys. Chem."},{"key":"ref_45","doi-asserted-by":"crossref","first-page":"5547","DOI":"10.1021\/acs.jcim.4c00676","article-title":"Prediction of Vacuum Ultraviolet\/Ultraviolet Gas-Phase Absorption Spectra Using Molecular Feature Representations and Machine Learning","volume":"64","author":"Chen","year":"2024","journal-title":"J. Chem. Inf. Model."},{"key":"ref_46","doi-asserted-by":"crossref","first-page":"106123","DOI":"10.1016\/j.foodhyd.2020.106123","article-title":"Effects of Rice Bran Rancidity on Oxidation, Structural Characteristics and Interfacial Properties of Rice Bran Globulin","volume":"110","author":"Wu","year":"2021","journal-title":"Food Hydrocoll."},{"key":"ref_47","doi-asserted-by":"crossref","first-page":"111978","DOI":"10.1016\/j.foodres.2022.111978","article-title":"Physicochemical and Functional Properties of Pleurotus geesteranus Proteins","volume":"162","author":"Jin","year":"2022","journal-title":"Food Res. Int."},{"key":"ref_48","doi-asserted-by":"crossref","first-page":"110211","DOI":"10.1016\/j.foodres.2021.110211","article-title":"Physicochemical, Functional and Structural Properties of the Major Protein Fractions Extracted from Cordyceps militaris Fruit Body","volume":"142","author":"Yu","year":"2021","journal-title":"Food Res. Int."},{"key":"ref_49","doi-asserted-by":"crossref","first-page":"133397","DOI":"10.1016\/j.foodchem.2022.133397","article-title":"Physicochemical, Functional and Antioxidant Properties of Mung Bean Protein Enzymatic Hydrolysates","volume":"393","author":"Liu","year":"2022","journal-title":"Food Chem."},{"key":"ref_50","doi-asserted-by":"crossref","first-page":"S543","DOI":"10.1080\/10942912.2017.1300813","article-title":"Molecular Structural Properties of Extracted Gelatin from Yak Skin as Analysed Based on Molecular Weight","volume":"20","author":"Xu","year":"2017","journal-title":"Int. J. Food Prop."},{"key":"ref_51","doi-asserted-by":"crossref","first-page":"130837","DOI":"10.1016\/j.foodchem.2021.130837","article-title":"Properties of Protein Isolates Extracted by Ultrasonication from Soybean Residue (Okara)","volume":"368","author":"Eze","year":"2022","journal-title":"Food Chem."},{"key":"ref_52","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.foodhyd.2005.06.002","article-title":"Properties and Stability of Oil-in-Water Emulsions Stabilized by Fish Gelatin","volume":"20","author":"Surh","year":"2006","journal-title":"Food Hydrocoll."},{"key":"ref_53","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jfoodeng.2015.09.011","article-title":"Emulsifying Properties and Structure Changes of Spray and Freeze-Dried Peanut Protein Isolate","volume":"170","author":"Gong","year":"2016","journal-title":"J. Food Eng."},{"key":"ref_54","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1016\/j.jff.2013.08.013","article-title":"Purification and Identification of Antioxidant Peptides from Corn Gluten Meal","volume":"5","author":"Zhuang","year":"2013","journal-title":"J. Funct. Foods"},{"key":"ref_55","doi-asserted-by":"crossref","first-page":"109126","DOI":"10.1016\/j.lwt.2020.109126","article-title":"Optimization of Pea Protein Hydrolysate Preparation and Purification of Antioxidant Peptides Based on an In Silico Analytical Approach","volume":"123","author":"Ding","year":"2020","journal-title":"LWT"},{"key":"ref_56","doi-asserted-by":"crossref","first-page":"e27891","DOI":"10.1016\/j.heliyon.2024.e27891","article-title":"Comparison of Characteristics and Antioxidant Activities of Sesame Protein Hydrolysates and Their Fractions","volume":"10","author":"Noptana","year":"2024","journal-title":"Heliyon"},{"key":"ref_57","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.foodchem.2017.07.080","article-title":"Fractionation and Antioxidant Properties of Rice Bran Protein Hydrolysates Stimulated by In Vitro Gastrointestinal Digestion","volume":"240","author":"Phongthai","year":"2018","journal-title":"Food Chem."},{"key":"ref_58","doi-asserted-by":"crossref","first-page":"e13396","DOI":"10.1111\/jfbc.13396","article-title":"Antioxidant and Enzymes Inhibitory Properties of Amaranth Leaf Protein Hydrolyzates and Ultrafiltration Peptide Fractions","volume":"45","author":"Famuwagun","year":"2021","journal-title":"J. Food Biochem."