{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T17:03:14Z","timestamp":1787936594483,"version":"build-2784847793"},"reference-count":211,"publisher":"MDPI AG","issue":"11","license":[{"start":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T00:00:00Z","timestamp":1573171200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI16\/0142"],"award-info":[{"award-number":["PI16\/0142"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"European Union (ERDF\/ESF, \u201cInvesting in your future&quot;)","award":["PI16\/0142"],"award-info":[{"award-number":["PI16\/0142"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genes"],"abstract":"<jats:p>Thyroid cancer, a cancerous tumor or growth located within the thyroid gland, is the most common endocrine cancer. It is one of the few cancers whereby incidence rates have increased in recent years. It occurs in all age groups, from children through to seniors. Most studies are focused on dissecting its genetic basis, since our current knowledge of the genetic background of the different forms of thyroid cancer is far from complete, which poses a challenge for diagnosis and prognosis of the disease. In this review, we describe prevailing advances and update our understanding of the molecular genetics of thyroid cancer, focusing on the main genes related with the pathology, including the different noncoding RNAs associated with the disease.<\/jats:p>","DOI":"10.3390\/genes10110913","type":"journal-article","created":{"date-parts":[[2019,11,8]],"date-time":"2019-11-08T11:30:19Z","timestamp":1573212619000},"page":"913","update-policy":"https:\/\/doi.org\/10.3390\/mdpi_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Influencers on Thyroid Cancer Onset: Molecular Genetic Basis"],"prefix":"10.3390","volume":"10","author":[{"given":"Berta","family":"Luz\u00f3n-Toro","sequence":"first","affiliation":[{"name":"Department of Maternofetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, 41013 Seville, Spain"},{"name":"Centre for Biomedical Network Research on Rare Diseases (CIBERER), 41013 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Department of Maternofetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, 41013 Seville, Spain"},{"name":"Centre for Biomedical Network Research on Rare Diseases (CIBERER), 41013 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia","family":"Villalba-Benito","sequence":"additional","affiliation":[{"name":"Department of Maternofetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, 41013 Seville, Spain"},{"name":"Centre for Biomedical Network Research on Rare Diseases (CIBERER), 41013 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Torroglosa","sequence":"additional","affiliation":[{"name":"Department of Maternofetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, 41013 Seville, Spain"},{"name":"Centre for Biomedical Network Research on Rare Diseases (CIBERER), 41013 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Anti\u00f1olo","sequence":"additional","affiliation":[{"name":"Department of Maternofetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, 41013 Seville, Spain"},{"name":"Centre for Biomedical Network Research on Rare Diseases (CIBERER), 41013 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salud","family":"Borrego","sequence":"additional","affiliation":[{"name":"Department of Maternofetal Medicine, Genetics and Reproduction, Institute of Biomedicine of Seville (IBIS), University Hospital Virgen del Roc\u00edo\/CSIC\/University of Seville, 41013 Seville, Spain"},{"name":"Centre for Biomedical Network Research on Rare Diseases (CIBERER), 41013 Seville, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1968","published-online":{"date-parts":[[2019,11,8]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"162","DOI":"10.4103\/AIHB.AIHB_2_19","article-title":"Epidemiology, Incidence and Mortality of Thyroid Cancer and their Relationship with the Human Development Index in the World: An Ecology Study in 2018","volume":"9","author":"Goodarzi","year":"2019","journal-title":"Adv. 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