{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T22:38:06Z","timestamp":1792449486505,"version":"4.5.0"},"reference-count":56,"publisher":"MDPI AG","issue":"1","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Hebei Science and Technology  Department Project","award":["253A7631D"],"award-info":[{"award-number":["253A7631D"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51503177"],"award-info":[{"award-number":["51503177"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Sichuan Province Engineering Technology Research  Center of Novel CN Polymeric Materials","award":["No. CNP-C-240204"],"award-info":[{"award-number":["No. CNP-C-240204"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gels"],"abstract":"<jats:p>In this work, kaolin\/chitin (K\/Ch) composite aerogels with different mass ratios were successfully fabricated via a freeze\u2013drying approach. The influence of kaolin content on the microstructure, properties and hemostatic performance of the composite aerogels was systematically investigated. The results demonstrated that the incorporation of kaolin endowed the chitin-based aerogels with tunable porous structures, excellent water absorption capacity (up to 4282% for K0.25\/Ch2), and enhanced water retention (73.7% for K2\/Ch2 at 60 min). Moreover, the K\/Ch composite aerogels exhibited good biodegradability, no cytotoxicity (cell viability &gt; 91.9%), and no hemolysis (hemolysis rate &lt; 1.5% at all test concentrations). In vitro hemostatic evaluations revealed that the composite aerogels exhibited rapid blood coagulation (blood clotting time of 16 s for K2\/Ch2) with a blood coagulation index (BCI) as low as 0.5%, which was attributed to the synergistic effect of the physical adsorption of chitin and the coagulation cascade activation by kaolin. These findings indicated that the K\/Ch composite aerogels could be used as novel natural hemostatic materials for potential effective and rapid hemostasis.<\/jats:p>","DOI":"10.3390\/gels12010076","type":"journal-article","created":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T16:21:13Z","timestamp":1768494073000},"page":"76","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Construction of Flexible Kaolin\/Chitin Composite Aerogels and Their Properties"],"prefix":"10.3390","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6209-563X","authenticated-orcid":false,"given":"Meng","family":"He","sequence":"first","affiliation":[{"name":"School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China"},{"name":"Hebei Haien Rubber & Plastic Products Co., Ltd., Cangzhou 061800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujia","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhicheng","family":"Cui","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziyue","family":"Cheng","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Cao","sequence":"additional","affiliation":[{"name":"Hebei Haien Rubber & Plastic Products Co., Ltd., Cangzhou 061800, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengna","family":"Feng","sequence":"additional","affiliation":[{"name":"School of Materials Science and Engineering, Yancheng Institute of Technology, Yancheng 224051, China"},{"name":"Sichuan Province Engineering Technology Research Center of Novel CN Polymeric Materials, Chengdu 611731, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2026,1,15]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"tkab019","DOI":"10.1093\/burnst\/tkab019","article-title":"Hemostatic materials in wound care","volume":"9","author":"Yu","year":"2021","journal-title":"Burn. 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