{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T04:01:28Z","timestamp":1793160088011,"version":"4.5.0"},"reference-count":38,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T00:00:00Z","timestamp":1703980800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gels"],"abstract":"<jats:p>During the preparation of cotton cellulose hydrogels using the phase inversion gelation method of N,N-dimethylacetamide\/LiCl solution under ethanol vapor, acetone (AC), methyl ethyl ketone (MEK), or diethyl ketone (DEK) were added as additives, and their gelation state and the properties of the resulting hydrogels were evaluated. Adding the ketones to the cellulose solution caused an increase in the gelation time, but the solution viscosity decreased, indicating that the cellulose tended to aggregate in the solution. Among the hydrogels prepared by adding ketones, the water content was as high as 2050%, especially for AC and MEK. In these hydrogels, cellulose formed an agglomerated fibrous network of a few micron widths, forming a tuft-like entrapment space of about 10 to 100 \u03bcm size. The structure surrounded water and held it in the hydrogels. The FTIR results showed that the water, which formed hydrogen bonds, was retained within the hydrogel network. This structural configuration was determined to be conducive to maintaining the gel state against external deformation forces, especially in the case of the addition of MEK.<\/jats:p>","DOI":"10.3390\/gels10010034","type":"journal-article","created":{"date-parts":[[2023,12,31]],"date-time":"2023-12-31T06:00:21Z","timestamp":1704002421000},"page":"34","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Phase Inversion Gelation Process and Additive Effects on Hydrogel Film Properties of Cotton Cellulose"],"prefix":"10.3390","volume":"10","author":[{"given":"Ayano","family":"Ibaraki","sequence":"first","affiliation":[{"name":"Department of Science of Technology Innovation, Nagaoka University of Technology, Niigata 940-2188, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaomi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Science of Technology Innovation, Nagaoka University of Technology, Niigata 940-2188, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2023,12,31]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1080\/14686996.2020.1848213","article-title":"Recent Progress in the Conversion of Biomass Wastes into Functional Materials for Value-Added Applications","volume":"21","author":"Zhou","year":"2020","journal-title":"Sci. Technol. Adv. Mater."},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.renene.2022.06.026","article-title":"The Role of Sustainable Bioenergy in a Fully Decarbonised Society","volume":"196","author":"Lund","year":"2022","journal-title":"Renew. Energy"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"6457","DOI":"10.1007\/s13399-021-01853-8","article-title":"Recent Trends and Future Perspectives of Lignocellulose Biomass for Biofuel Production: A Comprehensive Review","volume":"13","author":"Jatoi","year":"2023","journal-title":"Biomass Convers. Biorefinery"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/s41578-021-00407-8","article-title":"Bioplastics for a Circular Economy","volume":"7","author":"Rosenboom","year":"2022","journal-title":"Nat. Rev. Mater."},{"key":"ref_5","doi-asserted-by":"crossref","unstructured":"Felgueiras, C., Azoia, N.G., Gon\u00e7alves, C., Gama, M., and Dourado, F. (2021). Trends on the Cellulose-Based Textiles: Raw Materials and Technologies. Front. Bioeng. Biotechnol., 9.","DOI":"10.3389\/fbioe.2021.608826"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1177\/0040517517723021","article-title":"Textile Qualities of Regenerated Cellulose Fibers from Cotton Waste Pulp","volume":"88","author":"Aronsson","year":"2018","journal-title":"Text. Res. J."},{"key":"ref_7","doi-asserted-by":"crossref","unstructured":"Heinze, T., El Seoud, O.A., and Koschella, A. (2018). Cellulose Derivatives: Synthesis, Structure, and Properties, Springer International Publishing.","DOI":"10.1007\/978-3-319-73168-1"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.biortech.2016.12.049","article-title":"Assessment of Solvents for Cellulose Dissolution","volume":"228","author":"Ghasemi","year":"2017","journal-title":"Bioresour. Technol."