},{"key":"ref_59","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/s11746-010-1686-7","article-title":"In Vitro Antioxidant Properties of Hemp Seed (Cannabis sativa L.) Protein Hydrolysate Fractions","volume":"88","author":"Girgih","year":"2011","journal-title":"J. Am. Oil Chem. Soc."},{"key":"ref_60","doi-asserted-by":"crossref","first-page":"5419","DOI":"10.1021\/acs.jafc.2c09094","article-title":"Potential of Food Protein-Derived Bioactive Peptides against Sarcopenia: A Comprehensive Review","volume":"71","author":"Zhu","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"ref_61","doi-asserted-by":"crossref","first-page":"25690","DOI":"10.1021\/acs.jafc.4c07217","article-title":"The Hydrophobic Amino Acid-Rich Fish Collagen Peptide Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice via Repairing the Intestinal Barrier, Regulating Intestinal Flora and AA Metabolism","volume":"72","author":"Yang","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"ref_62","doi-asserted-by":"crossref","unstructured":"Wang, J., He, Y., Liu, Z., Liu, X., and Jing, Y. (2025). Glutamine Peptides: Preparation, Analysis, Applications, and Their Role in Intestinal Barrier Protection. Nutrients, 17.","DOI":"10.3390\/nu17061017"},{"key":"ref_63","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1007\/s00726-023-03317-x","article-title":"PepAnalyzer: Predicting peptide properties using its sequence","volume":"55","author":"Rustagi","year":"2023","journal-title":"Amino Acids"},{"key":"ref_64","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/j.fshw.2019.08.002","article-title":"Antioxidant Peptides Encrypted in Flaxseed Proteome: An In Silico Assessment","volume":"8","author":"Ji","year":"2019","journal-title":"Food Sci. Hum. Wellness"},{"key":"ref_65","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s40659-016-0092-5","article-title":"50 years of amino acid hydrophobicity scales: Revisiting the capacity for peptide classification","volume":"49","author":"Simm","year":"2016","journal-title":"Biol. Res."},{"key":"ref_66","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1046\/j.1365-2796.2003.01228.x","article-title":"Antibacterial peptides: Basic facts and emerging concepts","volume":"254","author":"Boman","year":"2003","journal-title":"J. Intern. Med."},{"key":"ref_67","doi-asserted-by":"crossref","first-page":"3676","DOI":"10.1002\/jsfa.13252","article-title":"Purification, Identification and Molecular Docking of Dual-Functional Peptides Derived from Corn Protein Hydrolysates with Antioxidant and Antiadhesive Activity against Helicobacter pylori","volume":"104","author":"Li","year":"2024","journal-title":"J. Sci. Food Agric."},{"key":"ref_68","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/protein\/4.2.155","article-title":"Correlation between stability of a protein and its dipeptide composition: A novel approach for predicting in vivo stability of a protein from its primary sequence","volume":"4","author":"Guruprasad","year":"1990","journal-title":"Protein Eng."},{"key":"ref_69","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1007\/s10989-021-10239-3","article-title":"An In Silico Based Approach Towards the Characterization with Feature Identification and Analogy Modeling of Human Osteoclast Protein","volume":"27","author":"Ghosh","year":"2021","journal-title":"Int. J. Pept. Res. Ther."},{"key":"ref_70","doi-asserted-by":"crossref","first-page":"11954","DOI":"10.1021\/acs.jafc.0c04367","article-title":"Wheat Germ-Derived Peptides Exert Antiadhesive Activity against Helicobacter pylori: Insights into Structural Characteristics of Identified Peptides","volume":"68","author":"Sun","year":"2020","journal-title":"J. Agric. Food Chem."}],"container-title":["Foods"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2304-8158\/15\/18\/3283\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T09:01:42Z","timestamp":1789635702000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2304-8158\/15\/18\/3283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,17]]},"references-count":70,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2026,9]]}},"alternative-id":["foods15183283"],"URL":"https:\/\/doi.org\/10.3390\/foods15183283","relation":{},"ISSN":["2304-8158"],"issn-type":[{"value":"2304-8158","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,17]]}}}