},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.carbpol.2016.06.015","article-title":"Dissolution State of Cellulose in Aqueous Systems. 2. Acidic Solvents","volume":"151","author":"Alves","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"6496","DOI":"10.1016\/j.biortech.2009.06.095","article-title":"The Mechanism for Thermal Decomposition of Cellulose and Its Main Products","volume":"100","author":"Shen","year":"2009","journal-title":"Bioresour. Technol."},{"key":"ref_11","unstructured":"Shen, D., Xiao, R., Gu, S., Zhang, H., Shen, D., Xiao, R., Gu, S., and Zhang, H. (2013). Cellulose\u2014Biomass Conversion, IntechOpen."},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.molliq.2010.04.016","article-title":"On the Mechanism of Dissolution of Cellulose","volume":"156","author":"Lindman","year":"2010","journal-title":"J. Mol. Liq."},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"9507","DOI":"10.1021\/jp506013c","article-title":"Dissolution Mechanism of Cellulose in N,N-Dimethylacetamide\/Lithium Chloride: Revisiting through Molecular Interactions","volume":"118","author":"Zhang","year":"2014","journal-title":"J. Phys. Chem. B"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1134\/S0965545X17010084","article-title":"Preparation of Cellulose Hydrogels via Self-Assembly in DMAc\/LiCl Solutions and Study of Their Properties","volume":"59","author":"Mikhailidi","year":"2017","journal-title":"Polym. Sci. Ser. A"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"11607","DOI":"10.1021\/ie401793w","article-title":"Fibroblast Compatibility on Scaffold Hydrogels Prepared from Agave Tequilana Weber Bagasse for Tissue Regeneration","volume":"52","author":"Sueyoshi","year":"2013","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-444-63473-3.00001-0","article-title":"Chapter 1\u2014Fabrication of Cellulose Hydrogels and Characterization of Their Biocompatible Films","volume":"Volume 45","year":"2015","journal-title":"Studies in Natural Products Chemistry"},{"key":"ref_17","unstructured":"Hashmi, M.S.J. (2022). Encyclopedia of Materials: Plastics and Polymers, Elsevier."},{"key":"ref_18","doi-asserted-by":"crossref","unstructured":"Iresha, H., and Kobayashi, T. (2021). In Situ Viscoelasticity Behavior of Cellulose-Chitin Composite Hydrogels during Ultrasound Irradiation. Gels, 7.","DOI":"10.3390\/gels7030081"},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"125717","DOI":"10.1016\/j.foodchem.2019.125717","article-title":"Celery Cellulose Hydrogel as Carriers for Controlled Release of Short-Chain Fatty Acid by Ultrasound","volume":"309","author":"Yan","year":"2020","journal-title":"Food Chem."},{"key":"ref_20","doi-asserted-by":"crossref","first-page":"100413","DOI":"10.1016\/j.cogsc.2020.100413","article-title":"Advanced Cellulose Cosmetic Facial Masks Prepared from Myanmar Thanaka Heartwood","volume":"27","author":"Cho","year":"2021","journal-title":"Curr. Opin. Green Sustain. Chem."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1021\/acs.iecr.5b03926","article-title":"Biocompatibility Evaluation of Cellulose Hydrogel Film Regenerated from Sugar Cane Bagasse Waste and Its In Vivo Behavior in Mice","volume":"55","author":"Nakasone","year":"2016","journal-title":"Ind. Eng. Chem. Res."},{"key":"ref_22","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.carbpol.2016.05.084","article-title":"Physically and Chemically Cross-Linked Cellulose Cryogels: Structure, Properties and Application for Controlled Release","volume":"151","author":"Ciolacu","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1021\/acs.biomac.6b01243","article-title":"Nanocellulose-Based Interpenetrating Polymer Network (IPN) Hydrogels for Cartilage Applications","volume":"17","author":"Naseri","year":"2016","journal-title":"Biomacromolecules"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1007\/s10853-013-7918-0","article-title":"Swelling Behaviors of Superabsorbent Chitin\/Carboxymethylcellulose Hydrogels","volume":"49","author":"Tang","year":"2014","journal-title":"J. Mater. Sci."},{"key":"ref_25","doi-asserted-by":"crossref","unstructured":"Dutta, S.D., Patel, D.K., and Lim, K.-T. (2019). Functional Cellulose-Based Hydrogels as Extracellular Matrices for Tissue Engineering. J. Biol. Eng., 13.","DOI":"10.1186\/s13036-019-0177-0"},{"key":"ref_26","doi-asserted-by":"crossref","unstructured":"Ciolacu, D.E., Nicu, R., and Ciolacu, F. (2020). Cellulose-Based Hydrogels as Sustained Drug-Delivery Systems. Materials, 13.","DOI":"10.3390\/ma13225270"},{"key":"ref_27","doi-asserted-by":"crossref","first-page":"105143","DOI":"10.1016\/j.ultsonch.2020.105143","article-title":"Ultrasound Response of Viscoelastic Changes of Cellulose Hydrogels Triggered with Sono-Deviced Rheometer","volume":"67","author":"Noguchi","year":"2020","journal-title":"Ultrason. Sonochem."},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"12794","DOI":"10.1039\/c3ra40807h","article-title":"Cellulose Regeneration from a Cellulose\/Ionic Liquid Mixture: The Role of Anti-Solvents","volume":"3","author":"Gupta","year":"2013","journal-title":"RSC Adv."},{"key":"ref_29","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1002\/cssc.201901316","article-title":"The Effect of Additives on the Viscosity and Dissolution of Cellulose in Tetrabutylphosphonium Hydroxide","volume":"12","author":"Nguyen","year":"2019","journal-title":"ChemSusChem"},{"key":"ref_30","doi-asserted-by":"crossref","first-page":"255","DOI":"10.3176\/proc.2016.3.09","article-title":"Ionic Liquids as Solvents for Making Composite Materials from Cellulose","volume":"65","author":"Elhi","year":"2016","journal-title":"Proc. Est. Acad. Sci."},{"key":"ref_31","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.eurpolymj.2009.04.033","article-title":"Superabsorbent Hydrogels Based on Cellulose for Smart Swelling and Controllable Delivery","volume":"46","author":"Chang","year":"2010","journal-title":"Eur. Polym. J."},{"key":"ref_32","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1021\/acs.jpcb.2c01702","article-title":"Infrared Spectra and Hydrogen-Bond Configurations of Water Molecules at the Interface of Water-Insoluble Polymers under Humidified Conditions","volume":"126","author":"Ikemoto","year":"2022","journal-title":"J. Phys. Chem. B"},{"key":"ref_33","doi-asserted-by":"crossref","first-page":"5560","DOI":"10.1021\/acs.jpclett.3c01054","article-title":"Probing Confinement Effects on the Infrared Spectra of Water with Deep Potential Molecular Dynamics Simulations","volume":"14","author":"Pham","year":"2023","journal-title":"J. Phys. Chem. Lett."},{"key":"ref_34","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.ultsonch.2013.01.002","article-title":"Ultrasound Effect Used as External Stimulus for Viscosity Change of Aqueous Carrageenans","volume":"20","author":"Motohiro","year":"2013","journal-title":"Ultrason. Sonochem."},{"key":"ref_35","doi-asserted-by":"crossref","first-page":"8461","DOI":"10.1016\/S0032-3861(01)00358-5","article-title":"States of Water in Different Hydrophilic Polymers\u2014DSC and FTIR Studies","volume":"42","author":"Ping","year":"2001","journal-title":"Polymer"},{"key":"ref_36","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1021\/acsomega.7b01765","article-title":"Effect of Elevated Temperatures on the States of Water and Their Correlation with the Proton Conductivity of Nafion","volume":"3","author":"Barique","year":"2018","journal-title":"ACS Omega"},{"key":"ref_37","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/bip.10245","article-title":"Hydration of Polysaccharide Hyaluronan Observed by IR Spectrometry. I. Preliminary Experiments and Band Assignments","volume":"72","author":"Haxaire","year":"2003","journal-title":"Biopolymers"},{"key":"ref_38","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1351\/pac199466081739","article-title":"Recommendations for the Characterization of Porous Solids (Technical Report)","volume":"66","author":"Rouquerol","year":"1994","journal-title":"Pure Appl. Chem."}],"container-title":["Gels"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.mdpi.com\/2310-2861\/10\/1\/34\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:45:16Z","timestamp":1760132716000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.mdpi.com\/2310-2861\/10\/1\/34"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,31]]},"references-count":38,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,1]]}},"alternative-id":["gels10010034"],"URL":"https:\/\/doi.org\/10.3390\/gels10010034","relation":{},"ISSN":["2310-2861"],"issn-type":[{"value":"2310-2861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,31]]}}}